STRINGSTRING
I79_015624 I79_015624 Bak1 Bak1 I79_000092 I79_000092 Mitf Mitf I79_000368 I79_000368 Jag1 Jag1 Lyrm9 Lyrm9 Rac1 Rac1 Src Src I79_002778 I79_002778 Bmpr2 Bmpr2 Traf6 Traf6 Cspg4 Cspg4 Mmp2 Mmp2 Slc34a1 Slc34a1 I79_004409 I79_004409 Gja5 Gja5 Ctsk Ctsk I79_004580 I79_004580 F2r F2r Igfbp5 Igfbp5 Lrrk1 Lrrk1 Igf1 Igf1 Acp5 Acp5 CgPICR_019686 CgPICR_019686 Mmp9 Mmp9 Ctnnb1 Ctnnb1 Ednra Ednra Cav1 Cav1 Ncdn Ncdn Ptn Ptn Ext1 Ext1 Gsk3b Gsk3b I79_007514 I79_007514 Mef2c Mef2c I79_007641 I79_007641 Lrp6 Lrp6 I79_007693 I79_007693 Hoxa3 Hoxa3 I79_008633 I79_008633 Tgfbr3 Tgfbr3 I79_009030 I79_009030 I79_009314 I79_009314 Tgfb3 Tgfb3 I79_009796 I79_009796 Tnfsf11 Tnfsf11 I79_010074 I79_010074 I79_010330 I79_010330 Rab7a Rab7a I79_011304 I79_011304 Nfatc3 Nfatc3 Cbs Cbs Crb1 Crb1 I79_011762 I79_011762 I79_011943 I79_011943 Sema3c Sema3c I79_012336 I79_012336 Atp7a Atp7a Notch2 Notch2 I79_012814 I79_012814 I79_012815 I79_012815 Chd7 Chd7 Acvr2b Acvr2b Lipa Lipa I79_013395 I79_013395 Il23a Il23a Ahr Ahr I79_014935 I79_014935 Atg5 Atg5 Htr1b Htr1b I79_015223 I79_015223 Ihh Ihh CgPICR_014700 CgPICR_014700 Npm3 Npm3 Hif1a Hif1a Lif Lif Tcirg1 Tcirg1 Lrp5 Lrp5 Lgr4 Lgr4 I79_019149 I79_019149 Epha2 Epha2 Nox4 Nox4 Hnrnpul1 Hnrnpul1 Tgfb1 Tgfb1 Enpp1 Enpp1 I79_020752 I79_020752 Timp1 Timp1 Flna Flna Acvrl1 Acvrl1 Rbpj Rbpj Dll4 Dll4 Tpp1 Tpp1 Wnt16 Wnt16 Vdr Vdr I79_022023 I79_022023 Adrb2 Adrb2 I79_022271 I79_022271 Epas1 Epas1 I79_022685 I79_022685 Bsx Bsx I79_023010 I79_023010 Gpr55 Gpr55 I79_024370 I79_024370 Tph1 Tph1 I79_024533 I79_024533 Umod Umod Capn1 Capn1 I79_025428 I79_025428 I79_025795 I79_025795 Rspo3 Rspo3 Dbh Dbh Gja1 Gja1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_015624Thrombospondin-4. (960 aa)
Bak1Bcl-2-likeous antagonist/killer. (209 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
MitfMicrophthalmia-associated transcription factor. (474 aa)
I79_000368Microphthalmia-associated transcription factor. (106 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
Lyrm9Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1115 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (148 aa)
SrcTyrosine-protein kinase. (536 aa)
I79_002778Macrophage asialoglycoprotein-binding protein. (527 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (508 aa)
Cspg4Chondroitin sulfate proteoglycan 4. (2323 aa)
Mmp272 kDa type IV collagenase. (662 aa)
Slc34a1Sodium-dependent phosphate transport protein 2A. (629 aa)
I79_004409Sorting nexin-10. (214 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
CtskCathepsin K. (87 aa)
I79_004580Cathepsin K. (68 aa)
F2rProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (396 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
Lrrk1Leucine-rich repeat serine/threonine-protein kinase 1. (396 aa)
Igf1Insulin-like growth factor I. (75 aa)
Acp5Tartrate-resistant acid phosphatase type 5. (330 aa)
CgPICR_019686Ras-related protein Rab-3D-like protein. (219 aa)
Mmp9Matrix metalloproteinase-9. (710 aa)
Ctnnb1Catenin beta-1. (781 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
NcdnNeurochondrin. (712 aa)
PtnPleiotrophin. (168 aa)
Ext1Exostosin-1. (388 aa)
Gsk3bGlycogen synthase kinase-3 beta. (328 aa)
I79_007514Growth/differentiation factor 5. (253 aa)
Mef2cMyocyte-specific enhancer factor 2C. (465 aa)
