STRINGSTRING
I79_002157 I79_002157 Klf15 Klf15 Ostn Ostn Appl1 Appl1 Prkcd Prkcd Ahi1 Ahi1 Aspscr1 Aspscr1 Slc1a2 Slc1a2 Lep Lep Nfe2l2 Nfe2l2 I79_004244 I79_004244 Akt1 Akt1 C2cd5 C2cd5 Capn10 Capn10 I79_005331 I79_005331 Mef2a Mef2a Igf1 Igf1 I79_006467 I79_006467 I79_006468 I79_006468 I79_006469 I79_006469 Pea15 Pea15 Adipor2 Adipor2 I79_007089 I79_007089 I79_007090 I79_007090 Crebl2 Crebl2 C1qtnf2 C1qtnf2 Rnasel Rnasel I79_009691 I79_009691 I79_009708 I79_009708 Prkci Prkci Rps6kb1 Rps6kb1 Akt2 Akt2 I79_012659 I79_012659 I79_012764 I79_012764 Ikzf4 Ikzf4 Ocln Ocln I79_013817 I79_013817 I79_014015 I79_014015 I79_014369 I79_014369 I79_014372 I79_014372 Insr Insr Oga Oga I79_015895 I79_015895 Adipoq Adipoq Tnf Tnf I79_016547 I79_016547 Mapk14 Mapk14 Fgf21 Fgf21 Pth Pth Gsk3a Gsk3a Erfe Erfe C1qtnf12 C1qtnf12 I79_018194 I79_018194 Fgf19 Fgf19 Rhoq Rhoq Tert Tert Myc Myc I79_025454 I79_025454 Pid1 Pid1 I79_024415 I79_024415 Irs2 Irs2 Stxbp3 Stxbp3 Mfn2 Mfn2 Hk2 Hk2 Irs1 Irs1 Rap1a Rap1a Enpp1 Enpp1 I79_020506 I79_020506
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_002157Phosphotransferase. (266 aa)
Klf15Krueppel-like factor 15. (414 aa)
OstnOsteocrin. (105 aa)
Appl1DCC-interacting protein 13-alpha. (664 aa)
PrkcdNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (437 aa)
Ahi1Jouberin. (988 aa)
Aspscr1Tether containing UBX domain for GLUT4. (473 aa)
Slc1a2Amino acid transporter. (553 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
Nfe2l2Nuclear factor erythroid 2-related factor 2. (588 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
C2cd5Uncharacterized protein KIAA0528. (800 aa)
Capn10Calpain-10; Belongs to the peptidase C2 family. (722 aa)
I79_005331Receptor tyrosine-protein kinase erbB-4. (480 aa)
Mef2aMyocyte-specific enhancer factor 2A. (496 aa)
Igf1Insulin-like growth factor I. (75 aa)
I79_006467Intelectin-1a. (290 aa)
I79_006468Intelectin-1a. (333 aa)
I79_006469Intelectin-1a. (315 aa)
Pea15Astrocytic phosphoprotein PEA-15. (130 aa)
Adipor2Adiponectin receptor protein 2. (386 aa)
I79_007089Receptor tyrosine-protein kinase erbB-4. (225 aa)
I79_007090Receptor tyrosine-protein kinase erbB-4. (182 aa)
Crebl2cAMP-responsive element-binding protein-like 2. (79 aa)
C1qtnf2Complement C1q tumor necrosis factor-related protein 2. (285 aa)
Rnasel2-5A-dependent ribonuclease. (525 aa)
I79_009691Growth factor receptor-bound protein 10. (518 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
Rps6kb1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
Akt2Non-specific serine/threonine protein kinase. (200 aa)
I79_012659Reticulon. (347 aa)
I79_012764Ras GTPase-activating protein 1. (826 aa)
Ikzf4Receptor protein-tyrosine kinase. (1902 aa)
OclnOccludin. (488 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
I79_014015Oxysterol-binding protein; Belongs to the OSBP family. (472 aa)
I79_014369Intelectin-1a. (279 aa)
I79_014372Intelectin-1a. (626 aa)
InsrInsulin receptor. (114 aa)
OgaBifunctional protein NCOAT. (842 aa)
I79_015895Sorbin and SH3 domain-containing protein 1. (852 aa)
AdipoqAdiponectin. (248 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
I79_016547DCC-interacting protein 13-beta. (634 aa)
Mapk14Mitogen-activated protein kinase. (349 aa)
Fgf21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Gsk3aGlycogen synthase kinase-3 alpha. (653 aa)
ErfeProtein FAM132B. (344 aa)
C1qtnf12Protein FAM132A. (61 aa)
I79_018194Protein FAM132A. (127 aa)
Fgf19Fibroblast growth factor 15; Belongs to the heparin-binding growth factors family. (115 aa)
RhoqRho-related GTP-binding protein RhoQ. (126 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
Pid1PTB-containing, cubilin and LRP1-interacting protein. (159 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
Irs2Insulin receptor substrate 2. (465 aa)
Stxbp3Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
Mfn2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
Hk2Hexokinase-2. (704 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
Rap1aRas-related protein Rap-1A. (184 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_020506POU domain, class 4, transcription factor 2. (207 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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