(80 nodes) Oligodendrocyte differentiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Sox10	Transcription factor SOX-10. (466 aa)
	Dusp10	Dual specificity protein phosphatase 10. (482 aa)
	I79_000316	Histone deacetylase 11. (301 aa)
	I79_000973	Transcription factor SOX-10. (360 aa)
	Vtn	Vitronectin. (876 aa)
	I79_001046	Neurofibromin. (2164 aa)
	Suz12	Polycomb protein Suz12. (200 aa)
	Dlx1	Homeobox protein DLX-1. (255 aa)
	Dlx2	Homeobox protein DLX-2. (347 aa)
	Cdkn2c	Cyclin-dependent kinase 4 inhibitor C. (168 aa)
	I79_002119	Wiskott-Aldrich syndrome protein family member 3. (421 aa)
	Eif2b4	Translation initiation factor eIF-2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (525 aa)
	Ckap5	Cytoskeleton-associated protein 5. (1241 aa)
	Ptprj	Receptor-type tyrosine-protein phosphatase eta. (1077 aa)
	Pax6	Paired box protein Pax-6. (544 aa)
	Slc8a3	Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
	I79_004750	Transcription factor SOX-5. (211 aa)
	Sox5	Transcription factor SOX-5. (347 aa)
	Bok	Bcl-2-related ovarian killer protein. (213 aa)
	Ascl1	Achaete-scute-like 1. (140 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	Ncstn	Nicastrin. (615 aa)
	Kcnj10	ATP-sensitive inward rectifier potassium channel 10. (379 aa)
	I79_006961	Serine/threonine-protein kinase ULK4. (1552 aa)
	I79_025798	Vitronectin. (230 aa)
	Abca2	ATP-binding cassette sub-family A member 2. (457 aa)
	Tcf7l2	Transcription factor 7-like 1. (73 aa)
	Csk	Tyrosine-protein kinase. (450 aa)
	Tppp	Tubulin polymerization-promoting protein. (236 aa)
	Bnip3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (151 aa)
	I79_022526	Myelin gene regulatory factor. (1095 aa)
	I79_022078	Homeobox protein Nkx-2.1. (190 aa)
	Trpc4	Short transient receptor potential channel 4-like protein; Belongs to the transient receptor (TC 1.A.4) family. (973 aa)
	I79_020783	Transcription factor 7-like 2. (451 aa)
	Enpp1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
	H671_xg20009	Myelin proteolipid protein. (276 aa)
	Tgfb1	Transforming growth factor beta-1. (237 aa)
	I79_019797	BDNF/NT-3 growth factors receptor. (192 aa)
	Nsun5	Putative methyltransferase NSUN5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (153 aa)
	Cntn2	Contactin-2. (1008 aa)
	Cdk5	Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	Sox8	Transcription factor SOX-8. (463 aa)
	B4galt5	Beta-1,4-galactosyltransferase 5. (344 aa)
	Eif2b2	Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (257 aa)
	Exoc4	Exocyst complex component 4. (508 aa)
	I79_009921	Exocyst complex component 4. (445 aa)
	I79_010799	Tetraspanin-2; Belongs to the tetraspanin (TM4SF) family. (155 aa)
	Fgfr3	Fibroblast growth factor receptor 3. (319 aa)
	Cntnap1	Contactin-associated protein 1. (741 aa)
	I79_011789	DNA-binding protein inhibitor ID-2. (185 aa)
	I79_011918	Transcription factor Sox-6. (395 aa)
	I79_011919	Transcription factor SOX-6. (237 aa)
	Ptprz1	Receptor-type tyrosine-protein phosphatase zeta. (2289 aa)
	Clu	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (447 aa)
	Ercc2	TFIIH basal transcription factor complex helicase subunit. (141 aa)
	I79_012652	TFIIH basal transcription factor complex helicase subunit. (108 aa)
	I79_013013	Transcription factor SOX-13. (600 aa)
	Otx2	Homeobox protein OTX2. (289 aa)
