STRINGSTRING
Anxa1 Anxa1 Lpgat1 Lpgat1 Nr1h2 Nr1h2 I79_007247 I79_007247 CgPICR_005982 CgPICR_005982 Apoa5 Apoa5 Irs1 Irs1 I79_022367 I79_022367 I79_022390 I79_022390 Ppara Ppara Abcd2 Abcd2 Irs2 Irs2 Cpt1a Cpt1a I79_025689 I79_025689 Avpr1a Avpr1a Ghsr Ghsr Rgn Rgn Nr1h3 Nr1h3 Agt Agt Ptgs2 Ptgs2 Pla2g4a Pla2g4a Mid1ip1 Mid1ip1 Mlycd Mlycd I79_008173 I79_008173 C1qtnf2 C1qtnf2 Fabp1 Fabp1 Akt2 Akt2 Mapk9 Mapk9 Apoc2 Apoc2 I79_013437 I79_013437 Ppard Ppard Cd74 Cd74 I79_013971 I79_013971 PPARG PPARG Dgat1 Dgat1 Ppargc1a Ppargc1a Adipoq Adipoq Hnf4a Hnf4a IL1B IL1B Pla2g3 Pla2g3 I79_018654 I79_018654 ELOVL5 ELOVL5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Anxa1Annexin. (346 aa)
Lpgat1Acyl-CoA:lysophosphatidylglycerol acyltransferase 1. (351 aa)
Nr1h2Oxysterols receptor LXR-beta. (445 aa)
I79_007247Williams-Beuren syndrome chromosomal region 14 protein-like. (709 aa)
CgPICR_005982Apolipoprotein A-IV. (230 aa)
Apoa5Apolipoprotein A-V. (363 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_022367Nucleobindin-2. (420 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
Abcd2ATP-binding cassette sub-family D member 2. (741 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
Avpr1aVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
RgnRegucalcin. (265 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Pla2g4aPhospholipase A2. (749 aa)
Mid1ip1Mid1-interacting protein 1. (183 aa)
MlycdMalonyl-CoA decarboxylase, mitochondrial. (190 aa)
I79_008173Perilipin; Belongs to the perilipin family. (419 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
Fabp1Fatty acid-binding protein, liver. (149 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
Mapk9Mitogen-activated protein kinase 9. (303 aa)
Apoc2Apolipoprotein C-II. (100 aa)
I79_013437Nuclear receptor subfamily 4 group A member 3. (598 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
Cd74H-2 class II histocompatibility antigen gamma chain. (329 aa)
I79_013971ATP-binding cassette sub-family D member 1. (694 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Dgat1Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (327 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
AdipoqAdiponectin. (248 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Pla2g3Group 3 secretory phospholipase A2. (398 aa)
I79_018654Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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