(13 nodes) Positive thymic T cell selection network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Stk11	Serine/threonine-protein kinase 11. (505 aa)
	I79_011202	T-cell surface glycoprotein CD1d1. (111 aa)
	I79_012384	Leukocyte common antigen. (962 aa)
	I79_013182	Class II histocompatibility antigen, M alpha chain; Belongs to the MHC class II family. (261 aa)
	Cd74	H-2 class II histocompatibility antigen gamma chain. (329 aa)
	I79_014206	Dedicator of cytokinesis protein 2. (785 aa)
	Itpkb	Kinase; Belongs to the inositol phosphokinase (IPK) family. (789 aa)
	Srf	Serum response factor. (361 aa)
	I79_021702	Dedicator of cytokinesis protein 2. (377 aa)
	Cd3d	T-cell surface glycoprotein CD3 delta chain. (150 aa)
	I79_001953	Dedicator of cytokinesis protein 2; Belongs to the DOCK family. (763 aa)
	I79_004087	Tyrosine-protein kinase. (593 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd3d	Cd74	G3IMA2	G3HS40	T-cell surface glycoprotein CD3 delta chain.	H-2 class II histocompatibility antigen gamma chain.	0.456
Cd3d	I79_004087	G3IMA2	G3H1Q5	T-cell surface glycoprotein CD3 delta chain.	Tyrosine-protein kinase.	0.923
Cd3d	I79_011202	G3IMA2	G3HKH6	T-cell surface glycoprotein CD3 delta chain.	T-cell surface glycoprotein CD1d1.	0.551
Cd3d	I79_012384	G3IMA2	G3HNP2	T-cell surface glycoprotein CD3 delta chain.	Leukocyte common antigen.	0.721
Cd74	Cd3d	G3HS40	G3IMA2	H-2 class II histocompatibility antigen gamma chain.	T-cell surface glycoprotein CD3 delta chain.	0.456
Cd74	I79_013182	G3HS40	G3HQS6	H-2 class II histocompatibility antigen gamma chain.	Class II histocompatibility antigen, M alpha chain; Belongs to the MHC class II family.	0.987
I79_001953	I79_014206	G3GW40	G3HTI1	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Dedicator of cytokinesis protein 2.	0.900
I79_001953	I79_021702	G3GW40	G3IDC5	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	Dedicator of cytokinesis protein 2.	0.871
I79_004087	Cd3d	G3H1Q5	G3IMA2	Tyrosine-protein kinase.	T-cell surface glycoprotein CD3 delta chain.	0.923
I79_004087	I79_012384	G3H1Q5	G3HNP2	Tyrosine-protein kinase.	Leukocyte common antigen.	0.532
I79_004087	Itpkb	G3H1Q5	G3HV75	Tyrosine-protein kinase.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.495
I79_011202	Cd3d	G3HKH6	G3IMA2	T-cell surface glycoprotein CD1d1.	T-cell surface glycoprotein CD3 delta chain.	0.551
I79_011202	I79_012384	G3HKH6	G3HNP2	T-cell surface glycoprotein CD1d1.	Leukocyte common antigen.	0.418
I79_012384	Cd3d	G3HNP2	G3IMA2	Leukocyte common antigen.	T-cell surface glycoprotein CD3 delta chain.	0.721
I79_012384	I79_004087	G3HNP2	G3H1Q5	Leukocyte common antigen.	Tyrosine-protein kinase.	0.532
I79_012384	I79_011202	G3HNP2	G3HKH6	Leukocyte common antigen.	T-cell surface glycoprotein CD1d1.	0.418
I79_013182	Cd74	G3HQS6	G3HS40	Class II histocompatibility antigen, M alpha chain; Belongs to the MHC class II family.	H-2 class II histocompatibility antigen gamma chain.	0.987
I79_014206	I79_001953	G3HTI1	G3GW40	Dedicator of cytokinesis protein 2.	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.900
I79_014206	I79_021702	G3HTI1	G3IDC5	Dedicator of cytokinesis protein 2.	Dedicator of cytokinesis protein 2.	0.918
I79_021702	I79_001953	G3IDC5	G3GW40	Dedicator of cytokinesis protein 2.	Dedicator of cytokinesis protein 2; Belongs to the DOCK family.	0.871