STRINGSTRING
Nos1 Nos1 Mmp2 Mmp2 I79_006005 I79_006005 Ahr Ahr Adm Adm CgPICR_019210 CgPICR_019210 Cx3cl1 Cx3cl1 I79_020258 I79_020258 Dusp5 Dusp5 I79_001488 I79_001488 Dock5 Dock5 Bmpr2 Bmpr2 Lep Lep Hif1a Hif1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
Mmp272 kDa type IV collagenase. (662 aa)
I79_006005Melatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (240 aa)
AhrAryl hydrocarbon receptor. (247 aa)
AdmProcalcitonin/adrenomedullin containing protein. (184 aa)
CgPICR_019210Melatonin receptor type 1B. (112 aa)
Cx3cl1Fractalkine. (335 aa)
I79_020258Dedicator of cytokinesis protein 4; Belongs to the DOCK family. (1853 aa)
Dusp5Dual specificity protein phosphatase 5. (110 aa)
I79_001488Rho GTPase-activating protein 10-like. (439 aa)
Dock5Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (1446 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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