	I79_014451	Pro-neuregulin-1, membrane-bound isoform. (639 aa)
	Lpar1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	Gli3	Zinc finger protein GLI3. (1582 aa)
	Eif2b1	Translation initiation factor eIF-2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (223 aa)
	Eed	Polycomb protein EED. (262 aa)
	Neurod4	Neurogenic differentiation factor. (331 aa)
	I79_017151	Myelin-associated oligodendrocyte basic protein. (185 aa)
	Prdm8	PR domain zinc finger protein 8. (735 aa)
	Lyn	Tyrosine-protein kinase. (289 aa)
	I79_017561	Tyrosine-protein kinase Lyn. (101 aa)
	Eif2b5	Translation initiation factor eIF-2B subunit epsilon. (716 aa)
	Acy3	Aspartoacylase-2. (319 aa)
	B4galt6	Beta-1,4-galactosyltransferase 6. (235 aa)
	I79_018586	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
	I79_018913	Homeobox protein Nkx-6.2. (114 aa)
	I79_019031	Teneurin-4. (3477 aa)
	Gpr17	Uracil nucleotide/cysteinyl leukotriene receptor; Belongs to the G-protein coupled receptor 1 family. (339 aa)
	I79_019429	Contactin-1. (461 aa)
	Nlgn3	Neuroligin-3. (828 aa)
	I79_019493	Mediator of RNA polymerase II transcription subunit 12. (251 aa)
	Med12	Mediator of RNA polymerase II transcription subunit 12. (1703 aa)
	Ntrk2	Tyrosine-protein kinase receptor. (383 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ascl1	Dlx1	G3H670	G3GUB6	Achaete-scute-like 1.	Homeobox protein DLX-1.	0.501
Ascl1	Dlx2	G3H670	G3GUB7	Achaete-scute-like 1.	Homeobox protein DLX-2.	0.583
Ascl1	I79_011789	G3H670	G3HM41	Achaete-scute-like 1.	DNA-binding protein inhibitor ID-2.	0.426
B4galt5	B4galt6	G3HET2	G3I4M7	Beta-1,4-galactosyltransferase 5.	Beta-1,4-galactosyltransferase 6.	0.559
B4galt6	B4galt5	G3I4M7	G3HET2	Beta-1,4-galactosyltransferase 6.	Beta-1,4-galactosyltransferase 5.	0.559
Bnip3	Bok	G3IFW8	G3H4V6	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.	Bcl-2-related ovarian killer protein.	0.598
Bnip3	I79_018586	G3IFW8	G3I540	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	0.504
Bok	Bnip3	G3H4V6	G3IFW8	Bcl-2-related ovarian killer protein.	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.	0.598
Cdk5	Ncstn	G3HB69	G3H7X9	Cell division protein kinase 5; Belongs to the protein kinase superfamily.	Nicastrin.	0.410
Clu	I79_025798	G3HNJ3	G3IP93	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Vitronectin.	0.571
Clu	Vtn	G3HNJ3	G3GTP7	Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.	Vitronectin.	0.567
Cntn2	Cntnap1	G3HAW9	G3HLY4	Contactin-2.	Contactin-associated protein 1.	0.712
Cntn2	Ptprz1	G3HAW9	G3HMM0	Contactin-2.	Receptor-type tyrosine-protein phosphatase zeta.	0.577
Cntnap1	Cntn2	G3HLY4	G3HAW9	Contactin-associated protein 1.	Contactin-2.	0.712
Cntnap1	I79_019429	G3HLY4	G3I7E1	Contactin-associated protein 1.	Contactin-1.	0.979
Cntnap1	Ptprz1	G3HLY4	G3HMM0	Contactin-associated protein 1.	Receptor-type tyrosine-protein phosphatase zeta.	0.538
Csk	I79_014451	G3IIC0	G3HU47	Tyrosine-protein kinase.	Pro-neuregulin-1, membrane-bound isoform.	0.440
Csk	I79_017561	G3IIC0	G3I2D2	Tyrosine-protein kinase.	Tyrosine-protein kinase Lyn.	0.662
Csk	I79_018586	G3IIC0	G3I540	Tyrosine-protein kinase.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	0.529
Csk	Lyn	G3IIC0	G3I2D1	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.695