STRINGSTRING
Mstn Mstn I79_015084 I79_015084 Gabbr1 Gabbr1 Htr1b Htr1b Sod2 Sod2 Gk Gk Itpr2 Itpr2 H671_3g9558 H671_3g9558 I79_015916 I79_015916 I79_016007 I79_016007 St6gal1 St6gal1 Adipoq Adipoq Nr0b2 Nr0b2 Ehmt2 Ehmt2 Tnf Tnf H671_1g1119 H671_1g1119 Glra3 Glra3 I79_016677 I79_016677 Nqo1 Nqo1 Pth Pth I79_017077 I79_017077 Psmd14 Psmd14 Tlr4 Tlr4 I79_017273 I79_017273 Got2 Got2 Eif4g1 Eif4g1 Sdf4 Sdf4 Fgf19 Fgf19 I79_018567 I79_018567 I79_018586 I79_018586 Cd14 Cd14 Adcyap1 Adcyap1 I79_018654 I79_018654 I79_010863 I79_010863 Phb Phb Grin3a Grin3a Ppp3r2 Ppp3r2 Igf1r Igf1r Grin2b Grin2b I79_011711 I79_011711 Fyn Fyn I79_012336 I79_012336 Hmgcs2 Hmgcs2 Ggh Ggh Myd88 Myd88 I79_013438 I79_013438 Tbxa2r Tbxa2r Kcnmb1 Kcnmb1 IL2 IL2 Unc79 Unc79 I79_014940 I79_014940 Cdk1 Cdk1 I79_015041 I79_015041 I79_015056 I79_015056 Nppc Nppc I79_025230 I79_025230 I79_025333 I79_025333 I79_025355 I79_025355 I79_025443 I79_025443 Cpt1a Cpt1a Csf3 Csf3 I79_025720 I79_025720 Myc Myc Dbh Dbh I79_018785 I79_018785 Tufm Tufm Prkcb Prkcb G6pd G6pd Rgs19 Rgs19 H671_xg20331 H671_xg20331 Vcam1 Vcam1 I79_021745 I79_021745 I79_021789 I79_021789 cytb cytb NADH4 NADH4 I79_022390 I79_022390 Ppara Ppara I79_022612 I79_022612 Tyms Tyms I79_022685 I79_022685 I79_022712 I79_022712 I79_023022 I79_023022 Arsa Arsa Ntrk3 Ntrk3 Bak1 Bak1 Ccnd1 Ccnd1 Casp8 Casp8 Gata3 Gata3 Trh Trh I79_000677 I79_000677 Cldn1 Cldn1 CgPICR_003438 CgPICR_003438 I79_001072 I79_001072 Oprm1 Oprm1 I79_001236 I79_001236 Tnfrsf1a Tnfrsf1a I79_001592 I79_001592 Prkce Prkce I79_001764 I79_001764 Grin2a Grin2a Abat Abat Vhl Vhl Ogg1 Ogg1 Slc2a4 Slc2a4 Dmap1 Dmap1 Cat Cat Lep Lep Lct Lct I79_003549 I79_003549 Tacr1 Tacr1 I79_003843 I79_003843 Rpl15 Rpl15 Eif4ebp1 Eif4ebp1 Slc10a1 Slc10a1 Drd2 Drd2 I79_004403 I79_004403 I79_004452 I79_004452 Ca3 Ca3 Setdb1 Setdb1 Crhbp Crhbp I79_005007 I79_005007 Rgs2 Rgs2 Glra1 Glra1 Tjp1 Tjp1 Adcy7 Adcy7 Actc1 Actc1 Igf1 Igf1 I79_006225 I79_006225 Adipor2 Adipor2 Eps8 Eps8 Sirt1 Sirt1 I79_007391 I79_007391 Atp5f1a Atp5f1a Chrnb2 Chrnb2 Prkca Prkca Cyp7a1 Cyp7a1 Hoxa1 Hoxa1 Eef1b2 Eef1b2 I79_008985 I79_008985 Kcnc2 Kcnc2 Cldn5 Cldn5 Actr2 Actr2 I79_023930 I79_023930 I79_024097 I79_024097 Fgfr2 Fgfr2 I79_024271 I79_024271 I79_024481 I79_024481 I79_024765 I79_024765 Adh7 Adh7 CgPICR_017246 CgPICR_017246 Cldn18 Cldn18 I79_009728 I79_009728 Glra2 Glra2 Oxct1 Oxct1 Prkaa1 Prkaa1 Polb Polb I79_010155 I79_010155 Hdac2 Hdac2 Alad Alad Tp53inp1 Tp53inp1 Rps6kb1 Rps6kb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MstnGrowth/differentiation factor 8. (295 aa)
I79_015084Gamma-aminobutyric acid type B receptor subunit 1. (281 aa)
Gabbr1Gamma-aminobutyric acid type B receptor subunit 1. (401 aa)
Htr1b5-hydroxytryptamine receptor 1B. (386 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
GkGlycerol kinase. (273 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (470 aa)
H671_3g9558Tyrosine 3-monooxygenase-like protein. (542 aa)
I79_015916Insulin-like growth factor II. (155 aa)
I79_016007Cytochrome b-245 heavy chain. (396 aa)
St6gal1Beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (402 aa)
AdipoqAdiponectin. (248 aa)
Nr0b2Nuclear receptor subfamily 0 group B member 2. (260 aa)
Ehmt2Histone-lysine N-methyltransferase, H3 lysine-9 specific 3. (661 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
H671_1g111915-hydroxyprostaglandin dehydrogenase [NAD+]-like protein. (208 aa)
Glra3Glycine receptor subunit alpha-3. (197 aa)
I79_016677Glycine receptor subunit alpha-3. (147 aa)
Nqo1NAD(P)H dehydrogenase [quinone] 1. (274 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
