(36 nodes) Negative regulation of fibroblast proliferation network (Cricetulus griseus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	Kmt2a	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3512 aa)
	Med25	Mediator of RNA polymerase II transcription subunit 25. (735 aa)
	Emd	Emerin. (186 aa)
	Fth1	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (186 aa)
	I79_023875	Tripartite motif-containing protein 32. (265 aa)
	I79_023900	Leucine zipper putative tumor suppressor 2. (449 aa)
	Myc	Myc proto-oncogene protein. (281 aa)
	I79_024210	Nuclear protein 1. (103 aa)
	I79_000959	CMRF35-like molecule 8. (295 aa)
	I79_001046	Neurofibromin. (2164 aa)
	I79_001291	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (61 aa)
	H671_3g8823	Beta-1,4-galactosyltransferase 7-like protein. (327 aa)
	I79_005109	Mpv17-like protein 2. (471 aa)
	I79_005484	Ferritin heavy chain; Belongs to the universal ribosomal protein uS5 family. (361 aa)
	H671_xg20020	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (160 aa)
	Mmp9	Matrix metalloproteinase-9. (710 aa)
	Tsc2	Tuberin. (1546 aa)
	Fbxo4	F-box only protein 4. (248 aa)
	Sfrp1	Secreted frizzled-related protein 1. (104 aa)
	I79_010240	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (111 aa)
	Tp53inp1	Tumor protein p53-inducible nuclear protein 1. (239 aa)
	I79_011183	Dachshund-like 1. (326 aa)
	I79_012059	Tripartite motif-containing protein 32. (556 aa)
	I79_012776	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (143 aa)
	Pex2	Peroxisome assembly factor 1. (334 aa)
	I79_014650	Parafibromin. (260 aa)
	Cdc73	Parafibromin. (164 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
	Sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
	Parp10	Poly [ADP-ribose] polymerase. (986 aa)
	Dab2ip	Disabled-like 2-interacting protein. (1065 aa)
	I79_016311	PRKC apoptosis WT1 regulator protein. (214 aa)
	Lta	Lymphotoxin-alpha; Belongs to the tumor necrosis factor family. (202 aa)
	Nlrc3	Protein NLRC3. (975 aa)
	Ski	Ski oncogene. (636 aa)
	Agtr2	Type-2 angiotensin II receptor-like protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdc73	I79_014650	G3HUN9	G3HUN7	Parafibromin.	Parafibromin.	0.950
Dab2ip	I79_001046	G3HX88	G3GTQ9	Disabled-like 2-interacting protein.	Neurofibromin.	0.480
Fth1	Sod2	G3IEF1	G3HWB8	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.422
I79_001046	Dab2ip	G3GTQ9	G3HX88	Neurofibromin.	Disabled-like 2-interacting protein.	0.480
I79_001046	Tsc2	G3GTQ9	G3HBQ8	Neurofibromin.	Tuberin.	0.569
I79_014650	Cdc73	G3HUN7	G3HUN9	Parafibromin.	Parafibromin.	0.950
I79_024210	Tp53inp1	G3IK17	G3HI20	Nuclear protein 1.	Tumor protein p53-inducible nuclear protein 1.	0.757
Mmp9	PPARG	G3H8V1	G3HVG0	Matrix metalloproteinase-9.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.598
Myc	Parp10	G3IP28	G3HWJ1	Myc proto-oncogene protein.	Poly [ADP-ribose] polymerase.	0.459
PPARG	Mmp9	G3HVG0	G3H8V1	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Matrix metalloproteinase-9.	0.598
Parp10	Myc	G3HWJ1	G3IP28	Poly [ADP-ribose] polymerase.	Myc proto-oncogene protein.	0.459
Sod2	Fth1	G3HWB8	G3IEF1	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.422
Tp53inp1	I79_024210	G3HI20	G3IK17	Tumor protein p53-inducible nuclear protein 1.	Nuclear protein 1.	0.757
Tsc2	I79_001046	G3HBQ8	G3GTQ9	Tuberin.	Neurofibromin.	0.569