STRINGSTRING
I79_004403 I79_004403 Drd2 Drd2 Trafd1 Trafd1 Ythdf2 Ythdf2 Nfe2l2 Nfe2l2 Tyro3 Tyro3 Casp8 Casp8 Dusp10 Dusp10 Plcg2 Plcg2 Parp14 Parp14 I79_000675 I79_000675 I79_000806 I79_000806 I79_000871 I79_000871 I79_000872 I79_000872 I79_001015 I79_001015 I79_001279 I79_001279 I79_001341 I79_001341 Sin3a Sin3a I79_003514 I79_003514 Tlr9 Tlr9 Cnot7 Cnot7 Lep Lep I79_002785 I79_002785 I79_002696 I79_002696 I79_002662 I79_002662 Samhd1 Samhd1 I79_002266 I79_002266 I79_002265 I79_002265 I79_002263 I79_002263 Socs1 Socs1 Lyar Lyar Tnfaip3 Tnfaip3 Polr3d Polr3d Mmp12 Mmp12 Wnt5a Wnt5a Appl1 Appl1 I79_001405 I79_001405 Isg15 Isg15 I79_018387 I79_018387 Clec6a Clec6a I79_018653 I79_018653 I79_019425 I79_019425 I79_019488 I79_019488 CgPICR_017737 CgPICR_017737 I79_019913 I79_019913 I79_019922 I79_019922 Fgr Fgr Nlrx1 Nlrx1 H671_3g9402 H671_3g9402 Tlr8 Tlr8 Adam8 Adam8 Ube2k Ube2k Ereg Ereg I79_021138 I79_021138 I79_021139 I79_021139 I79_021153 I79_021153 I79_021300 I79_021300 I79_021301 I79_021301 I79_021555 I79_021555 I79_021556 I79_021556 I79_021561 I79_021561 I79_021590 I79_021590 I79_021762 I79_021762 I79_022003 I79_022003 Oas3 Oas3 I79_022023 I79_022023 I79_022092 I79_022092 I79_022187 I79_022187 I79_022189 I79_022189 I79_022945 I79_022945 Jhy Jhy I79_023189 I79_023189 I79_023218 I79_023218 Gbp5 Gbp5 I79_023355 I79_023355 I79_023356 I79_023356 Tkfc Tkfc Xrcc6 Xrcc6 I79_024082 I79_024082 I79_024153 I79_024153 I79_024249 I79_024249 Nmi Nmi I79_024691 I79_024691 I79_024862 I79_024862 Trim21 Trim21 I79_024961 I79_024961 I79_024962 I79_024962 I79_025191 I79_025191 I79_017613 I79_017613 I79_025305 I79_025305 I79_025514 I79_025514 Hpx Hpx Banf1 Banf1 Rnf185 Rnf185 I79_017371 I79_017371 Clec12b Clec12b Tlr4 Tlr4 I79_017064 I79_017064 Nlrc3 Nlrc3 I79_016618 I79_016618 I79_016547 I79_016547 I79_016293 I79_016293 I79_016292 I79_016292 N4bp1 N4bp1 I79_015916 I79_015916 Ttll12 Ttll12 Tasl Tasl I79_015466 I79_015466 I79_015453 I79_015453 Mettl3 Mettl3 I79_015062 I79_015062 Atg5 Atg5 Sting1 Sting1 Matr3 Matr3 PPARG PPARG Pla2g5 Pla2g5 I79_014258 I79_014258 Il21 Il21 Crk Crk Riok3 Riok3 I79_014025 I79_014025 Cactin Cactin Dnaja3 Dnaja3 I79_013640 I79_013640 Stat2 Stat2 Serping1 Serping1 Tap1 Tap1 I79_013172 I79_013172 Spata46 Spata46 I79_012974 I79_012974 Usp18 Usp18 Ythdf3 Ythdf3 Fadd Fadd Apoe Apoe I79_012636 I79_012636 Slc15a4 Slc15a4 Polr3b Polr3b Pqbp1 Pqbp1 Usp27x Usp27x Tomm70 Tomm70 Ifi35 Ifi35 I79_011712 I79_011712 I79_011711 I79_011711 Dhx58 Dhx58 Ncf1 Ncf1 Hexim1 Hexim1 Grn Grn Polr3g Polr3g Trex1 Trex1 Lamp1 Lamp1 I79_011017 I79_011017 I79_011011 I79_011011 Akirin2 Akirin2 I79_010477 I79_010477 Syk Syk Acod1 Acod1 Rasgrp1 Rasgrp1 I79_010155 I79_010155 Cgas Cgas I79_009350 I79_009350 Nlrc4 Nlrc4 I79_009072 I79_009072 Znfx1 Znfx1 IL12B IL12B Pspc1 Pspc1 I79_008231 I79_008231 C3 C3 I79_008088 I79_008088 Dcst1 Dcst1 Adar Adar I79_007841 I79_007841 I79_007699 I79_007699 I79_007634 I79_007634 Ikbke Ikbke I79_007462 I79_007462 Ap1g1 Ap1g1 I79_007301 I79_007301 Sfpq Sfpq Mul1 Mul1 I79_007088 I79_007088 I79_007070 I79_007070 Trim62 Trim62 I79_006509 I79_006509 I79_006508 I79_006508 I79_006506 I79_006506 Mbl2 Mbl2 Il18rap Il18rap Cdc37 Cdc37 Med1 Med1 Nod2 Nod2 I79_005198 I79_005198 Xrcc5 Xrcc5 I79_004904 I79_004904 Hsp90aa1 Hsp90aa1 Polr3c Polr3c I79_004486 I79_004486
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
Drd2D(2) dopamine receptor. (274 aa)
Trafd1TRAF-type zinc finger domain-containing protein 1. (570 aa)
