STRINGSTRING
Ctnnb1 Ctnnb1 I79_006881 I79_006881 Ncoa3 Ncoa3 I79_006792 I79_006792 Dag1 Dag1 Gna13 Gna13 Vangl2 Vangl2 Sema5a Sema5a I79_006254 I79_006254 I79_006225 I79_006225 Igf1 Igf1 Med1 Med1 Sall1 Sall1 I79_005573 I79_005573 Mgp Mgp Kdm5b Kdm5b Msx2 Msx2 Gli2 Gli2 Edn1 Edn1 Cxcr4 Cxcr4 I79_003312 I79_003312 Csmd1 Csmd1 I79_002659 I79_002659 Src Src Agt Agt Dlg5 Dlg5 I79_002099 I79_002099 Tgfbr2 Tgfbr2 I79_001487 I79_001487 ctsz ctsz I79_026151 I79_026151 I79_026146 I79_026146 I79_025795 I79_025795 Myc Myc Wnt9b Wnt9b I79_025625 I79_025625 I79_025487 I79_025487 Dspp Dspp I79_025450 I79_025450 I79_025338 I79_025338 Hhex Hhex I79_025180 I79_025180 I79_025170 I79_025170 Pak1 Pak1 I79_024593 I79_024593 I79_024483 I79_024483 Rbm15 Rbm15 I79_024447 I79_024447 I79_024446 I79_024446 Ppp1ca Ppp1ca Gzf1 Gzf1 I79_017861 I79_017861 I79_017833 I79_017833 Fat4 Fat4 I79_017230 I79_017230 Pkhd1 Pkhd1 Fut1 Fut1 Gpsm3 Gpsm3 Dicer1 Dicer1 Nrp1 Nrp1 Srf Srf Npm3 Npm3 Foxa2 Foxa2 Rdh10 Rdh10 I79_015544 I79_015544 I79_015321 I79_015321 Ihh Ihh Plxnd1 Plxnd1 Gli3 Gli3 Smad4 Smad4 Ahr Ahr Spry1 Spry1 I79_013795 I79_013795 Tnc Tnc Timeless Timeless I79_013395 I79_013395 Ddr1 Ddr1 I79_012727 I79_012727 Ctnnbip1 Ctnnbip1 I79_024203 I79_024203 I79_024202 I79_024202 Fgfr2 Fgfr2 Ptch1 Ptch1 I79_023738 I79_023738 Pitx2 Pitx2 Csf1 Csf1 Ar Ar Gbx2 Gbx2 Celsr1 Celsr1 Pax8 Pax8 I79_001484 I79_001484 Wnt5a Wnt5a Phb2 Phb2 I79_001232 I79_001232 Pxn Pxn Dll4 Dll4 I79_021445 I79_021445 I79_021446 I79_021446 I79_021447 I79_021447 I79_021448 I79_021448 I79_021564 I79_021564 I79_021721 I79_021721 I79_021890 I79_021890 Vdr Vdr Six1 Six1 I79_022034 I79_022034 I79_022078 I79_022078 I79_022205 I79_022205 ilk ilk Foxf1 Foxf1 I79_000973 I79_000973 I79_001073 I79_001073 Tbx3 Tbx3 Sema3e Sema3e Clic4 Clic4 Stk4 Stk4 Nfatc3 Nfatc3 Esrp2 Esrp2 Pbx1 Pbx1 Sox2 Sox2 Gdnf Gdnf Mks1 Mks1 I79_010613 I79_010613 Pml Pml Wnt4 Wnt4 Tmtc3 Tmtc3 I79_010279 I79_010279 Acvr1 Acvr1 Lama5 Lama5 I79_009708 I79_009708 I79_009699 I79_009699 Pgf Pgf I79_009343 I79_009343 I79_009314 I79_009314 Fgf1 Fgf1 Tgfb1 Tgfb1 I79_019973 I79_019973 Epha2 Epha2 I79_019695 I79_019695 Foxa1 Foxa1 Col4a1 Col4a1 I79_019286 I79_019286 Cxcl12 Cxcl12 I79_019149 I79_019149 Wnt1 Wnt1 Hnf1b Hnf1b Tbx20 Tbx20 Lrp5 Lrp5 Btrc Btrc I79_018593 I79_018593 Areg Areg I79_021155 I79_021155 Ppp3r1 Ppp3r1 I79_008527 I79_008527 Hoxa11 Hoxa11 Nfatc1 Nfatc1 CgPICR_019990 CgPICR_019990 Pkd1 Pkd1 Tfap2c Tfap2c Bmp7 Bmp7 Lrp6 Lrp6 I79_007641 I79_007641 Greb1 Greb1 Ext1 Ext1 I79_007063 I79_007063 Hhip Hhip Tcf21 Tcf21 Tbx2 Tbx2 Lhx1 Lhx1 Ednra Ednra
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ctnnb1Catenin beta-1. (781 aa)
I79_006881CUB and sushi domain-containing protein 2. (3527 aa)
Ncoa3Nuclear receptor coactivator 3. (1211 aa)
I79_006792DUF1518 domain-containing protein. (200 aa)
Dag1Dystroglycan. (893 aa)
Gna13Guanine nucleotide-binding protein subunit alpha-13. (282 aa)
Vangl2Vang-like protein. (521 aa)
Sema5aSemaphorin-5A. (1046 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
I79_006225Sonic hedgehog protein. (226 aa)
Igf1Insulin-like growth factor I. (75 aa)
Med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1581 aa)
Sall1Sal-like protein 1. (1294 aa)
I79_005573Secreted frizzled-related protein 2. (268 aa)
MgpMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (94 aa)
Kdm5bLysine-specific demethylase 5B. (748 aa)
Msx2Homeobox protein MSX-2. (267 aa)
Gli2Zinc finger protein GLI2. (1547 aa)
