(14 nodes) Positive regulation of glycogen biosynthetic process network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_015916	Insulin-like growth factor II. (155 aa)
	I79_015895	Sorbin and SH3 domain-containing protein 1. (852 aa)
	Epm2aip1	EPM2A-interacting protein 1. (606 aa)
	Dyrk2	Dual specificity tyrosine-phosphorylation-regulated kinase 2. (528 aa)
	Akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	Igf1	Insulin-like growth factor I. (75 aa)
	C1qtnf2	Complement C1q tumor necrosis factor-related protein 2. (285 aa)
	I79_009443	Steroid hormone receptor ERR2. (475 aa)
	Gck	Phosphotransferase. (465 aa)
	Akt2	Non-specific serine/threonine protein kinase. (200 aa)
	Insr	Insulin receptor. (114 aa)
	Irs2	Insulin receptor substrate 2. (465 aa)
	Irs1	Insulin receptor substrate 1. (1233 aa)
	Pth	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akt1	Akt2	G3H397	G3HNQ3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.969
Akt1	I79_015916	G3H397	G3HXZ9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin-like growth factor II.	0.443
Akt1	Igf1	G3H397	G3H672	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin-like growth factor I.	0.710
Akt1	Irs1	G3H397	G3IDC4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 1.	0.724
Akt1	Irs2	G3H397	G3IKD0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 2.	0.587
Akt2	Akt1	G3HNQ3	G3H397	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.969
Akt2	Igf1	G3HNQ3	G3H672	Non-specific serine/threonine protein kinase.	Insulin-like growth factor I.	0.530
Akt2	Irs1	G3HNQ3	G3IDC4	Non-specific serine/threonine protein kinase.	Insulin receptor substrate 1.	0.658
Akt2	Irs2	G3HNQ3	G3IKD0	Non-specific serine/threonine protein kinase.	Insulin receptor substrate 2.	0.654
Gck	Irs1	G3HMA6	G3IDC4	Phosphotransferase.	Insulin receptor substrate 1.	0.403
Gck	Irs2	G3HMA6	G3IKD0	Phosphotransferase.	Insulin receptor substrate 2.	0.412
I79_015916	Akt1	G3HXZ9	G3H397	Insulin-like growth factor II.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.443
I79_015916	Igf1	G3HXZ9	G3H672	Insulin-like growth factor II.	Insulin-like growth factor I.	0.734
I79_015916	Insr	G3HXZ9	G3HWV6	Insulin-like growth factor II.	Insulin receptor.	0.884
I79_015916	Irs1	G3HXZ9	G3IDC4	Insulin-like growth factor II.	Insulin receptor substrate 1.	0.587
I79_015916	Irs2	G3HXZ9	G3IKD0	Insulin-like growth factor II.	Insulin receptor substrate 2.	0.587
Igf1	Akt1	G3H672	G3H397	Insulin-like growth factor I.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.710
Igf1	Akt2	G3H672	G3HNQ3	Insulin-like growth factor I.	Non-specific serine/threonine protein kinase.	0.530
Igf1	I79_015916	G3H672	G3HXZ9	Insulin-like growth factor I.	Insulin-like growth factor II.	0.734
Igf1	Insr	G3H672	G3HWV6	Insulin-like growth factor I.	Insulin receptor.	0.997