(33 nodes) Negative regulation of Notch signaling pathway network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

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protein homology

Your Input:
	I79_006052	Tetraspanin-15. (330 aa)
	I79_015033	Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
	Cdk3	Cell division protein kinase 3; Belongs to the protein kinase superfamily. (322 aa)
	I79_013395	Matrix metalloproteinase-14. (539 aa)
	Dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
	I79_011998	GDP-fucose transporter 1. (178 aa)
	I79_010785	Delta-like protein 3. (388 aa)
	I79_010588	Cyclin-C. (246 aa)
	Tcim	Uncharacterized protein C8orf4-like. (106 aa)
	Kctd10	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3. (312 aa)
	Gata2	Endothelial transcription factor GATA-2. (480 aa)
	I79_008640	NF-kappa-B inhibitor alpha. (90 aa)
	Dlx2	Homeobox protein DLX-2. (347 aa)
	Lfng	Beta-1,3-N-acetylglucosaminyltransferase. (378 aa)
	Rfng	Beta-1,3-N-acetylglucosaminyltransferase radical fringe. (229 aa)
	Slc35c1	GDP-fucose transporter 1. (365 aa)
	Dlk2	Protein delta-like 2. (382 aa)
	Cbfa2t2	Protein CBFA2T2. (574 aa)
	I79_008639	NF-kappa-B inhibitor alpha. (52 aa)
	Dlx1	Homeobox protein DLX-1. (255 aa)
	Bcl6	B-cell lymphoma 6 protein-like. (707 aa)
	Bmp7	Bone morphogenetic protein 7. (430 aa)
	Arrb1	Beta-arrestin-1. (422 aa)
	I79_024292	EGF-like domain-containing protein 7. (238 aa)
	Chac1	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa)
	Dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
	Hey2	Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
	Rita1	RBPJ-interacting and tubulin-associated protein. (258 aa)
	I79_018902	Arrestin domain-containing protein 1. (459 aa)
	Nfkbia	NF-kappa-B inhibitor alpha. (224 aa)
	Dlk1	Protein delta-like 1. (361 aa)
	Gpsm3	Neurogenic locus notch-like protein 4. (1797 aa)
	Hif1an	Hypoxia-inducible factor 1-alpha inhibitor. (312 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arrb1	I79_008639	G3IIY3	G3HDQ3	Beta-arrestin-1.	NF-kappa-B inhibitor alpha.	0.470
Arrb1	I79_008640	G3IIY3	G3HDQ4	Beta-arrestin-1.	NF-kappa-B inhibitor alpha.	0.470
Arrb1	Nfkbia	G3IIY3	G3I3X5	Beta-arrestin-1.	NF-kappa-B inhibitor alpha.	0.470
Bmp7	Dlx2	G3HBL1	G3GUB7	Bone morphogenetic protein 7.	Homeobox protein DLX-2.	0.536
Cbfa2t2	I79_010588	G3HAM3	G3HIW0	Protein CBFA2T2.	Cyclin-C.	0.564
Cdk3	I79_010588	G3HTW4	G3HIW0	Cell division protein kinase 3; Belongs to the protein kinase superfamily.	Cyclin-C.	0.846
Dll1	Dll4	G3HNT7	G3ICK3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.942
Dll1	Gpsm3	G3HNT7	G3HZC0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch-like protein 4.	0.767
Dll1	Hey2	G3HNT7	G3IB43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.540
Dll1	I79_015033	G3HNT7	G3HVP3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.560
Dll1	Lfng	G3HNT7	G3GVF0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.714
Dll1	Rfng	G3HNT7	G3GXD4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase radical fringe.	0.652
Dll4	Dll1	G3ICK3	G3HNT7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.942
Dll4	Gpsm3	G3ICK3	G3HZC0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Neurogenic locus notch-like protein 4.	0.803
Dll4	Hey2	G3ICK3	G3IB43	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 2.	0.712
Dll4	I79_015033	G3ICK3	G3HVP3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.535
Dll4	Lfng	G3ICK3	G3GVF0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase.	0.543
Dll4	Rfng	G3ICK3	G3GXD4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Beta-1,3-N-acetylglucosaminyltransferase radical fringe.	0.517
Dlx1	Dlx2	G3GUB6	G3GUB7	Homeobox protein DLX-1.	Homeobox protein DLX-2.	0.841
Dlx2	Bmp7	G3GUB7	G3HBL1	Homeobox protein DLX-2.	Bone morphogenetic protein 7.	0.536