I79_017077Acetoacetyl-CoA synthetase. (634 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
I79_017273Protein kinase C alpha type. (128 aa)
Got2Aspartate aminotransferase. (430 aa)
Eif4g1Eukaryotic translation initiation factor 4 gamma 1. (1590 aa)
Sdf445 kDa calcium-binding protein. (355 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
I79_018567Amine oxidase. (480 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
Cd14Monocyte differentiation antigen CD14. (309 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide-like protein. (176 aa)
I79_018654Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
I79_010863Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (533 aa)
PhbProhibitin. (272 aa)
Grin3aGlutamate [NMDA] receptor subunit 3A. (759 aa)
Ppp3r2Glutamate [NMDA] receptor subunit 3A. (384 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
Grin2bGlutamate [NMDA] receptor subunit epsilon-2. (1373 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
FynProto-oncogene tyrosine-protein kinase Fyn. (232 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
GghFolate gamma-glutamyl hydrolase. (271 aa)
Myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
I79_013438Prohibitin. (132 aa)
Tbxa2rThromboxane A2 receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
Kcnmb1Calcium-activated potassium channel subunit beta-1. (191 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
Unc79Protein unc-79-like. (223 aa)
I79_014940Prohibitin. (85 aa)
Cdk1Cell division control protein 2-like; Belongs to the protein kinase superfamily. (297 aa)
I79_015041Thymidylate synthase. (192 aa)
I79_015056Neuronal acetylcholine receptor subunit alpha-7. (412 aa)
NppcC-type natriuretic peptide. (126 aa)
I79_025230Alcohol dehydrogenase 1. (331 aa)
I79_025333Alcohol dehydrogenase 1. (220 aa)
I79_025355Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (325 aa)
I79_025443Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (229 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
Csf3Granulocyte colony-stimulating factor. (208 aa)
I79_025720Corticotropin-releasing factor receptor 1. (134 aa)
MycMyc proto-oncogene protein. (281 aa)
DbhDopamine beta-hydroxylase. (117 aa)
I79_018785Retinoic acid receptor alpha. (484 aa)
TufmElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (452 aa)
PrkcbNon-specific serine/threonine protein kinase. (544 aa)
G6pdGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (624 aa)
Rgs19Regulator of G-protein signaling 19. (209 aa)
H671_xg20331Eukaryotic translation initiation factor 4 gamma 1 isoform 1. (309 aa)
Vcam1Vascular cell adhesion protein 1. (220 aa)
I79_021745Ubiquitin carboxyl-terminal hydrolase 46. (333 aa)
I79_021789NT-3 growth factor receptor. (389 aa)
cytbCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
NADH4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022612Actin-related protein 2; Belongs to the actin family. (158 aa)
TymsThymidylate synthase-like protein. (307 aa)
I79_022685Dopamine beta-hydroxylase. (534 aa)
I79_022712Glutamate [NMDA] receptor subunit zeta-1. (998 aa)
I79_023022UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (218 aa)
ArsaArylsulfatase A. (518 aa)
Ntrk3Tyrosine-protein kinase receptor. (226 aa)
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
Casp8Caspase-8; Belongs to the peptidase C14A family. (481 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
TrhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (247 aa)
I79_000677Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
Cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CgPICR_003438C-C motif chemokine. (143 aa)
I79_001072C-C motif chemokine. (97 aa)
