STRINGSTRING
Lrp5 Lrp5 Htr2a Htr2a I79_018131 I79_018131 I79_017450 I79_017450 Zbtb16 Zbtb16 I79_017381 I79_017381 Gdf3 Gdf3 Htr2c Htr2c Dkkl1 Dkkl1 Trpm4 Trpm4 Mapk14 Mapk14 Napepld Napepld Cmklr1 Cmklr1 PPARG PPARG I79_014483 I79_014483 I79_014474 I79_014474 I79_013817 I79_013817 Snai2 Snai2 I79_013013 I79_013013 Xbp1 Xbp1 Tfe3 Tfe3 Axin2 Axin2 Noct Noct Crebl2 Crebl2 I79_011789 I79_011789 Stk4 Stk4 Pim1 Pim1 Stk3 Stk3 Zfp36 Zfp36 I79_006981 I79_006981 Sh3pxd2b Sh3pxd2b Six1 Six1 Lmo3 Lmo3 Prdm16 Prdm16 I79_025027 I79_025027 I79_025026 I79_025026 I79_024533 I79_024533 Hnrnpu Hnrnpu Lpl Lpl Fndc3b Fndc3b I79_005864 I79_005864 Igf1 Igf1 I79_005573 I79_005573 Klf5 Klf5 Akt1 Akt1 Zfp36l1 Zfp36l1 Wdfy2 Wdfy2 I79_002654 I79_002654 Asxl2 Asxl2 Ptgs2 Ptgs2 Medag Medag Ccdc3 Ccdc3 Tph1 Tph1 I79_024173 I79_024173 I79_022994 I79_022994 I79_006895 I79_006895 I79_007707 I79_007707 Bmp7 Bmp7 Zbtb7b Zbtb7b Rreb1 Rreb1 Zc3h12a Zc3h12a Sfrp1 Sfrp1 I79_006675 I79_006675 Wnt5b Wnt5b Sav1 Sav1 Vstm2a Vstm2a Znf385a Znf385a I79_010314 I79_010314 I79_018885 I79_018885 I79_018750 I79_018750 Aamdc Aamdc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
Htr2a5-hydroxytryptamine receptor 2A. (264 aa)
I79_0181315-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (237 aa)
I79_017450Zinc finger and BTB domain-containing protein 16. (236 aa)
Zbtb16Zinc finger and BTB domain-containing protein 16. (423 aa)
I79_017381Synapse-associated protein 1. (313 aa)
Gdf3Growth/differentiation factor 3. (361 aa)
Htr2c5-hydroxytryptamine receptor 2C. (317 aa)
Dkkl1Dickkopf-like protein 1. (230 aa)
Trpm4Transient receptor potential cation channel subfamily M member 4. (315 aa)
Mapk14Mitogen-activated protein kinase. (349 aa)
NapepldN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D. (236 aa)
Cmklr1Chemokine receptor-like 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_014483Serine/threonine-protein kinase 3. (118 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
Snai2Zinc finger protein SNAI2-like protein. (268 aa)
I79_013013Transcription factor SOX-13. (600 aa)
Xbp1X-box binding protein 1 isoform 1. (330 aa)
Tfe3Transcription factor E3. (574 aa)
Axin2Axin-2. (809 aa)
NoctNocturnin. (365 aa)
Crebl2cAMP-responsive element-binding protein-like 2. (79 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
Pim1Proto-oncogene serine/threonine-protein kinase Pim-1. (250 aa)
Stk3Serine/threonine-protein kinase 3. (260 aa)
Zfp36Tristetraproline. (315 aa)
I79_006981G-protein coupled receptor 120. (318 aa)
Sh3pxd2bSH3 and PX domain-containing protein 2B. (880 aa)
Six1Homeobox protein SIX1. (284 aa)
Lmo3LIM domain only protein 3. (149 aa)
Prdm16PR domain zinc finger protein 16. (274 aa)
I79_025027PR domain zinc finger protein 16. (86 aa)
I79_025026PR domain zinc finger protein 16. (409 aa)
I79_024533Tryptophan 5-hydroxylase 1. (131 aa)
HnrnpuHeterogeneous nuclear ribonucleoprotein U. (512 aa)
LplLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
Fndc3bFibronectin type III domain-containing protein 3B. (1203 aa)
I79_005864Histone-arginine methyltransferase CARM1. (94 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
Klf5Krueppel-like factor 5. (366 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Zfp36l1Butyrate response factor 1. (338 aa)
Wdfy2WD repeat and FYVE domain-containing protein 2. (372 aa)
I79_002654Wnt inhibitory factor 1. (347 aa)
Asxl2Putative Polycomb group protein ASXL2. (1421 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
MedagMEDAG. (303 aa)
Ccdc3Coiled-coil domain-containing protein 3. (272 aa)
Tph1Tryptophan 5-hydroxylase 1. (115 aa)
I79_024173PR domain zinc finger protein 16. (77 aa)
I79_022994Dapper-like 1. (530 aa)
I79_006895Fibronectin type III domain-containing protein 5. (244 aa)
I79_007707Retinoic acid receptor responder protein 2. (144 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Zbtb7bZinc finger and BTB domain-containing protein 7B. (543 aa)
Rreb1Ras-responsive element-binding protein 1. (1748 aa)
Zc3h12aRibonuclease ZC3H12A. (577 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_006675Secreted frizzled-related protein 3. (286 aa)
Wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (371 aa)
Sav1Protein salvador-like 1. (210 aa)
Vstm2aV-set and transmembrane domain-containing protein 2A. (236 aa)
Znf385aZinc finger protein 385A. (366 aa)
I79_010314Ecotropic virus integration site 1 protein. (947 aa)
I79_018885Transmembrane protein 64. (105 aa)
I79_018750Phosphatidate cytidylyltransferase; Belongs to the CDS family. (367 aa)
AamdcUPF0366 protein C11orf67-like. (109 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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