STRINGSTRING
TARBP2 TARBP2 Hacd3 Hacd3 Ppie Ppie I79_011990 I79_011990 Larp1 Larp1 Stau1 Stau1 I79_002227 I79_002227 Pde12 Pde12 Srpk2 Srpk2 I79_008716 I79_008716 I79_008349 I79_008349 Adar Adar Fkbp6 Fkbp6 Tmem39b Tmem39b Adarb1 Adarb1 Cnot7 Cnot7 Ddb1 Ddb1 Ppara Ppara I79_022390 I79_022390 Ppih Ppih Nr5a2 Nr5a2 Top2a Top2a Pkn2 Pkn2 Tmem39a Tmem39a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (365 aa)
Hacd3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (371 aa)
PpiePeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
I79_011990Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (220 aa)
Larp1La-related protein 1. (571 aa)
Stau1Double-stranded RNA-binding protein Staufen-like 1. (489 aa)
I79_002227Vesicle-associated membrane protein-associated protein B. (252 aa)
Pde122',5'-phosphodiesterase 12. (606 aa)
Srpk2Serine/threonine-protein kinase SRPK2. (583 aa)
I79_008716Tripartite motif-containing protein 38. (304 aa)
I79_008349UV excision repair protein RAD23-like A. (316 aa)
AdarDouble-stranded RNA-specific adenosine deaminase. (1174 aa)
Fkbp6Peptidylprolyl isomerase. (327 aa)
Tmem39bTransmembrane protein 39B. (377 aa)
Adarb1Double-stranded RNA-specific editase 1. (701 aa)
Cnot7CCR4-NOT transcription complex subunit 7-like isoform 1. (285 aa)
Ddb1DNA damage-binding protein 1. (1140 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PpihPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (134 aa)
Nr5a2Nuclear receptor subfamily 5 group A member 2. (301 aa)
Top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1526 aa)
Pkn2Serine/threonine-protein kinase N2. (942 aa)
Tmem39aTransmembrane protein 39A. (486 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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