(32 nodes) Myoblast differentiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Igf1	Insulin-like growth factor I. (75 aa)
	Isl1	Insulin gene enhancer protein ISL-1. (257 aa)
	I79_003941	Multiple epidermal growth factor-like domains 10. (800 aa)
	I79_003100	Myocardin. (371 aa)
	Sox15	Protein SOX-15. (149 aa)
	I79_001364	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
	Lgals1	Galectin. (135 aa)
	Tbxt	Brachyury protein. (223 aa)
	Mapk12	Mitogen-activated protein kinase. (380 aa)
	Tcf7l2	Transcription factor 7-like 1. (73 aa)
	Epas1	Endothelial PAS domain-containing protein 1. (878 aa)
	Grem1	Gremlin-1. (117 aa)
	I79_021538	Brachyury protein. (242 aa)
	I79_020783	Transcription factor 7-like 2. (451 aa)
	Hinfp	Histone H4 transcription factor. (513 aa)
	Rest	RE1-silencing transcription factor. (1047 aa)
	Wnt10b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	I79_017350	Myoblast determination protein 1. (112 aa)
	Dicer1	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
	Itgb1	Integrin beta; Belongs to the integrin beta chain family. (798 aa)
	Srf	Serum response factor. (361 aa)
	Plekhm3	Pleckstrin-likey domain-containing family M member 3. (753 aa)
	I79_014451	Pro-neuregulin-1, membrane-bound isoform. (639 aa)
	Rb1	Retinoblastoma-associated protein. (302 aa)
	I79_011479	Muscleblind-like protein 1. (381 aa)
	I79_010136	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
	I79_009796	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
	Sdc1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (285 aa)
	Ddx5	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (615 aa)
	Tbx2	T-box transcription factor TBX2. (234 aa)
	Gpx1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ddx5	I79_017350	G3HCT4	G3I1T1	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Myoblast determination protein 1.	0.480
Grem1	I79_006225	G3ID48	G3H796	Gremlin-1.	Sonic hedgehog protein.	0.455
I79_001364	I79_006225	G3GUK2	G3H796	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Sonic hedgehog protein.	0.425
I79_001364	Igf1	G3GUK2	G3H672	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Insulin-like growth factor I.	0.690
I79_001364	Sdc1	G3GUK2	G3HDJ3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.670
I79_003100	Srf	G3GZ48	G3HYT2	Myocardin.	Serum response factor.	0.968
I79_006225	Grem1	G3H796	G3ID48	Sonic hedgehog protein.	Gremlin-1.	0.455
I79_006225	I79_001364	G3H796	G3GUK2	Sonic hedgehog protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.425
I79_010136	Tbx2	G3HHN2	G3H9E9	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor TBX2.	0.441
I79_010136	Wnt10b	G3HHN2	G3I6J3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.495
I79_017350	Ddx5	G3I1T1	G3HCT4	Myoblast determination protein 1.	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	0.480
I79_017350	Igf1	G3I1T1	G3H672	Myoblast determination protein 1.	Insulin-like growth factor I.	0.565
I79_017350	Mapk12	G3I1T1	G3I2V4	Myoblast determination protein 1.	Mitogen-activated protein kinase.	0.513
I79_017350	Srf	G3I1T1	G3HYT2	Myoblast determination protein 1.	Serum response factor.	0.564
Igf1	I79_001364	G3H672	G3GUK2	Insulin-like growth factor I.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.690
Igf1	I79_017350	G3H672	G3I1T1	Insulin-like growth factor I.	Myoblast determination protein 1.	0.565
Isl1	Tbx2	G3H207	G3H9E9	Insulin gene enhancer protein ISL-1.	T-box transcription factor TBX2.	0.523
Isl1	Tbxt	G3H207	G3I4D0	Insulin gene enhancer protein ISL-1.	Brachyury protein.	0.426
Itgb1	Sdc1	G3HZ55	G3HDJ3	Integrin beta; Belongs to the integrin beta chain family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.483
Itgb1	Srf	G3HZ55	G3HYT2	Integrin beta; Belongs to the integrin beta chain family.	Serum response factor.	0.562