STRINGSTRING
Ppargc1a Ppargc1a Trib1 Trib1 I79_024807 I79_024807 Ctnnbip1 Ctnnbip1 H671_1g2246 H671_1g2246 Mfn2 Mfn2 I79_021045 I79_021045 Hmox1 Hmox1 Klf4 Klf4 Ccdc142 Ccdc142 I79_019439 I79_019439 Pdcd4 Pdcd4 Sf1 Sf1 I79_018848 I79_018848 I79_018586 I79_018586 Drd4 Drd4 Efemp2 Efemp2 Aif1 Aif1 Ralbp1 Ralbp1 Adipoq Adipoq Sod2 Sod2 PPARG PPARG Gper1 Gper1 Ppard Ppard Rgs5 Rgs5 Apoe Apoe Cdkn1a Cdkn1a Il15 Il15 Npr3 Npr3 H671_xg20748 H671_xg20748 Tgfb3 Tgfb3 Comt Comt IL12B IL12B I79_008058 I79_008058 I79_007693 I79_007693 Cdkn1b Cdkn1b Il10 Il10 Mef2c Mef2c Cav1 Cav1 Gna13 Gna13 I79_006462 I79_006462 MED4 MED4 S1pr2 S1pr2 Cnn1 Cnn1 I79_005841 I79_005841 I79_005379 I79_005379 I79_005358 I79_005358 Pik3r1 Pik3r1 Igfbp5 Igfbp5 I79_003100 I79_003100 Bmpr2 Bmpr2 Tnfaip3 Tnfaip3 Gna12 Gna12 Vip Vip ilk ilk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha. (894 aa)
Trib1Tribbles-like 1. (286 aa)
I79_024807Protein FAM19A5. (87 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
H671_1g2246Protein NDRG2-like isoform 2. (328 aa)
Mfn2Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
I79_021045Heme oxygenase 1. (81 aa)
Hmox1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (290 aa)
Klf4Krueppel-like factor 4. (474 aa)
Ccdc142Coiled-coil domain-containing protein 142. (723 aa)
I79_019439Vasoactive intestinal polypeptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (303 aa)
Pdcd4Programmed cell death protein 4. (469 aa)
Sf1Splicing factor 1. (522 aa)
I79_018848Prostacyclin receptor. (229 aa)
I79_018586Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
Drd4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
Efemp2EGF-containing fibulin-like extracellular matrix protein 2. (375 aa)
Aif1Allograft inflammatory factor 1. (80 aa)
Ralbp1RalA-binding protein 1. (643 aa)
AdipoqAdiponectin. (248 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (176 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
Rgs5Regulator of G-protein signaling 5. (215 aa)
ApoeApolipoprotein E. (313 aa)
Cdkn1aCyclin-dependent kinase inhibitor 1. (163 aa)
Il15Interleukin; Belongs to the IL-15/IL-21 family. (155 aa)
Npr3Atrial natriuretic peptide clearance receptor. (387 aa)
H671_xg20748Angiotensin-converting enzyme. (644 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
ComtCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (265 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
I79_008058Guanylate cyclase. (813 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (198 aa)
Il10Interleukin-10. (178 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
Gna13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
I79_006462cGMP-dependent protein kinase 1, beta isozyme; Belongs to the protein kinase superfamily. (227 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (104 aa)
S1pr2Sphingosine 1-phosphate receptor 2. (352 aa)
Cnn1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
I79_005841Calponin-1. (79 aa)
I79_005379Tropomyosin alpha-1 chain; Belongs to the tropomyosin family. (158 aa)
I79_005358Estrogen receptor beta. (58 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (726 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
I79_003100Myocardin. (371 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
Gna12Guanine nucleotide-binding protein subunit alpha-12. (305 aa)
VipVIP peptides. (170 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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