STRINGSTRING
IL1B IL1B Serpine2 Serpine2 Actr3 Actr3 I79_006225 I79_006225 Il6st Il6st Bin1 Bin1 I79_011789 I79_011789 I79_015503 I79_015503 Lif Lif I79_021945 I79_021945 Clcf1 Clcf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
Serpine2Glia-derived nexin; Belongs to the serpin family. (189 aa)
Actr3Actin-related protein 3; Belongs to the actin family. (418 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Il6stInterleukin-6 receptor subunit beta. (914 aa)
Bin1Myc box-dependent-interacting protein 1. (522 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
I79_015503Transcription factor HES-1. (92 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
I79_021945Pre-mRNA-processing factor 19. (487 aa)
Clcf1Cardiotrophin-like cytokine factor 1. (225 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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