STRINGSTRING
Sphk1 Sphk1 Cdt1 Cdt1 Edn3 Edn3 Anapc11 Anapc11 Cd28 Cd28 I79_003329 I79_003329 I79_003549 I79_003549 Edn1 Edn1 Nusap1 Nusap1 Anapc7 Anapc7 Camkk2 Camkk2 I79_005228 I79_005228 Igf1 Igf1 I79_007063 I79_007063 I79_008560 I79_008560 Gfra3 Gfra3 Cdc27 Cdc27 Rgcc Rgcc Igf1r Igf1r I79_011333 I79_011333 Rb1 Rb1 I79_013660 I79_013660 Pdgfrb Pdgfrb I79_014177 I79_014177 Insr Insr Npm3 Npm3 I79_015916 I79_015916 Tnf Tnf IL1B IL1B Pdgfb Pdgfb Lrp5 Lrp5 Tgfa Tgfa I79_019149 I79_019149 Nup62 Nup62 Sh2b1 Sh2b1 I79_019517 I79_019517 I79_019666 I79_019666 Prap1 Prap1 I79_021125 I79_021125 Ereg Ereg Cul3 Cul3 I79_021564 I79_021564 I79_023638 I79_023638 Dmrt1 Dmrt1 Mad2l1bp Mad2l1bp Smpd3 Smpd3 I79_026101 I79_026101
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sphk1Sphingosine kinase 1. (383 aa)
Cdt1DNA replication factor Cdt1. (553 aa)
Edn3Endothelin-3. (274 aa)
Anapc11Anaphase-promoting complex subunit 11. (88 aa)
Cd28T-cell-specific surface glycoprotein CD28. (100 aa)
I79_003329Cell division cycle protein 16-like. (453 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Edn1Endothelin-1. (202 aa)
Nusap1Nucleolar and spindle-associated protein 1. (448 aa)
Anapc7Anaphase-promoting complex subunit 7. (565 aa)
Camkk2Anaphase-promoting complex subunit 5. (1188 aa)
I79_005228MAD2L1-binding protein. (148 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_007063Hepatocyte growth factor receptor. (1222 aa)
I79_008560Cell division cycle protein 27-like. (182 aa)
Gfra3Cell division cycle protein 23-like. (668 aa)
Cdc27Cell division cycle protein 27-like. (316 aa)
RgccResponse gene to complement 32 protein. (153 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
I79_011333Sphingomyelin phosphodiesterase 3. (410 aa)
Rb1Retinoblastoma-associated protein. (302 aa)
I79_013660Beta-type platelet-derived growth factor receptor. (454 aa)
PdgfrbBeta-type platelet-derived growth factor receptor. (528 aa)
I79_014177PH-interacting protein. (1039 aa)
InsrInsulin receptor. (114 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
I79_015916Insulin-like growth factor II. (155 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
TgfaProtransforming growth factor alpha. (211 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Nup62Nuclear pore glycoprotein p62. (521 aa)
Sh2b1SH2B adapter protein 1. (443 aa)
I79_019517SH2B adapter protein 1. (226 aa)
I79_019666Tetratricopeptide repeat protein 6. (694 aa)
Prap1Proline-rich acidic protein 1. (148 aa)
I79_021125Epigen. (135 aa)
EregProepiregulin. (162 aa)
Cul3Cullin-3; Belongs to the cullin family. (746 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
I79_023638Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2379 aa)
Dmrt1Doublesex-and mab-3-related transcription factor 1. (158 aa)
Mad2l1bpMAD2L1-binding protein. (276 aa)
Smpd3Sphingomyelin phosphodiesterase 3. (446 aa)
I79_026101E3 SUMO-protein ligase NSE2. (68 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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