Ythdf2YTH domain family protein 2. (529 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
Tyro3Tyrosine-protein kinase receptor TYRO3. (816 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Dusp10Dual specificity protein phosphatase 10. (482 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
Parp14Poly [ADP-ribose] polymerase. (1786 aa)
I79_000675Poly [ADP-ribose] polymerase 9. (337 aa)
I79_000806Heat shock cognate protein HSP 90-beta. (102 aa)
I79_000871Mannan-binding lectin serine protease 1; Belongs to the peptidase S1 family. (706 aa)
I79_000872Mannan-binding lectin serine protease 1. (205 aa)
I79_001015Low-density lipoprotein receptor-related protein 8. (764 aa)
I79_001279Hsp90 co-chaperone Cdc37. (245 aa)
I79_001341Killer cell lectin-like receptor subfamily B member 1A. (133 aa)
Sin3aPaired amphipathic helix protein Sin3a. (1274 aa)
I79_003514T-cell surface protein tactile. (353 aa)
Tlr9Toll-like receptor 9. (1239 aa)
Cnot7CCR4-NOT transcription complex subunit 7-like isoform 1. (285 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
I79_002785Beta-arrestin-2. (65 aa)
I79_002696Phosphoinositide 3-kinase regulatory subunit 6. (395 aa)
I79_002662Interleukin-1 receptor-associated kinase 3. (537 aa)
Samhd1SAM domain and HD domain-containing protein 1. (670 aa)
I79_002266Serpin B9; Belongs to the serpin family. (262 aa)
I79_002265Serpin B9; Belongs to the serpin family. (375 aa)
I79_002263Serpin B9; Belongs to the serpin family. (339 aa)
Socs1Suppressor of cytokine signaling 1. (93 aa)
LyarCell growth-regulating nucleolar protein. (382 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
Polr3dDNA-directed RNA polymerase III subunit RPC4. (398 aa)
Mmp12Macrophage metalloelastase. (464 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Appl1DCC-interacting protein 13-alpha. (664 aa)
I79_001405Lymphocyte activation gene 3 protein. (345 aa)
Isg15Ubiquitin-like protein ISG15-like protein. (156 aa)
I79_018387RNA-binding protein 14. (500 aa)
Clec6aC-type lectin domain family 6 member A. (167 aa)
I79_018653Heat shock protein HSP 90-beta. (131 aa)
I79_019425Apoptosis-associated speck-like protein containing a CARD. (192 aa)
I79_019488Non-POU domain-containing octamer-binding protein. (613 aa)
CgPICR_017737Lysosome-associated membrane glycoprotein 1. (403 aa)
I79_019913Cell adhesion molecule 1. (390 aa)
I79_019922Serine/threonine-protein kinase TBK1. (421 aa)
FgrTyrosine-protein kinase. (435 aa)
Nlrx1NLR family member X1. (2478 aa)
H671_3g9402Interferon regulatory factor 7. (473 aa)
Tlr8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1027 aa)
Adam8Disintegrin and metalloproteinase domain-containing protein 8. (936 aa)
Ube2kUbiquitin-conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
EregProepiregulin. (162 aa)
I79_021138Heat shock protein HSP 90-beta. (90 aa)
I79_021139Heat shock protein HSP 90-beta. (113 aa)
I79_021153Putative ATP-dependent RNA helicase DHX58. (89 aa)
I79_021300Poly [ADP-ribose] polymerase. (324 aa)
I79_021301Poly [ADP-ribose] polymerase 9. (112 aa)
I79_021555Killer cell lectin-like receptor subfamily F member 1. (109 aa)
I79_021556C-type lectin domain family 2 member D11. (210 aa)
I79_021561C-type lectin domain family 2 member D11. (262 aa)
I79_021590Heat shock protein HSP 90-beta. (121 aa)
I79_021762Tripartite motif-containing protein 30. (513 aa)
I79_0220032'-5'-oligoadenylate synthetase 3. (365 aa)
