STRINGSTRING
I79_008173 I79_008173 I79_007699 I79_007699 I79_007629 I79_007629 I79_007399 I79_007399 Sirt1 Sirt1 Atp1a1 Atp1a1 Pip4k2b Pip4k2b Dbi Dbi Insig2 Insig2 I79_005506 I79_005506 I79_005488 I79_005488 I79_025689 I79_025689 Ormdl3 Ormdl3 Sorl1 Sorl1 Nfkb1 Nfkb1 I79_025482 I79_025482 Crtc3 Crtc3 I79_024089 I79_024089 Abca2 Abca2 I79_023937 I79_023937 Bscl2 Bscl2 I79_023498 I79_023498 I79_023496 I79_023496 I79_023247 I79_023247 Ormdl1 Ormdl1 H671_3g10030 H671_3g10030 Hcar1 Hcar1 Hcar2 Hcar2 I79_020433 I79_020433 Sik1 Sik1 H671_5g14804 H671_5g14804 Ppp2r5a Ppp2r5a Trib3 Trib3 Rest Rest I79_019878 I79_019878 Apoc3 Apoc3 Adra2a Adra2a Fgf19 Fgf19 Pdgfb Pdgfb Serpina12 Serpina12 Asxl3 Asxl3 Pik3ip1 Pik3ip1 I79_004628 I79_004628 Erlin2 Erlin2 Acadvl Acadvl Hrh1 Hrh1 Ccdc3 Ccdc3 I79_001744 I79_001744 Ncor1 Ncor1 Prox1 Prox1 Akt1 Akt1 Adora1 Adora1 Slc27a1 Slc27a1 SIRT4 SIRT4 I79_000973 I79_000973 I79_000677 I79_000677 I79_000120 I79_000120 IL1B IL1B Dkkl1 Dkkl1 I79_016547 I79_016547 Tnf Tnf Washc1 Washc1 Wdtc1 Wdtc1 I79_015832 I79_015832 I79_015806 I79_015806 Nr0b1 Nr0b1 Dab2ip Dab2ip Dkk3 Dkk3 I79_015207 I79_015207 Pip4k2c Pip4k2c I79_014954 I79_014954 Dgat2 Dgat2 Gper1 Gper1 Apoa2 Apoa2 Sphk1 Sphk1 CgPICR_002342 CgPICR_002342 I79_013773 I79_013773 Ormdl2 Ormdl2 Snai2 Snai2 Fmo2 Fmo2 Fmo4 Fmo4 I79_012733 I79_012733 I79_012722 I79_012722 Etfbkmt Etfbkmt Apoc2 Apoc2 Apoe Apoe Mfsd2a Mfsd2a Brca1 Brca1 I79_010588 I79_010588 Wnt4 Wnt4 I79_010352 I79_010352 Prkaa1 Prkaa1 Snai1 Snai1 I79_008906 I79_008906 I79_008810 I79_008810 Gpld1 Gpld1 Cyp7a1 Cyp7a1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_008173Perilipin; Belongs to the perilipin family. (419 aa)
I79_007699GTPase IMAP family member 5. (344 aa)
I79_007629Lipin-1. (895 aa)
I79_007399MAM and LDL-receptor class A domain-containing protein C10orf112. (1182 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
Atp1a1Sodium/potassium-transporting ATPase subunit alpha. (773 aa)
Pip4k2bPhosphatidylinositol-5-phosphate 4-kinase type-2 beta. (375 aa)
DbiAcyl-CoA-binding protein. (119 aa)
Insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
I79_005506Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha. (320 aa)
I79_005488Progesterone-induced-blocking factor 1. (757 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
Ormdl3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
Sorl1Sortilin-related receptor. (223 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
Crtc3CREB-regulated transcription coactivator 3. (175 aa)
I79_024089Lysophosphatidylcholine acyltransferase 1. (192 aa)
Abca2ATP-binding cassette sub-family A member 2. (457 aa)
I79_023937Sortilin-related receptor. (88 aa)
Bscl2Leucine-rich repeat neuronal protein 4. (224 aa)
I79_023498Seipin. (163 aa)
I79_023496Seipin. (71 aa)
I79_023247CREB-regulated transcription coactivator 3. (113 aa)
Ormdl1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
H671_3g10030Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (204 aa)
Hcar1G-protein coupled receptor 81; Belongs to the G-protein coupled receptor 1 family. (343 aa)
Hcar2Hydroxycarboxylic acid receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
I79_020433Carcinoembryonic antigen-related cell adhesion molecule 1. (155 aa)