Edn1Endothelin-1. (202 aa)
Cxcr4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (290 aa)
I79_003312CUB and sushi domain-containing protein 1. (3110 aa)
Csmd1CUB and sushi domain-containing protein 1. (106 aa)
I79_002659High mobility group protein HMGI-C. (103 aa)
SrcTyrosine-protein kinase. (536 aa)
AgtAngiotensinogen; Belongs to the serpin family. (477 aa)
Dlg5Disks large-like 5; Belongs to the MAGUK family. (1873 aa)
I79_002099Vascular endothelial growth factor receptor 1. (115 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
I79_001487Progesterone receptor. (741 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (306 aa)
I79_026151ETS translocation variant 4. (69 aa)
I79_026146ETS translocation variant 4. (95 aa)
I79_025795Vitamin D3 receptor. (86 aa)
MycMyc proto-oncogene protein. (281 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
I79_025625Polycystin-2. (318 aa)
I79_025487Disks large-like 5. (92 aa)
DsppDentin sialophosphoprotein. (859 aa)
I79_025450Disks large-like 5. (167 aa)
I79_025338Disks large-like 5. (203 aa)
HhexHematopoietically-expressed homeobox protein Hhex. (98 aa)
I79_025180Disks large-like 5. (144 aa)
I79_025170Slit-like 2 protein. (345 aa)
Pak1Serine/threonine-protein kinase PAK 1. (325 aa)
I79_024593Uncharacterized protein. (194 aa)
I79_024483Polycystin-2. (192 aa)
Rbm15Putative RNA-binding protein 15. (912 aa)
I79_024447Disks large-like 5. (99 aa)
I79_024446Disks large-like 5. (162 aa)
Ppp1caSerine/threonine-protein phosphatase PP1-alpha catalytic subunit. (148 aa)
Gzf1GDNF-inducible zinc finger protein 1. (701 aa)
I79_017861Solute carrier family 12 member 2. (706 aa)
I79_017833Lymphoid enhancer-binding factor 1. (276 aa)
Fat4Protocadherin Fat 4. (5152 aa)
I79_017230Fibrocystin. (1423 aa)
Pkhd1Fibrocystin. (176 aa)
Fut1Galactoside 2-alpha-L-fucosyltransferase 1. (954 aa)
Gpsm3Neurogenic locus notch-like protein 4. (1797 aa)
Dicer1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
SrfSerum response factor. (361 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Foxa2Hepatocyte nuclear factor 3-beta. (430 aa)
Rdh10Retinol dehydrogenase 10. (65 aa)
I79_015544Meckelin. (749 aa)
I79_015321Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (243 aa)
IhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (918 aa)
Plxnd1Plexin-D1. (612 aa)
Gli3Zinc finger protein GLI3. (1582 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
AhrAryl hydrocarbon receptor. (247 aa)
Spry1Protein sprouty-like 1. (313 aa)
I79_013795Disks large-like 5. (96 aa)
TncTenascin. (2202 aa)
TimelessProtein timeless-like. (1200 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
Ddr1Epithelial discoidin domain-containing receptor 1 isoform 1. (910 aa)
I79_012727Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (441 aa)
Ctnnbip1Beta-catenin-interacting protein 1. (81 aa)
I79_024203Sal-like protein 1. (121 aa)
I79_024202Sal-like protein 1. (825 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
Ptch1Protein patched-like 1. (1114 aa)
I79_023738Cadherin EGF LAG seven-pass G-type receptor 1. (979 aa)
Pitx2Homeobox protein. (322 aa)
Csf1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (552 aa)
ArAndrogen receptor. (517 aa)
Gbx2Homeobox protein GBX-2. (222 aa)
Celsr1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1009 aa)
Pax8Paired box protein Pax-8. (452 aa)
I79_00148465 kDa Yes-associated protein. (257 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Phb2Prohibitin-2. (396 aa)
