STRINGSTRING
Npm3 Npm3 CgPICR_014751 CgPICR_014751 Mef2c Mef2c Smad2 Smad2 I79_000092 I79_000092 CgPICR_014750 CgPICR_014750 I79_019149 I79_019149 Fuz Fuz I79_019293 I79_019293 I79_019493 I79_019493 Med12 Med12 I79_022007 I79_022007 Six1 Six1 I79_022317 I79_022317 Alx3 Alx3 Tbx15 Tbx15 Prrx2 Prrx2 I79_023732 I79_023732 Fgfr2 Fgfr2 Pdgfra Pdgfra Wnt9b Wnt9b Hoxa1 Hoxa1 Hoxa2 Hoxa2 I79_009030 I79_009030 Lhx1 Lhx1 Smad3 Smad3 Tgfbr1 Tgfbr1 I79_006254 I79_006254 Nodal Nodal I79_003733 I79_003733 I79_002219 I79_002219 Tgfbr2 Tgfbr2 Six2 Six2 Tulp3 Tulp3 Dlx2 Dlx2 Mthfd1l Mthfd1l I79_009364 I79_009364 Tgfb3 Tgfb3 I79_009932 I79_009932 Nipbl Nipbl Setd2 Setd2 I79_011377 I79_011377 Runx2 Runx2 I79_011902 I79_011902 Prrx1 Prrx1 Chst11 Chst11 I79_013395 I79_013395 I79_013668 I79_013668 Eif4a3 Eif4a3 I79_014551 I79_014551 Slc39a1 Slc39a1 Ift140 Ift140 Gli3 Gli3 Rdh10 Rdh10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
CgPICR_014751Eukaryotic initiation factor 4A-III. (250 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
CgPICR_014750Eukaryotic initiation factor 4A-III. (115 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
FuzProtein fuzzy-like. (365 aa)
I79_019293Protein fuzzy-like. (60 aa)
I79_019493Mediator of RNA polymerase II transcription subunit 12. (251 aa)
Med12Mediator of RNA polymerase II transcription subunit 12. (1703 aa)
I79_022007Homeobox protein SIX4. (673 aa)
Six1Homeobox protein SIX1. (284 aa)
I79_022317WD repeat-containing protein 19. (899 aa)
Alx3Homeobox protein aristaless-like 3. (200 aa)
Tbx15T-box transcription factor TBX15. (496 aa)
Prrx2Paired mesoderm homeobox protein 2. (185 aa)
I79_023732WD repeat-containing protein 19. (196 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
Hoxa1Homeobox protein Hox-A1. (334 aa)
Hoxa2Homeobox protein Hox-A2. (76 aa)
I79_009030T-box transcription factor TBX1. (293 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
NodalNodal. (309 aa)
I79_003733Iroquois-class homeodomain protein IRX-5. (265 aa)
I79_002219Neuroendocrine secretory protein 55. (295 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Six2Homeobox protein SIX2. (299 aa)
Tulp3Tubby-like protein; Belongs to the TUB family. (414 aa)
Dlx2Homeobox protein DLX-2. (347 aa)
Mthfd1lMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (975 aa)
I79_009364Transcription factor AP-2 alpha. (411 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
I79_009932Paired mesoderm homeobox protein 2. (163 aa)
NipblNipped-B-like protein. (104 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2412 aa)
I79_011377Grainyhead-like protein 2-like. (522 aa)
Runx2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
I79_011902Paired box protein Pax-5. (386 aa)
Prrx1Paired mesoderm homeobox protein 1. (198 aa)
Chst11Carbohydrate sulfotransferase. (352 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
I79_013668Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1. (809 aa)
Eif4a3Eukaryotic initiation factor 4A-III. (279 aa)
I79_014551Matrix metalloproteinase-16. (394 aa)
Slc39a1Zinc transporter ZIP1-like protein. (324 aa)
Ift140Intraflagellar transport protein 140-like. (1462 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Rdh10Retinol dehydrogenase 10. (65 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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