STRINGSTRING
I79_012776 I79_012776 I79_000883 I79_000883 I79_000959 I79_000959 Lig4 Lig4 I79_001046 I79_001046 I79_001291 I79_001291 Wnt5a Wnt5a Fosl2 Fosl2 Agt Agt I79_002350 I79_002350 Brpf1 Brpf1 Uts2r Uts2r Cdk6 Cdk6 I79_002659 I79_002659 Ctc1 Ctc1 I79_003647 I79_003647 H671_3g8823 H671_3g8823 I79_005109 I79_005109 I79_005484 I79_005484 I79_005503 I79_005503 H671_xg20020 H671_xg20020 Igf1 Igf1 Fndc3b Fndc3b Mmp9 Mmp9 I79_007042 I79_007042 Wnt2 Wnt2 Serpine1 Serpine1 I79_007297 I79_007297 E2f1 E2f1 I79_007670 I79_007670 Tsc2 Tsc2 Fntb Fntb Zmpste24 Zmpste24 Ndufs4 Ndufs4 I79_008941 I79_008941 Pml Pml I79_009503 I79_009503 Itgb3 Itgb3 I79_009953 I79_009953 I79_010003 I79_010003 Fbxo4 Fbxo4 Sfrp1 Sfrp1 I79_010240 I79_010240 Tp53inp1 Tp53inp1 Aqp1 Aqp1 Ngfr Ngfr Cdkn1a Cdkn1a I79_011183 I79_011183 RPS3A RPS3A I79_011207 I79_011207 Ptprz1 Ptprz1 I79_012059 I79_012059 I79_012607 I79_012607 I79_012764 I79_012764 CgPICR_018825 CgPICR_018825 Ddr2 Ddr2 Pex2 Pex2 I79_013660 I79_013660 Pdgfrb Pdgfrb Cd74 Cd74 I79_013817 I79_013817 Tdgf1 Tdgf1 Rnaseh2b Rnaseh2b Sphk1 Sphk1 I79_014474 I79_014474 I79_014650 I79_014650 Cdc73 Cdc73 PPARG PPARG I79_015205 I79_015205 Sod2 Sod2 Parp10 Parp10 Dab2ip Dab2ip Pdgfd Pdgfd I79_016311 I79_016311 Dicer1 Dicer1 Ager Ager I79_016423 I79_016423 Lta Lta Nlrc3 Nlrc3 Lif Lif Fn1 Fn1 Ski Ski I79_017613 I79_017613 Pdgfb Pdgfb Agtr2 Agtr2 Kmt2a Kmt2a Wnt1 Wnt1 I79_019191 I79_019191 I79_019192 I79_019192 I79_019193 I79_019193 CgPICR_016639 CgPICR_016639 I79_019195 I79_019195 I79_019196 I79_019196 I79_019197 I79_019197 Med25 Med25 Gas6 Gas6 Tgfb1 Tgfb1 I79_020513 I79_020513 Emd Emd Ereg Ereg I79_021564 I79_021564 Fth1 Fth1 I79_022371 I79_022371 Anxa2 Anxa2 I79_023875 I79_023875 I79_023900 I79_023900 I79_024210 I79_024210 Pdgfra Pdgfra I79_024651 I79_024651 I79_025236 I79_025236 I79_025512 I79_025512 I79_025567 I79_025567 Myc Myc CDC6 CDC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_012776Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (143 aa)
I79_000883Ras-specific guanine nucleotide-releasing factor 1; Belongs to the peptidase C1 family. (1632 aa)
I79_000959CMRF35-like molecule 8. (295 aa)
Lig4DNA ligase. (912 aa)
I79_001046Neurofibromin. (2164 aa)
I79_001291Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (61 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Fosl2Fos-related antigen 2. (323 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
I79_002350Uncharacterized protein. (89 aa)
Brpf1Peregrin. (771 aa)
Uts2rUrotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
Cdk6Cell division protein kinase 6. (273 aa)
I79_002659High mobility group protein HMGI-C. (103 aa)
Ctc1Uncharacterized protein C17orf68-like. (1215 aa)
I79_00364740S ribosomal protein S3a. (93 aa)
H671_3g8823Beta-1,4-galactosyltransferase 7-like protein. (327 aa)
I79_005109Mpv17-like protein 2. (471 aa)
I79_005484Ferritin heavy chain; Belongs to the universal ribosomal protein uS5 family. (361 aa)
I79_005503Polycomb complex protein BMI-1. (324 aa)
H671_xg20020Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (160 aa)
Igf1Insulin-like growth factor I. (75 aa)
Fndc3bFibronectin type III domain-containing protein 3B. (1203 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
I79_00704240S ribosomal protein S3a. (95 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
E2f1Transcription factor E2F1. (367 aa)
I79_007670Histone-lysine N-methyltransferase MLL3. (1616 aa)
Tsc2Tuberin. (1546 aa)
FntbProtein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. (437 aa)
Zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
Ndufs4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (171 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
PmlPutative transcription factor PML. (540 aa)
I79_009503Uncharacterized protein. (219 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (975 aa)
