STRINGSTRING
Phb Phb I79_011003 I79_011003 I79_010863 I79_010863 Arid5b Arid5b Wnt4 Wnt4 Kitlg Kitlg Sfrp1 Sfrp1 Adrm1 Adrm1 Eif2b2 Eif2b2 I79_009416 I79_009416 Bcl2l1 Bcl2l1 Fst Fst I79_008250 I79_008250 I79_007693 I79_007693 I79_007548 I79_007548 Ncoa6 Ncoa6 Sirt1 Sirt1 I79_007297 I79_007297 Serpine1 Serpine1 I79_006881 I79_006881 I79_006254 I79_006254 I79_006036 I79_006036 FSHR FSHR LHCGR LHCGR I79_005358 I79_005358 Nrip1 Nrip1 Lhfpl2 Lhfpl2 I79_004452 I79_004452 Tiparp Tiparp Ptx3 Ptx3 Ccdc182 Ccdc182 Mmp2 Mmp2 Scaper Scaper Acsbg1 Acsbg1 I79_003312 I79_003312 Csmd1 Csmd1 Lep Lep I79_002785 I79_002785 Nup107 Nup107 Src Src Eif2b4 Eif2b4 Foxo3 Foxo3 Agt Agt Pla2g4a Pla2g4a Taf4 Taf4 I79_001957 I79_001957 I79_001955 I79_001955 Lhx8 Lhx8 I79_001842 I79_001842 Lfng Lfng I79_001487 I79_001487 Znf830 Znf830 Fanca Fanca I79_011183 I79_011183 Casp2 Casp2 I79_011448 I79_011448 I79_011711 I79_011711 I79_011712 I79_011712 Lhx9 Lhx9 I79_011834 I79_011834 Brca2 Brca2 Fancf Fancf H671_3g8701 H671_3g8701 I79_012512 I79_012512 I79_012799 I79_012799 Pcyt1b Pcyt1b I79_012951 I79_012951 Bmp15 Bmp15 I79_013395 I79_013395 I79_013438 I79_013438 Mmp19 Mmp19 Ahr Ahr Smad4 Smad4 Idh1 Idh1 I79_014552 I79_014552 Amhr2 Amhr2 I79_014818 I79_014818 Inhba Inhba I79_014940 I79_014940 Gpr149 Gpr149 Lhb Lhb I79_016800 I79_016800 I79_016810 I79_016810 Eif2b5 Eif2b5 I79_017826 I79_017826 Adamts1 Adamts1 I79_018485 I79_018485 Adcyap1 Adcyap1 H671_1g2978 H671_1g2978 FSHB FSHB Myc Myc I79_025441 I79_025441 I79_025221 I79_025221 Kit Kit I79_025170 I79_025170 I79_024593 I79_024593 I79_024481 I79_024481 Pdgfra Pdgfra Arrb1 Arrb1 Pitx2 Pitx2 Fzd4 Fzd4 I79_022080 I79_022080 I79_022034 I79_022034 Tnfaip6 Tnfaip6 I79_021624 I79_021624 I79_021283 I79_021283 Ereg Ereg Fgf7 Fgf7 Inha Inha I79_019506 I79_019506 Ube3a Ube3a Nr5a1 Nr5a1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PhbProhibitin. (272 aa)
I79_011003Doublesex-and mab-3-related transcription factor A1. (313 aa)
I79_010863Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (533 aa)
Arid5bAT-rich interactive domain-containing protein 5B. (945 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
KitlgKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
Adrm1Proteasomal ubiquitin receptor ADRM1. (407 aa)
Eif2b2Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (257 aa)
I79_009416Serine-protein kinase ATM. (1640 aa)
Bcl2l1Bcl-2-like protein 1. (233 aa)
FstFollistatin. (316 aa)
I79_008250Endothelin-2. (137 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
I79_007548Angiopoietin-1. (112 aa)
Ncoa6Nuclear receptor coactivator 6. (1843 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
I79_006881CUB and sushi domain-containing protein 2. (3527 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006036Sphingosine-1-phosphate lyase 1. (568 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (487 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (688 aa)
I79_005358Estrogen receptor beta. (58 aa)
Nrip1Nuclear receptor-interacting protein 1. (1172 aa)
Lhfpl2Lipoma HMGIC fusion partner-like 2 protein. (209 aa)
I79_004452Prohibitin. (131 aa)
TiparpTCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
Ptx3Pentraxin-related protein PTX3. (381 aa)
Ccdc182Coiled-coil domain-containing protein ENSP00000299415-like. (153 aa)
Mmp272 kDa type IV collagenase. (662 aa)
ScaperS phase cyclin A-associated protein in the endoplasmic reticulum. (1395 aa)
Acsbg1Long-chain-fatty-acid--CoA ligase ACSBG1. (663 aa)
I79_003312CUB and sushi domain-containing protein 1. (3110 aa)
Csmd1CUB and sushi domain-containing protein 1. (106 aa)
LepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
I79_002785Beta-arrestin-2. (65 aa)
Nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (931 aa)
