STRINGSTRING
Mapk3 Mapk3 CgPICR_012539 CgPICR_012539 Slc30a1 Slc30a1 Daxx Daxx Hmox1 Hmox1 I79_021045 I79_021045 I79_022023 I79_022023 I79_024415 I79_024415 Kit Kit I79_025454 I79_025454 Tert Tert cytb cytb I79_010470 I79_010470 Alad Alad HAAO HAAO I79_009953 I79_009953 I79_009500 I79_009500 Fos Fos I79_008941 I79_008941 I79_008777 I79_008777 I79_008776 I79_008776 Cer1 Cer1 Cdkn1b Cdkn1b Gss Gss Mmp9 Mmp9 Pcna Pcna Akt1 Akt1 Slc34a1 Slc34a1 Sord Sord Cat Cat Ogg1 Ogg1 Nudt1 Nudt1 I79_011859 I79_011859 Atp7a Atp7a Mapk9 Mapk9 H671_21027 H671_21027 I79_012926 I79_012926 I79_014078 I79_014078 Ncf1 Ncf1 Sox2 Sox2 Gclc Gclc Cdk1 Cdk1 Sod2 Sod2 Abcb6 Abcb6 I79_015356 I79_015356 Gsn Gsn Foxa2 Foxa2 I79_016007 I79_016007 Chuk Chuk Pth Pth
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mapk3Mitogen-activated protein kinase. (408 aa)
CgPICR_012539Small ubiquitin-related modifier. (112 aa)
Slc30a1Zinc transporter 1. (284 aa)
DaxxDeath domain-associated protein 6. (708 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
I79_021045Heme oxygenase 1. (81 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
I79_024415Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (755 aa)
KitMast/stem cell growth factor receptor. (452 aa)
I79_025454Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (182 aa)
TertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (138 aa)
cytbCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
I79_010470Metallothionein-3; Belongs to the metallothionein superfamily. Type 1 family. (108 aa)
AladDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (330 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (276 aa)
I79_009953Transcription factor AP-1. (72 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
FosProto-oncogene protein c-fos. (381 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
I79_008777Metal regulatory transcription factor 1. (300 aa)
I79_008776Metal regulatory transcription factor 1. (162 aa)
Cer1Cerberus. (272 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (198 aa)
GssGlutathione synthetase. (474 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Slc34a1Sodium-dependent phosphate transport protein 2A. (629 aa)
SordSorbitol dehydrogenase. (357 aa)
CatCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (555 aa)
Ogg1N-glycosylase/DNA lyase. (335 aa)
Nudt17,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. (131 aa)
I79_011859Calcium/calmodulin-dependent protein kinase type II beta chain. (337 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
Mapk9Mitogen-activated protein kinase 9. (303 aa)
H671_21027DNA excision repair protein ERCC-1. (111 aa)
I79_012926Death domain-associated protein 6. (393 aa)
I79_014078Niemann-Pick C1 protein. (1137 aa)
Ncf1Neutrophil cytosol factor 1. (303 aa)
Sox2Transcription factor SOX-2. (273 aa)
GclcGlutamate--cysteine ligase catalytic subunit. (584 aa)
Cdk1Cell division control protein 2-like; Belongs to the protein kinase superfamily. (297 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
Abcb6ATP-binding cassette sub-family B member 6, mitochondrial. (228 aa)
I79_015356Heat shock factor protein 1. (524 aa)
GsnGelsolin. (658 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
I79_016007Cytochrome b-245 heavy chain. (396 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha. (647 aa)
PthParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (114 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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