I79_009953Transcription factor AP-1. (72 aa)
I79_010003Zinc finger MIZ domain-containing protein 1. (960 aa)
Fbxo4F-box only protein 4. (248 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_010240Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (111 aa)
Tp53inp1Tumor protein p53-inducible nuclear protein 1. (239 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (429 aa)
Cdkn1aCyclin-dependent kinase inhibitor 1. (163 aa)
I79_011183Dachshund-like 1. (326 aa)
RPS3A40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. (264 aa)
I79_011207DNA repair protein XRCC4. (176 aa)
Ptprz1Receptor-type tyrosine-protein phosphatase zeta. (2289 aa)
I79_012059Tripartite motif-containing protein 32. (556 aa)
I79_012607Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (568 aa)
I79_012764Ras GTPase-activating protein 1. (826 aa)
CgPICR_018825Cell division protein kinase 4. (121 aa)
Ddr2Discoidin domain-containing receptor 2. (854 aa)
Pex2Peroxisome assembly factor 1. (334 aa)
I79_013660Beta-type platelet-derived growth factor receptor. (454 aa)
PdgfrbBeta-type platelet-derived growth factor receptor. (528 aa)
Cd74H-2 class II histocompatibility antigen gamma chain. (329 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
Tdgf1Receptor-transporting protein 3. (313 aa)
Rnaseh2bRibonuclease H2 subunit B. (140 aa)
Sphk1Sphingosine kinase 1. (383 aa)
I79_014474Cyclic AMP-responsive element-binding protein 1. (325 aa)
I79_014650Parafibromin. (260 aa)
Cdc73Parafibromin. (164 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
I79_015205Cell division protein kinase 4; Belongs to the protein kinase superfamily. (367 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
Parp10Poly [ADP-ribose] polymerase. (986 aa)
Dab2ipDisabled-like 2-interacting protein. (1065 aa)
PdgfdPlatelet-derived growth factor D. (253 aa)
I79_016311PRKC apoptosis WT1 regulator protein. (214 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
AgerAdvanced glycosylation end product-specific receptor. (334 aa)
I79_016423Advanced glycosylation end product-specific receptor. (65 aa)
LtaLymphotoxin-alpha; Belongs to the tumor necrosis factor family. (202 aa)
Nlrc3Protein NLRC3. (975 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
Fn1Fibronectin. (2486 aa)
SkiSki oncogene. (636 aa)
I79_017613DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3486 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
Agtr2Type-2 angiotensin II receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
Kmt2aHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3512 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
I79_019191Phospholipase A(2). (113 aa)
I79_019192Phospholipase A(2). (103 aa)
I79_019193Phospholipase A(2). (108 aa)
CgPICR_016639Phospholipase A(2). (141 aa)
I79_019195Phospholipase A(2). (123 aa)
I79_019196Phospholipase A(2). (134 aa)
I79_019197Phospholipase A(2). (118 aa)
Med25Mediator of RNA polymerase II transcription subunit 25. (735 aa)
Gas6Growth arrest-specific protein 6. (684 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020513Homeobox protein TGIF1. (286 aa)
EmdEmerin. (186 aa)
EregProepiregulin. (162 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
Fth1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (186 aa)
I79_022371Cell division protein kinase 4. (143 aa)
Anxa2Annexin. (244 aa)
I79_023875Tripartite motif-containing protein 32. (265 aa)
I79_023900Leucine zipper putative tumor suppressor 2. (449 aa)
I79_024210Nuclear protein 1. (103 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
I79_024651Phospholipase A(2). (69 aa)
I79_02523640S ribosomal protein S3a. (65 aa)
I79_025512Urotensin-2. (88 aa)
I79_025567Phospholipase A(2). (119 aa)
MycMyc proto-oncogene protein. (281 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (561 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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