STRINGSTRING
I79_025745 I79_025745 Star Star I79_010155 I79_010155 I79_010458 I79_010458 Wnt4 Wnt4 I79_021093 I79_021093 I79_019630 I79_019630 I79_019629 I79_019629 Cga Cga I79_009834 I79_009834 Fgf1 Fgf1 Scp2 Scp2 Bmp6 Bmp6 Cyp7a1 Cyp7a1 I79_007989 I79_007989 I79_007261 I79_007261 I79_019626 I79_019626 FSHB FSHB Igf1r Igf1r I79_019625 I79_019625 Apoa5 Apoa5 CgPICR_005982 CgPICR_005982 Apoa1 Apoa1 Igf1 Igf1 Nr1d1 Nr1d1 I79_018763 I79_018763 I79_018762 I79_018762 I79_018761 I79_018761 Tnf Tnf I79_015916 I79_015916 Ppargc1a Ppargc1a Apoe Apoe Abcg1 Abcg1 Scap Scap
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
StarSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (279 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
I79_010458Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (451 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
I79_021093Sterol regulatory element-binding protein 2. (2034 aa)
I79_019630Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family. (765 aa)
I79_019629Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)
CgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (160 aa)
I79_009834Disabled-like 2. (705 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Scp2Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (360 aa)
I79_007989Farnesyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. (375 aa)
I79_007261NADPH--cytochrome P450 reductase. (522 aa)
I79_019626Liver carboxylesterase 4. (105 aa)
FSHBFollicle stimulating hormone beta-subunit protein. (129 aa)
Igf1rInsulin-like growth factor 1 receptor. (191 aa)
I79_019625Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (514 aa)
Apoa5Apolipoprotein A-V. (363 aa)
CgPICR_005982Apolipoprotein A-IV. (230 aa)
Apoa1Apolipoprotein A-I. (264 aa)
Igf1Insulin-like growth factor I. (75 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
I79_018763Liver carboxylesterase 4. (393 aa)
I79_018762Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (370 aa)
I79_018761Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (448 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_015916Insulin-like growth factor II. (155 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
ApoeApolipoprotein E. (313 aa)
Abcg1ATP-binding cassette sub-family G member 1. (647 aa)
ScapSterol regulatory element-binding protein cleavage-activating protein. (1276 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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