STRINGSTRING
Rbpj Rbpj Tlx1 Tlx1 Pax8 Pax8 Folr1 Folr1 Ar Ar I79_024048 I79_024048 Fgfr2 Fgfr2 I79_024314 I79_024314 Hhex Hhex Map2k1 Map2k1 Nog Nog Gli2 Gli2 Hoxa3 Hoxa3 Emp2 Emp2 Tgfbr2 Tgfbr2 Nkx3-1 Nkx3-1 Wnt5a Wnt5a I79_001239 I79_001239 Tp63 Tp63 Smarcd3 Smarcd3 Mef2c Mef2c Ext1 Ext1 Ctnnb1 Ctnnb1 I79_006693 I79_006693 Axin2 Axin2 I79_006254 I79_006254 I79_006225 I79_006225 Isl1 Isl1 I79_009500 I79_009500 CgPICR_001850 CgPICR_001850 Map2k2 Map2k2 Wnt11 Wnt11 Gli3 Gli3 Foxh1 Foxh1 Rdh10 Rdh10 Nkx3-2 Nkx3-2 I79_016797 I79_016797 I79_017126 I79_017126 Tbr1 Tbr1 Mapk3 Mapk3 I79_019198 I79_019198 I79_019199 I79_019199 Lemd2 Lemd2 I79_019286 I79_019286 I79_021155 I79_021155
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
Tlx1T-cell leukemia homeobox protein 1. (78 aa)
Pax8Paired box protein Pax-8. (452 aa)
Folr1Folate receptor alpha. (257 aa)
ArAndrogen receptor. (517 aa)
I79_024048Paired box protein Pax-3. (324 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_024314Paired box protein Pax-3. (301 aa)
HhexHematopoietically-expressed homeobox protein Hhex. (98 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
NogNoggin. (117 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
Hoxa3Homeobox protein Hox-A3. (286 aa)
Emp2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (174 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Nkx3-1Homeobox protein Nkx-3.1. (187 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
I79_001239Low-density lipoprotein receptor-related protein 2. (4664 aa)
Tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (642 aa)
Smarcd3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (300 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Ext1Exostosin-1. (388 aa)
Ctnnb1Catenin beta-1. (781 aa)
I79_006693Intraflagellar transport protein 88-like. (533 aa)
Axin2Axin-2. (809 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
I79_009500Mitogen-activated protein kinase 1. (68 aa)
CgPICR_001850Selenoprotein H. (100 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (380 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Foxh1Forkhead box protein H1. (367 aa)
Rdh10Retinol dehydrogenase 10. (65 aa)
Nkx3-2Homeobox protein Nkx-3.2. (261 aa)
I79_016797Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
I79_017126T-box brain protein 1. (74 aa)
Tbr1T-box brain protein 1. (231 aa)
Mapk3Mitogen-activated protein kinase. (408 aa)
I79_019198Putative RNA-binding protein 20. (756 aa)
I79_019199Putative RNA-binding protein 20. (349 aa)
Lemd2LEM domain-containing protein 2. (271 aa)
I79_019286Androgen receptor. (295 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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