SrcTyrosine-protein kinase. (536 aa)
Eif2b4Translation initiation factor eIF-2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (525 aa)
Foxo3Forkhead box protein O3. (672 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Pla2g4aPhospholipase A2. (749 aa)
Taf4Transcription initiation factor TFIID subunit 4. (630 aa)
I79_001957Slit-like 3 protein. (751 aa)
I79_001955Slit-like 3 protein. (566 aa)
Lhx8LIM/homeobox protein Lhx8. (230 aa)
I79_001842MutS protein-like 4. (198 aa)
LfngBeta-1,3-N-acetylglucosaminyltransferase. (378 aa)
I79_001487Progesterone receptor. (741 aa)
Znf830Zinc finger protein 830. (369 aa)
FancaFanconi anemia group A protein-like. (1397 aa)
I79_011183Dachshund-like 1. (326 aa)
Casp2Caspase-2; Belongs to the peptidase C14A family. (421 aa)
I79_011448Homeobox protein NOBOX. (382 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
Lhx9LIM/homeobox protein Lhx9. (311 aa)
I79_011834Breast cancer type 2 susceptibility protein-like. (143 aa)
Brca2Breast cancer type 2 susceptibility protein-like. (3008 aa)
FancfFanconi anemia group F protein. (57 aa)
H671_3g8701Growth arrest-specific protein 2. (314 aa)
I79_012512Neurofilament heavy polypeptide; Belongs to the intermediate filament family. (833 aa)
I79_012799Histone-lysine N-methyltransferase MLL4. (754 aa)
Pcyt1bCholine-phosphate cytidylyltransferase B. (243 aa)
I79_012951Choline-phosphate cytidylyltransferase B. (103 aa)
Bmp15Bone morphogenetic protein 15. (369 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
I79_013438Prohibitin. (132 aa)
Mmp19Matrix metalloproteinase-19. (525 aa)
AhrAryl hydrocarbon receptor. (247 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
I79_014552Isocitrate dehydrogenase [NADP] cytoplasmic. (112 aa)
Amhr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (57 aa)
I79_014818Anti-Muellerian hormone type-2 receptor. (73 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
I79_014940Prohibitin. (85 aa)
Gpr149Putative G-protein coupled receptor 149. (541 aa)
LhbLutropin subunit beta. (81 aa)
I79_016800Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (436 aa)
I79_016810Serine-protein kinase ATM. (473 aa)
Eif2b5Translation initiation factor eIF-2B subunit epsilon. (716 aa)
I79_017826Dachshund-like 2. (125 aa)
Adamts1A disintegrin and metalloproteinase with thrombospondin motifs 1. (705 aa)
I79_018485Isocitrate dehydrogenase [NADP] cytoplasmic. (235 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide-like protein. (176 aa)
H671_1g2978Putative zinc finger protein 42 like protein. (299 aa)
FSHBFollicle stimulating hormone beta-subunit protein. (129 aa)
MycMyc proto-oncogene protein. (281 aa)
I79_025441Receptor-type tyrosine-protein phosphatase-like N. (761 aa)
I79_025221Alpha-fetoprotein. (455 aa)
KitMast/stem cell growth factor receptor. (452 aa)
I79_025170Slit-like 2 protein. (345 aa)
I79_024593Uncharacterized protein. (194 aa)
I79_024481Prohibitin. (274 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
Arrb1Beta-arrestin-1. (422 aa)
Pitx2Homeobox protein. (322 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
I79_022080Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (402 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
Tnfaip6Tumor necrosis factor-inducible gene 6 protein. (275 aa)
I79_021624Spermatogenesis-and oogenesis-specific basic helix-loop-helix-containing protein 1. (240 aa)
I79_021283Angiopoietin-1. (298 aa)
EregProepiregulin. (162 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
InhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (367 aa)
I79_019506Endoplasmic reticulum metallopeptidase 1. (676 aa)
Ube3aUbiquitin-protein ligase E3A. (873 aa)
Nr5a1Steroidogenic factor 1. (462 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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