Oas32'-5'-oligoadenylate synthetase 3. (685 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
I79_022092Mannan-binding lectin serine protease 2. (185 aa)
I79_022187Tripartite motif-containing protein 30. (495 aa)
I79_022189Tripartite motif-containing protein 6. (488 aa)
I79_022945Immunity-related GTPase family M protein. (285 aa)
JhyCytotoxic and regulatory T-cell molecule. (334 aa)
I79_023189Ficolin-1. (274 aa)
I79_023218Interferon regulatory factor 3. (377 aa)
Gbp5Guanylate-binding protein 5. (182 aa)
I79_023355Ubiquitin carboxyl-terminal hydrolase 29; Belongs to the peptidase C19 family. (535 aa)
I79_023356Ubiquitin carboxyl-terminal hydrolase 29; Belongs to the peptidase C19 family. (325 aa)
TkfcBifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (Cyclizing). (578 aa)
Xrcc6ATP-dependent DNA helicase 2 subunit 1. (608 aa)
I79_024082Heat shock protein HSP 90-beta. (166 aa)
I79_024153Ficolin-2. (290 aa)
I79_024249Poly [ADP-ribose] polymerase 9. (106 aa)
NmiN-myc-interactor. (303 aa)
I79_024691Poly [ADP-ribose] polymerase 9. (187 aa)
I79_024862Tyrosine-protein kinase TXK. (122 aa)
Trim2152 kDa Ro protein. (463 aa)
I79_024961Uncharacterized protein C19orf29-like. (328 aa)
I79_024962Uncharacterized protein C19orf29-like. (171 aa)
I79_025191Tripartite motif-containing protein 6. (212 aa)
I79_017613DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa)
I79_025305UPF0389 protein FAM162A. (213 aa)
I79_025514NKG2D ligand 1. (218 aa)
HpxHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (461 aa)
Banf1Barrier-to-autointegration factor. (89 aa)
Rnf185RING finger protein 185. (134 aa)
I79_017371NKG2-A/NKG2-B type II integral membrane protein. (100 aa)
Clec12bC-type lectin domain family 12 member B. (177 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
I79_017064Tripartite motif-containing protein 6. (58 aa)
Nlrc3Protein NLRC3. (975 aa)
I79_016618Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (470 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
I79_016293Heat shock protein HSP 90-alpha 1. (135 aa)
I79_016292Heat shock protein HSP 90-alpha. (205 aa)
N4bp1NEDD4-binding protein 1. (811 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Ttll12Tubulin--tyrosine ligase-like protein 12. (655 aa)
TaslUncharacterized protein CXorf21-like. (216 aa)
I79_015466Ubiquitin carboxyl-terminal hydrolase 27. (176 aa)
I79_015453C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
Mettl3N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
I79_015062Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (390 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (147 aa)
Sting1Transmembrane protein 173. (315 aa)
Matr3Matrin-3. (847 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Pla2g5Phospholipase A(2). (137 aa)
I79_014258Cysteine dioxygenase. (99 aa)
Il21Interleukin-21. (67 aa)
CrkProto-oncogene C-crk. (327 aa)
Riok3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
I79_014025Zinc finger CCHC domain-containing protein 3. (270 aa)
CactinUncharacterized protein C19orf29-like. (425 aa)
Dnaja3DnaJ-like subfamily A member 3, mitochondrial. (453 aa)
I79_013640Heat shock protein HSP 90-alpha. (249 aa)
Stat2Signal transducer and activator of transcription. (806 aa)
Serping1Plasma protease C1 inhibitor; Belongs to the serpin family. (177 aa)
Tap1Antigen peptide transporter 1. (725 aa)
I79_013172H-2 class I histocompatibility antigen, L-D alpha chain; Belongs to the MHC class I family. (209 aa)
