STRINGSTRING
Hoxa2 Hoxa2 Runx2 Runx2 Hoxa1 Hoxa1 Slc39a1 Slc39a1 Ift140 Ift140 Bmp7 Bmp7 I79_007754 I79_007754 Mef2c Mef2c Smad2 Smad2 Lhx1 Lhx1 Ctnnb1 Ctnnb1 Wnt9b Wnt9b I79_025173 I79_025173 Pdgfra Pdgfra Fgfr2 Fgfr2 I79_023732 I79_023732 Prrx2 Prrx2 Tbx15 Tbx15 Alx3 Alx3 I79_022317 I79_022317 Six1 Six1 I79_022007 I79_022007 Col2a1 Col2a1 I79_021786 I79_021786 Dscaml1 Dscaml1 Med12 Med12 I79_019493 I79_019493 I79_019436 I79_019436 I79_019293 I79_019293 Fuz Fuz I79_019149 I79_019149 Men1 Men1 CgPICR_014750 CgPICR_014750 CgPICR_014751 CgPICR_014751 Tmem145 Tmem145 I79_016814 I79_016814 Myf5 Myf5 Flvcr1 Flvcr1 I79_016358 I79_016358 Npm3 Npm3 Rdh10 Rdh10 Alx4 Alx4 Gli3 Gli3 I79_014806 I79_014806 I79_000092 I79_000092 Mthfd1l Mthfd1l Dlx2 Dlx2 Tulp3 Tulp3 Six2 Six2 Tgfbr2 Tgfbr2 I79_002219 I79_002219 Asxl2 Asxl2 I79_003733 I79_003733 Nog Nog Hoxd4 Hoxd4 I79_005503 I79_005503 I79_005662 I79_005662 Hoxb7 Hoxb7 Hoxb6 Hoxb6 Hoxb5 Hoxb5 I79_005672 I79_005672 Hoxb2 Hoxb2 Hoxb1 Hoxb1 I79_005702 I79_005702 Nodal Nodal I79_006254 I79_006254 Tgfbr1 Tgfbr1 Smad3 Smad3 Hoxc9 Hoxc9 Hoxc4 Hoxc4 I79_014551 I79_014551 Eif4a3 Eif4a3 Alx1 Alx1 I79_013668 I79_013668 I79_013395 I79_013395 Chst11 Chst11 Prrx1 Prrx1 I79_012727 I79_012727 Zeb1 Zeb1 I79_011902 I79_011902 I79_011377 I79_011377 Setd2 Setd2 Nipbl Nipbl Hspg2 Hspg2 I79_010137 I79_010137 I79_009932 I79_009932 Tgfb3 Tgfb3 I79_009364 I79_009364 I79_009343 I79_009343 I79_009030 I79_009030 Osr1 Osr1 Hoxa11 Hoxa11 Hoxa9 Hoxa9 Hoxa7 Hoxa7 Hoxa3 Hoxa3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hoxa2Homeobox protein Hox-A2. (76 aa)
Runx2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
Hoxa1Homeobox protein Hox-A1. (334 aa)
Slc39a1Zinc transporter ZIP1-like protein. (324 aa)
Ift140Intraflagellar transport protein 140-like. (1462 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
I79_007754Homeobox protein goosecoid. (116 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
Ctnnb1Catenin beta-1. (781 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
I79_025173Down syndrome cell adhesion molecule-like protein 1. (481 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1082 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
I79_023732WD repeat-containing protein 19. (196 aa)
Prrx2Paired mesoderm homeobox protein 2. (185 aa)
Tbx15T-box transcription factor TBX15. (496 aa)
Alx3Homeobox protein aristaless-like 3. (200 aa)
I79_022317WD repeat-containing protein 19. (899 aa)
Six1Homeobox protein SIX1. (284 aa)
I79_022007Homeobox protein SIX4. (673 aa)
Col2a1Collagen alpha-1(II) chain. (709 aa)
I79_021786Collagen alpha-1(II) chain. (689 aa)
Dscaml1Down syndrome cell adhesion molecule-like protein 1. (1505 aa)
Med12Mediator of RNA polymerase II transcription subunit 12. (1703 aa)
I79_019493Mediator of RNA polymerase II transcription subunit 12. (251 aa)
I79_019436WD repeat-containing protein 60. (927 aa)
I79_019293Protein fuzzy-like. (60 aa)
FuzProtein fuzzy-like. (365 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Men1Menin. (610 aa)
CgPICR_014750Eukaryotic initiation factor 4A-III. (115 aa)
