STRINGSTRING
I79_007329 I79_007329 I79_007328 I79_007328 Ptn Ptn Ctnnb1 Ctnnb1 I79_006924 I79_006924 I79_006923 I79_006923 Hdac1 Hdac1 Dag1 Dag1 I79_006254 I79_006254 I79_006225 I79_006225 Ptpra Ptpra I79_003549 I79_003549 Cxcr4 Cxcr4 Mdk Mdk Dlx2 Dlx2 Dlx1 Dlx1 Tmem98 Tmem98 I79_001046 I79_001046 I79_000801 I79_000801 Dusp10 Dusp10 Il33 Il33 I79_018913 I79_018913 I79_019031 I79_019031 I79_020783 I79_020783 H671_1g3307 H671_1g3307 Acy3 Acy3 Dicer1 Dicer1 I79_015503 I79_015503 PPARG PPARG Tnfrsf21 Tnfrsf21 Prmt5 Prmt5 Ptprz1 Ptprz1 I79_011789 I79_011789 Mtor Mtor I79_022486 I79_022486 I79_023241 I79_023241 Tcf7l2 Tcf7l2 Tnfrsf1b Tnfrsf1b Sirt2 Sirt2 Znf365 Znf365 Hdac2 Hdac2 Dusp15 Dusp15 Rheb Rheb Il34 Il34 I79_007340 I79_007340
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_007329Histone deacetylase 1. (250 aa)
I79_007328Histone deacetylase 2. (91 aa)
PtnPleiotrophin. (168 aa)
Ctnnb1Catenin beta-1. (781 aa)
I79_006924Histone deacetylase 1. (188 aa)
I79_006923Histone deacetylase 1. (235 aa)
Hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
Dag1Dystroglycan. (893 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006225Sonic hedgehog protein. (226 aa)
PtpraReceptor-type tyrosine-protein phosphatase alpha. (1074 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
MdkMidkine. (160 aa)
Dlx2Homeobox protein DLX-2. (347 aa)
Dlx1Homeobox protein DLX-1. (255 aa)
Tmem98Transmembrane protein 98. (226 aa)
I79_001046Neurofibromin. (2164 aa)
I79_000801Histone deacetylase 1. (92 aa)
Dusp10Dual specificity protein phosphatase 10. (482 aa)
Il33Interleukin-33. (217 aa)
I79_018913Homeobox protein Nkx-6.2. (114 aa)
I79_019031Teneurin-4. (3477 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
H671_1g3307Disheveled-associated activator of morphogenesis 2. (967 aa)
Acy3Aspartoacylase-2. (319 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
I79_015503Transcription factor HES-1. (92 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Tnfrsf21Tumor necrosis factor receptor superfamily member 21. (654 aa)
Prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (577 aa)
Ptprz1Receptor-type tyrosine-protein phosphatase zeta. (2289 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
MtorSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
I79_022486GS homeobox 2. (100 aa)
I79_023241Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (558 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
Tnfrsf1bTumor necrosis factor receptor superfamily member 1B. (477 aa)
Sirt2NAD-dependent deacetylase sirtuin-2. (83 aa)
Znf365Protein ZNF365. (313 aa)
Hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
Dusp15Dual specificity protein phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (307 aa)
RhebGTP-binding protein Rheb. (179 aa)
Il34Interleukin-34. (201 aa)
I79_007340Ectonucleotide pyrophosphatase/phosphodiesterase family member 2. (592 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.