(25 nodes) Early endosome to late endosome transport network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rilp	Rab-interacting lysosomal protein. (368 aa)
	Pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (822 aa)
	I79_016240	Beclin-1. (119 aa)
	Wdr91	WD repeat-containing protein 91. (693 aa)
	Snx16	Sorting nexin-16. (341 aa)
	Flna	Filamin-A. (2488 aa)
	Lmtk2	Serine/threonine-protein kinase LMTK2. (1436 aa)
	Fam160a2	FTS and Hook-interacting protein-like isoform 2. (990 aa)
	I79_023066	Protein FAM184A. (852 aa)
	Kif16b	Kinesin-like protein KIF16B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1312 aa)
	Wdr81	WD repeat-containing protein 81. (1934 aa)
	Atg14	Uncharacterized protein KIAA0831. (375 aa)
	Aktip	AKT-interacting protein. (213 aa)
	I79_003250	Phosphoinositide 3-kinase regulatory subunit 4. (194 aa)
	Pik3r4	Phosphoinositide 3-kinase regulatory subunit 4. (993 aa)
	I79_002690	Syntaxin-8. (210 aa)
	Emp2	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (174 aa)
	Rab5a	Ras-related protein Rab-5A. (215 aa)
	Hook2	Protein Hook-like 2. (760 aa)
	I79_009172	Ankyrin repeat domain-containing protein 27. (845 aa)
	Rab7a	Ras-related protein Rab-7a. (207 aa)
	Snf8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	Ptpn23	Tyrosine-protein phosphatase non-receptor type 23. (1639 aa)
	Becn1	Beclin-1. (448 aa)
	I79_012696	Protein Hook-like 1. (571 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aktip	Fam160a2	G3H0R1	G3IEE1	AKT-interacting protein.	FTS and Hook-interacting protein-like isoform 2.	0.846
Aktip	Hook2	G3H0R1	G3HCW5	AKT-interacting protein.	Protein Hook-like 2.	0.750
Aktip	I79_012696	G3H0R1	G3HPI3	AKT-interacting protein.	Protein Hook-like 1.	0.822
Atg14	Becn1	G3H7A9	G3HLZ1	Uncharacterized protein KIAA0831.	Beclin-1.	0.999
Atg14	I79_003250	G3H7A9	G3GZI8	Uncharacterized protein KIAA0831.	Phosphoinositide 3-kinase regulatory subunit 4.	0.968
Atg14	I79_016240	G3H7A9	G3HYU8	Uncharacterized protein KIAA0831.	Beclin-1.	0.988
Atg14	Pik3c3	G3H7A9	G3HX36	Uncharacterized protein KIAA0831.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.999
Atg14	Pik3r4	G3H7A9	G3GZI7	Uncharacterized protein KIAA0831.	Phosphoinositide 3-kinase regulatory subunit 4.	0.997
Atg14	Wdr81	G3H7A9	G3IKX0	Uncharacterized protein KIAA0831.	WD repeat-containing protein 81.	0.595
Becn1	Atg14	G3HLZ1	G3H7A9	Beclin-1.	Uncharacterized protein KIAA0831.	0.999
Becn1	I79_003250	G3HLZ1	G3GZI8	Beclin-1.	Phosphoinositide 3-kinase regulatory subunit 4.	0.819
Becn1	Pik3c3	G3HLZ1	G3HX36	Beclin-1.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.998
Becn1	Pik3r4	G3HLZ1	G3GZI7	Beclin-1.	Phosphoinositide 3-kinase regulatory subunit 4.	0.985
Becn1	Rab5a	G3HLZ1	G3H8L7	Beclin-1.	Ras-related protein Rab-5A.	0.477
Becn1	Wdr81	G3HLZ1	G3IKX0	Beclin-1.	WD repeat-containing protein 81.	0.631
Fam160a2	Aktip	G3IEE1	G3H0R1	FTS and Hook-interacting protein-like isoform 2.	AKT-interacting protein.	0.846
Fam160a2	Hook2	G3IEE1	G3HCW5	FTS and Hook-interacting protein-like isoform 2.	Protein Hook-like 2.	0.563
Fam160a2	I79_012696	G3IEE1	G3HPI3	FTS and Hook-interacting protein-like isoform 2.	Protein Hook-like 1.	0.570
Hook2	Aktip	G3HCW5	G3H0R1	Protein Hook-like 2.	AKT-interacting protein.	0.750
Hook2	Fam160a2	G3HCW5	G3IEE1	Protein Hook-like 2.	FTS and Hook-interacting protein-like isoform 2.	0.563