Sik1Serine/threonine-protein kinase SIK1. (729 aa)
H671_5g14804Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1012 aa)
Ppp2r5aSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform. (83 aa)
Trib3Tribbles-like 3. (353 aa)
RestRE1-silencing transcription factor. (1047 aa)
I79_019878Sortilin. (1038 aa)
Apoc3Apolipoprotein C-III. (76 aa)
Adra2aAlpha-2A adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Serpina12Serpin A12; Belongs to the serpin family. (414 aa)
Asxl3Putative Polycomb group protein ASXL3. (1735 aa)
Pik3ip1Phosphoinositide-3-kinase-interacting protein 1. (51 aa)
I79_004628Phosphodiesterase. (786 aa)
Erlin2Erlin-2. (339 aa)
AcadvlVery long-chain specific acyl-CoA dehydrogenase, mitochondrial. (652 aa)
Hrh1Histamine H1 receptor; Belongs to the G-protein coupled receptor 1 family. (489 aa)
Ccdc3Coiled-coil domain-containing protein 3. (272 aa)
I79_001744Nuclear receptor corepressor 1. (680 aa)
Ncor1Nuclear receptor corepressor 1. (1591 aa)
Prox1Prospero homeobox protein 1. (738 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
Slc27a1Long-chain fatty acid transport protein 1. (218 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (255 aa)
I79_000973Transcription factor SOX-10. (360 aa)
I79_000677Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Dkkl1Dickkopf-like protein 1. (230 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
Washc1WAS protein family-like 1. (497 aa)
Wdtc1WD and tetratricopeptide repeats protein 1. (675 aa)
I79_015832ORM1-like protein 1. (113 aa)
I79_015806Acyl-CoA-binding protein. (87 aa)
Nr0b1Nuclear receptor subfamily 0 group B member 1. (470 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
Dkk3Dickkopf-related protein 3. (348 aa)
I79_01520725-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (232 aa)
Pip4k2cPhosphatidylinositol-5-phosphate 4-kinase type-2 gamma. (363 aa)
I79_014954Autophagy-related protein 7. (439 aa)
Dgat2Diacylglycerol O-acyltransferase 2. (388 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Apoa2Apolipoprotein A-II-like protein. (101 aa)
Sphk1Sphingosine kinase 1. (383 aa)
CgPICR_002342Acyl-CoA-binding protein. (87 aa)
I79_013773cGMP-inhibited 3',5'-cyclic phosphodiesterase B. (265 aa)
Ormdl2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
Snai2Zinc finger protein SNAI2-like protein. (268 aa)
Fmo2Flavin-containing monooxygenase. (129 aa)
Fmo4Flavin-containing monooxygenase. (367 aa)
I79_012733Flavin-containing monooxygenase. (88 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
EtfbkmtUPF0516 protein C12orf72-like. (126 aa)
Apoc2Apolipoprotein C-II. (100 aa)
ApoeApolipoprotein E. (313 aa)
Mfsd2aMajor facilitator superfamily domain-containing protein 2. (527 aa)
Brca1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1790 aa)
I79_010588Cyclin-C. (246 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_010352Acetyl-CoA carboxylase 2. (2287 aa)
Prkaa1Non-specific serine/threonine protein kinase. (477 aa)
Snai1Zinc finger protein SNAI1-like protein. (264 aa)
I79_008906Zinc finger protein Gfi-1. (333 aa)
I79_008810Protein arginine N-methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (495 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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