Spata46Uncharacterized protein C1orf111-like. (290 aa)
I79_012974Putative ubiquitin carboxyl-terminal hydrolase 41. (87 aa)
Usp18Ubl carboxyl-terminal hydrolase 18. (60 aa)
Ythdf3YTH domain family protein 3. (588 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ApoeApolipoprotein E. (313 aa)
I79_012636Poliovirus receptor. (346 aa)
Slc15a4Solute carrier family 15 member 4. (455 aa)
Polr3bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
Pqbp1Polyglutamine-binding protein 1. (265 aa)
Usp27xUbiquitin carboxyl-terminal hydrolase 27; Belongs to the peptidase C19 family. (438 aa)
Tomm70Mitochondrial import receptor subunit TOM70. (384 aa)
Ifi35Interferon-induced 35 kDa protein-like. (286 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
Dhx58Putative ATP-dependent RNA helicase DHX58. (56 aa)
Ncf1Neutrophil cytosol factor 1. (303 aa)
Hexim1Protein HEXIM1. (356 aa)
GrnGranulins. (592 aa)
Polr3gDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (227 aa)
Trex1Three prime repair exonuclease 1. (320 aa)
Lamp1Lysosome-associated membrane glycoprotein 1. (370 aa)
I79_011017Immunity-related GTPase family M protein. (341 aa)
I79_011011E3 ubiquitin-protein ligase TRIM 41. (258 aa)
Akirin2Akirin-2. (112 aa)
I79_010477Protein NLRC5. (1513 aa)
SykTyrosine-protein kinase. (611 aa)
Acod1Immune-responsive gene 1 protein. (290 aa)
Rasgrp1RAS guanyl-releasing protein 1. (787 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
CgasUncharacterized protein C6orf150. (512 aa)
I79_009350Toll/interleukin-1 receptor domain-containing adapter protein. (245 aa)
Nlrc4NLR family CARD domain-containing protein 4. (857 aa)
I79_009072NFX1-type zinc finger-containing protein 1. (416 aa)
Znfx1NFX1-type zinc finger-containing protein 1. (747 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
Pspc1Paraspeckle component 1. (522 aa)
I79_008231Proto-oncogene vav. (879 aa)
C3Complement C3. (1626 aa)
I79_008088Heat shock protein HSP 90-beta. (412 aa)
Dcst1DC-STAMP domain-containing protein 1. (642 aa)
AdarDouble-stranded RNA-specific adenosine deaminase. (1174 aa)
I79_007841Z-DNA-binding protein 1. (235 aa)
I79_007699GTPase IMAP family member 5. (344 aa)
I79_007634Heat shock protein HSP 90-beta. (176 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon. (640 aa)
I79_007462Poly [ADP-ribose] polymerase 14. (125 aa)
Ap1g1AP-1 complex subunit gamma. (822 aa)
I79_007301Tripartite motif-containing protein 56. (1274 aa)
SfpqSplicing factor, proline-and glutamine-rich. (351 aa)
Mul1Mitochondrial ubiquitin ligase activator of NFKB 1. (321 aa)
I79_007088Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (870 aa)
I79_007070Serine/threonine-protein kinase TBK1. (271 aa)
Trim62Tripartite motif-containing protein 62. (347 aa)
I79_006509Interferon-activable protein 204. (781 aa)
I79_006508Interferon-activable protein 203. (428 aa)
I79_006506Interferon-inducible protein AIM2. (352 aa)
Mbl2Mannose-binding protein C. (250 aa)
Il18rapInterleukin-18 receptor accessory protein. (431 aa)
Cdc37Hsp90 co-chaperone Cdc37. (379 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2. (989 aa)
I79_005198Cochlin. (510 aa)
Xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
I79_004904NKG2D ligand 4. (293 aa)
Hsp90aa1Heat shock protein HSP 90-alpha. (332 aa)
Polr3cRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (533 aa)
I79_004486CD160 antigen. (151 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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