STRINGSTRING
Fgfr2 Fgfr2 Hlx Hlx Foxf1 Foxf1 Six2 Six2 I79_001871 I79_001871 Tcf7 Tcf7 I79_006225 I79_006225 Nipbl Nipbl I79_011789 I79_011789 Gli3 Gli3 Ihh Ihh I79_016814 I79_016814 Hnf1b Hnf1b Tcf21 Tcf21 I79_020783 I79_020783 Pitx2 Pitx2 Tcf7l2 Tcf7l2 Pdgfra Pdgfra
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
HlxH2.0-like homeobox protein. (374 aa)
Foxf1Forkhead box protein F1. (320 aa)
Six2Homeobox protein SIX2. (299 aa)
I79_001871Transcription factor Ovo-like 2. (213 aa)
Tcf7Transcription factor 7. (213 aa)
I79_006225Sonic hedgehog protein. (226 aa)
NipblNipped-B-like protein. (104 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
IhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (918 aa)
I79_016814Short stature homeobox protein 2. (194 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Tcf21Transcription factor 21. (179 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
Pitx2Homeobox protein. (322 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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