STRINGSTRING
I79_022367 I79_022367 Irs1 Irs1 I79_018654 I79_018654 Ppargc1a Ppargc1a Dgat1 Dgat1 PPARG PPARG I79_013971 I79_013971 Ppard Ppard Mlycd Mlycd I79_008173 I79_008173 C1qtnf2 C1qtnf2 Fabp1 Fabp1 Akt2 Akt2 I79_013437 I79_013437 I79_025689 I79_025689 Irs2 Irs2 Cpt1a Cpt1a Abcd2 Abcd2 Ppara Ppara I79_022390 I79_022390
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_022367Nucleobindin-2. (420 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_018654Carnitine O-palmitoyltransferase 1, liver isoform. (467 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Dgat1Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family. (327 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_013971ATP-binding cassette sub-family D member 1. (694 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
MlycdMalonyl-CoA decarboxylase, mitochondrial. (190 aa)
I79_008173Perilipin; Belongs to the perilipin family. (419 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
Fabp1Fatty acid-binding protein, liver. (149 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
I79_013437Nuclear receptor subfamily 4 group A member 3. (598 aa)
I79_025689Epididymal-specific lipocalin-13; Belongs to the calycin superfamily. Lipocalin family. (158 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform. (127 aa)
Abcd2ATP-binding cassette sub-family D member 2. (741 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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