I79_001232Paxillin; Belongs to the phospholipase A2 family. (642 aa)
PxnPaxillin. (388 aa)
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
I79_021445Disks large-like 5. (294 aa)
I79_021446Disks large-like 5. (133 aa)
I79_021447Disks large-like 5. (129 aa)
I79_021448Disks large-like 5. (270 aa)
I79_021564Pro-epidermal growth factor. (699 aa)
I79_021721Protocadherin-16. (3015 aa)
I79_021890Disks large-like 5. (101 aa)
VdrVitamin D3 receptor. (372 aa)
Six1Homeobox protein SIX1. (284 aa)
I79_022034Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
I79_022078Homeobox protein Nkx-2.1. (190 aa)
I79_022205Disks large-like 5. (99 aa)
ilkIntegrin-linked protein kinase. (452 aa)
Foxf1Forkhead box protein F1. (320 aa)
I79_000973Transcription factor SOX-10. (360 aa)
I79_001073C-C motif chemokine. (72 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
Sema3eSemaphorin-3E; Belongs to the semaphorin family. (777 aa)
Clic4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (211 aa)
Stk4Serine/threonine-protein kinase 4. (487 aa)
Nfatc3Nuclear factor of activated T-cells, cytoplasmic 3. (1075 aa)
Esrp2Epithelial splicing regulatory protein 2. (697 aa)
Pbx1Pre-B-cell leukemia transcription factor 1. (325 aa)
Sox2Transcription factor SOX-2. (273 aa)
GdnfGlial cell line-derived neurotrophic factor. (160 aa)
Mks1Meckel syndrome type 1 protein-like. (561 aa)
I79_010613Transcription factor AP-2 gamma. (236 aa)
PmlPutative transcription factor PML. (540 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (288 aa)
Tmtc3Transmembrane and TPR repeat-containing protein 3. (916 aa)
I79_010279Epithelial splicing regulatory protein 1. (677 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Lama5Laminin subunit alpha-5. (3735 aa)
I79_009708Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (332 aa)
I79_009699GREB1-like protein. (1598 aa)
PgfPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
I79_009343N-myc proto-oncogene protein. (316 aa)
I79_009314Tyrosine-protein kinase receptor Tie-1. (954 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_019973Disks large-like 5. (219 aa)
Epha2Ephrin type-A receptor 2. (942 aa)
I79_019695Fibrocystin. (1076 aa)
Foxa1Hepatocyte nuclear factor 3-alpha. (434 aa)
Col4a1Collagen alpha-1(IV) chain. (1614 aa)
I79_019286Androgen receptor. (295 aa)
Cxcl12Stromal cell-derived factor 1. (89 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Hnf1bHepatocyte nuclear factor 1-beta. (593 aa)
Tbx20T-box transcription factor TBX20. (445 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
BtrcF-box/WD repeat-containing protein 1A. (488 aa)
I79_018593Disks large-like 5. (121 aa)
AregAmphiregulin. (230 aa)
I79_021155Paired box protein Pax-2. (503 aa)
Ppp3r1Calcineurin subunit B type 1-like protein. (165 aa)
I79_008527Nuclear factor of activated T-cells, cytoplasmic 4. (849 aa)
Hoxa11Homeobox protein Hox-A11. (250 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa)
CgPICR_019990Persephin. (157 aa)
Pkd1Polycystin-1. (3717 aa)
Tfap2cTranscription factor AP-2 gamma. (463 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Greb1Protein GREB1. (1972 aa)
Ext1Exostosin-1. (388 aa)
I79_007063Hepatocyte growth factor receptor. (1222 aa)
HhipHedgehog-interacting protein. (671 aa)
Tcf21Transcription factor 21. (179 aa)
Tbx2T-box transcription factor TBX2. (234 aa)
Lhx1LIM/homeobox protein Lhx1. (84 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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