CgPICR_014751Eukaryotic initiation factor 4A-III. (250 aa)
Tmem145Multiple epidermal growth factor-like domains 8. (2639 aa)
I79_016814Short stature homeobox protein 2. (194 aa)
Myf5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
Flvcr1Feline leukemia virus subgroup C receptor-related protein 1. (222 aa)
I79_016358Feline leukemia virus subgroup C receptor-related protein 1. (100 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Rdh10Retinol dehydrogenase 10. (65 aa)
Alx4Homeobox protein aristaless-like 4. (237 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
I79_014806Homeobox protein Hox-C11. (229 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Mthfd1lMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (975 aa)
Dlx2Homeobox protein DLX-2. (347 aa)
Tulp3Tubby-like protein; Belongs to the TUB family. (414 aa)
Six2Homeobox protein SIX2. (299 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
I79_002219Neuroendocrine secretory protein 55. (295 aa)
Asxl2Putative Polycomb group protein ASXL2. (1421 aa)
I79_003733Iroquois-class homeodomain protein IRX-5. (265 aa)
NogNoggin. (117 aa)
Hoxd4Homeobox protein Hox-D10. (371 aa)
I79_005503Polycomb complex protein BMI-1. (324 aa)
I79_005662Homeobox protein Hox-B8. (156 aa)
Hoxb7Homeobox protein Hox-B7. (153 aa)
Hoxb6Homeobox protein Hox-B6. (224 aa)
Hoxb5Homeobox protein Hox-B5. (269 aa)
I79_005672Homeobox protein Hox-B3. (174 aa)
Hoxb2Homeobox protein Hox-B2. (407 aa)
Hoxb1Homeobox protein Hox-B1. (297 aa)
I79_005702Polycomb group RING finger protein 2. (398 aa)
NodalNodal. (309 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Hoxc9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
Hoxc4Homeobox protein Hox-C4. (56 aa)
I79_014551Matrix metalloproteinase-16. (394 aa)
Eif4a3Eukaryotic initiation factor 4A-III. (279 aa)
Alx1ALX homeobox protein 1. (295 aa)
I79_013668Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1. (809 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
Chst11Carbohydrate sulfotransferase. (352 aa)
Prrx1Paired mesoderm homeobox protein 1. (198 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
Zeb1Zinc finger E-box-binding homeobox 1. (1078 aa)
I79_011902Paired box protein Pax-5. (386 aa)
I79_011377Grainyhead-like protein 2-like. (522 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2412 aa)
NipblNipped-B-like protein. (104 aa)
Hspg2Basement membrane-specific heparan sulfate proteoglycan core protein. (3140 aa)
I79_010137Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (262 aa)
I79_009932Paired mesoderm homeobox protein 2. (163 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
I79_009364Transcription factor AP-2 alpha. (411 aa)
I79_009343N-myc proto-oncogene protein. (316 aa)
I79_009030T-box transcription factor TBX1. (293 aa)
Osr1Protein odd-skipped-related 1. (266 aa)
Hoxa11Homeobox protein Hox-A11. (250 aa)
Hoxa9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (271 aa)
Hoxa7Homeobox protein Hox-A7. (112 aa)
Hoxa3Homeobox protein Hox-A3. (286 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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