Oprm1Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (394 aa)
I79_001236Bile salt export pump. (1096 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
PrkceProtein kinase C epsilon type. (137 aa)
I79_001764Glutamate [NMDA] receptor subunit epsilon-1. (147 aa)
Grin2aGlutamate [NMDA] receptor subunit epsilon-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1307 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
VhlVon Hippel-Lindau disease tumor suppressor. (134 aa)
Ogg1N-glycosylase/DNA lyase. (335 aa)
Slc2a4Solute carrier family 2, facilitated glucose transporter member 4. (90 aa)
Dmap1DNA methyltransferase 1-associated protein 1. (468 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LctDNA helicase; Belongs to the MCM family. (2669 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Tacr1Substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
I79_003843Actin-related protein 2. (86 aa)
Rpl15Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
Eif4ebp1Eukaryotic translation initiation factor 4E-binding protein 1. (117 aa)
Slc10a1Sodium/bile acid cotransporter. (317 aa)
Drd2D(2) dopamine receptor. (274 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
I79_004452Prohibitin. (131 aa)
Ca3Carbonic anhydrase 3. (245 aa)
Setdb1Histone-lysine N-methyltransferase SETDB1. (1227 aa)
CrhbpCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
I79_005007Solute carrier family 23 member 2. (933 aa)
Rgs2Regulator of G-protein signaling 2. (207 aa)
Glra1Glycine receptor subunit alpha-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (413 aa)
Tjp1Tight junction protein ZO-1. (762 aa)
Adcy7Adenylate cyclase type 7. (694 aa)
Actc1Actin, alpha cardiac muscle 1. (377 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Adipor2Adiponectin receptor protein 2. (386 aa)
Eps8Epidermal growth factor receptor kinase substrate 8. (821 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007391ATP synthase subunit alpha, mitochondrial. (65 aa)
Atp5f1aATP synthase subunit alpha, mitochondrial. (285 aa)
Chrnb2Neuronal acetylcholine receptor subunit beta-2. (495 aa)
PrkcaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (487 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
Hoxa1Homeobox protein Hox-A1. (334 aa)
Eef1b2Elongation factor 1-beta; Belongs to the EF-1-beta/EF-1-delta family. (225 aa)
I79_008985Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (237 aa)
Kcnc2Potassium voltage-gated channel subfamily C member 2. (247 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
Actr2Actin-related protein 2; Belongs to the actin family. (178 aa)
I79_023930Actin-related protein 2. (139 aa)
I79_024097Vascular cell adhesion protein 1. (225 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_024271NT-3 growth factor receptor. (114 aa)
I79_024481Prohibitin. (274 aa)
I79_024765Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (216 aa)
Adh7Alcohol dehydrogenase class 4 mu/sigma chain. (362 aa)
CgPICR_017246Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
Cldn18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
I79_009728Thromboxane-A synthase; Belongs to the cytochrome P450 family. (453 aa)
Glra2Glycine receptor subunit alpha-2. (161 aa)
Oxct1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
Prkaa1Non-specific serine/threonine protein kinase. (477 aa)
PolbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
AladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
Tp53inp1Tumor protein p53-inducible nuclear protein 1. (239 aa)
Rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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