(26 nodes) Smooth muscle tissue development network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ahr	Aryl hydrocarbon receptor. (247 aa)
	Prox1	Prospero homeobox protein 1. (738 aa)
	Foxp1	Forkhead box protein P1. (696 aa)
	I79_000661	Myosin light chain kinase, smooth muscle. (1766 aa)
	I79_000973	Transcription factor SOX-10. (360 aa)
	I79_001046	Neurofibromin. (2164 aa)
	Foxp2	Forkhead box protein P2. (492 aa)
	Smo	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
	Tiparp	TCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)
	Osr1	Protein odd-skipped-related 1. (266 aa)
	I79_008965	Stimulated by retinoic acid gene 6 protein-like. (553 aa)
	Tshz3	Teashirt-like 3. (248 aa)
	I79_012894	Transcription factor AP-2 beta. (287 aa)
	I79_013660	Beta-type platelet-derived growth factor receptor. (454 aa)
	Pdgfrb	Beta-type platelet-derived growth factor receptor. (528 aa)
	Ihh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (918 aa)
	Srf	Serum response factor. (361 aa)
	Efemp2	EGF-containing fibulin-like extracellular matrix protein 2. (375 aa)
	Six1	Homeobox protein SIX1. (284 aa)
	Zfand5	AN1-type zinc finger protein 5. (213 aa)
	Ptch1	Protein patched-like 1. (1114 aa)
	I79_024483	Polycystin-2. (192 aa)
	Col3a1	Collagen alpha-1(III) chain. (1051 aa)
	I79_025625	Polycystin-2. (318 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Col3a1	Efemp2	G3IM20	G3I2G7	Collagen alpha-1(III) chain.	EGF-containing fibulin-like extracellular matrix protein 2.	0.663
Efemp2	Col3a1	G3I2G7	G3IM20	EGF-containing fibulin-like extracellular matrix protein 2.	Collagen alpha-1(III) chain.	0.663
Foxp1	Foxp2	G3GS53	G3GW16	Forkhead box protein P1.	Forkhead box protein P2.	0.575
Foxp2	Foxp1	G3GW16	G3GS53	Forkhead box protein P2.	Forkhead box protein P1.	0.575
I79_000973	I79_006225	G3GTI9	G3H796	Transcription factor SOX-10.	Sonic hedgehog protein.	0.472
I79_000973	Ihh	G3GTI9	G3HWF8	Transcription factor SOX-10.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.492
I79_001046	I79_012894	G3GTQ9	G3HQ06	Neurofibromin.	Transcription factor AP-2 beta.	0.751
I79_006225	I79_000973	G3H796	G3GTI9	Sonic hedgehog protein.	Transcription factor SOX-10.	0.472
I79_006225	I79_006254	G3H796	G3H7C4	Sonic hedgehog protein.	Bone morphogenetic protein 4.	0.605
I79_006225	Ptch1	G3H796	G3IJP5	Sonic hedgehog protein.	Protein patched-like 1.	0.983
I79_006225	Smo	G3H796	G3GZ55	Sonic hedgehog protein.	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.831
I79_006254	I79_006225	G3H7C4	G3H796	Bone morphogenetic protein 4.	Sonic hedgehog protein.	0.605
I79_006254	Ihh	G3H7C4	G3HWF8	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.593
I79_006254	Ptch1	G3H7C4	G3IJP5	Bone morphogenetic protein 4.	Protein patched-like 1.	0.561
I79_006254	Smo	G3H7C4	G3GZ55	Bone morphogenetic protein 4.	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.557
I79_012894	I79_001046	G3HQ06	G3GTQ9	Transcription factor AP-2 beta.	Neurofibromin.	0.751
I79_013660	Pdgfrb	G3HS34	G3HS35	Beta-type platelet-derived growth factor receptor.	Beta-type platelet-derived growth factor receptor.	0.892
I79_024483	I79_025625	G3IKT0	G3INT6	Polycystin-2.	Polycystin-2.	0.897
I79_024483	Smo	G3IKT0	G3GZ55	Polycystin-2.	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.401
I79_025625	I79_024483	G3INT6	G3IKT0	Polycystin-2.	Polycystin-2.	0.897