STRINGSTRING
I79_005344 I79_005344 IMPDH IMPDH I79_002522 I79_002522 Nme7 Nme7 GNAI3 GNAI3 IMPDH2 IMPDH2 I79_024397 I79_024397 H671_2g5922 H671_2g5922 I79_023016 I79_023016 Efl1 Efl1 I79_021837 I79_021837 I79_006155 I79_006155 I79_021836 I79_021836 I79_021835 I79_021835 Entpd7 Entpd7 Rhoq Rhoq Gimap4 Gimap4 CgPICR_019818 CgPICR_019818 H671_7g18194 H671_7g18194 CgPICR_020542 CgPICR_020542 Nme3 Nme3 I79_007877 I79_007877 I79_009122 I79_009122 Nme6 Nme6 CgPICR_014495 CgPICR_014495 AK3 AK3 Opa1 Opa1 Ampd2 Ampd2 I79_018438 I79_018438 Gtpbp1 Gtpbp1 I79_017181 I79_017181 Rab23 Rab23 Ak4 Ak4 Ampd3 Ampd3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_005344Adenylate kinase isoenzyme 4, mitochondrial. (106 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (437 aa)
I79_002522GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (227 aa)
Nme7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (160 aa)
GNAI3Guanine nucleotide binding protein alpha inhibiting 3. (354 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase 2; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. Belongs to the IMPDH/GMPR family. (514 aa)
I79_024397GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (128 aa)
H671_2g5922GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
I79_023016Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (250 aa)
Efl1Elongation factor Tu GTP-binding domain-containing protein 1. (759 aa)
I79_021837Leucine-rich repeat serine/threonine-protein kinase 2. (441 aa)
I79_006155Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (146 aa)
I79_021836Leucine-rich repeat serine/threonine-protein kinase 2. (1184 aa)
I79_021835Leucine-rich repeat serine/threonine-protein kinase 2. (354 aa)
Entpd7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (558 aa)
RhoqRho-related GTP-binding protein RhoQ. (126 aa)
Gimap4GTPase IMAP family member 4. (189 aa)
CgPICR_019818GTPase IMAP family member 7. (291 aa)
H671_7g18194Nucleoside diphosphate kinase. (152 aa)
CgPICR_020542Nucleoside diphosphate kinase. (152 aa)
Nme3Nucleoside diphosphate kinase. (169 aa)
I79_007877Nucleoside diphosphate kinase. (228 aa)
I79_009122Thioredoxin domain-containing protein 6. (237 aa)
Nme6Nucleoside diphosphate kinase. (186 aa)
CgPICR_014495GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa)
Opa1Dynamin-like 120 kDa protein, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
Ampd2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (798 aa)
I79_018438Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (202 aa)
Gtpbp1GTP-binding protein 1. (311 aa)
I79_017181Zinc finger protein 639; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (787 aa)
Rab23Ras-related protein Rab-23. (236 aa)
Ak4Adenylate kinase isoenzyme 4, mitochondrial; Belongs to the adenylate kinase family. (161 aa)
Ampd3AMP deaminase 3. (102 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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