I79_007641Low-density lipoprotein receptor-related protein 6. (543 aa)
Lrp6Low-density lipoprotein receptor-related protein 6. (565 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Hoxa3Homeobox protein Hox-A3. (286 aa)
I79_008633Integrin alpha-4; Belongs to the integrin alpha chain family. (441 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
I79_009030T-box transcription factor TBX1. (293 aa)
I79_009314Tyrosine-protein kinase receptor Tie-1. (954 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
I79_009796Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (697 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
I79_010074Tripeptidyl-peptidase 1. (278 aa)
I79_010330Hepatocyte nuclear factor 1-alpha. (668 aa)
Rab7aRas-related protein Rab-7a. (207 aa)
I79_011304Parathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (626 aa)
Nfatc3Nuclear factor of activated T-cells, cytoplasmic 3. (1075 aa)
CbsCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (561 aa)
Crb1Crumbs-like 1. (989 aa)
I79_011762Crumbs-like 1. (107 aa)
I79_011943Semaphorin-3C. (86 aa)
Sema3cSemaphorin-3C; Belongs to the semaphorin family. (493 aa)
I79_012336Protein tyrosine kinase 2 beta. (53 aa)
Atp7aCopper-transporting ATPase 1. (1457 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
I79_012814Chromodomain-helicase-DNA-binding protein 7. (100 aa)
I79_012815Chromodomain-helicase-DNA-binding protein 7. (150 aa)
Chd7Chromodomain-helicase-DNA-binding protein 7. (615 aa)
Acvr2bSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (559 aa)
LipaLipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
I79_013395Matrix metalloproteinase-14. (539 aa)
Il23aInterleukin-23 subunit alpha. (196 aa)
AhrAryl hydrocarbon receptor. (247 aa)
I79_014935Chondroitin sulfate proteoglycan 4. (849 aa)
Atg5Autophagy protein 5; Involved in autophagic vesicle formation. (147 aa)
Htr1b5-hydroxytryptamine receptor 1B. (386 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
IhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (918 aa)
CgPICR_014700C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
LifLeukemia inhibitory factor-like protein. (158 aa)
Tcirg1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (835 aa)
Lrp5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
Lgr4Leucine-rich repeat-containing G-protein coupled receptor 4. (231 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
Epha2Ephrin type-A receptor 2. (942 aa)
Nox4NADPH oxidase 4. (130 aa)
Hnrnpul1Heterogeneous nuclear ribonucleoprotein U-like protein 1. (1566 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
Enpp1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (906 aa)
I79_020752Chondroitin sulfate proteoglycan 4. (1364 aa)
Timp1Metalloproteinase inhibitor 1-like protein. (203 aa)
FlnaFilamin-A. (2488 aa)
Acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (578 aa)
Tpp1Tripeptidyl-peptidase 1. (320 aa)
Wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
VdrVitamin D3 receptor. (372 aa)
I79_022023Arginase-1; Belongs to the arginase family. (281 aa)
Adrb2Beta-2 adrenergic receptor. (337 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
Epas1Endothelial PAS domain-containing protein 1. (878 aa)
I79_022685Dopamine beta-hydroxylase. (534 aa)
BsxBrain-specific homeobox protein-like. (89 aa)
I79_023010Latent-transforming growth factor beta-binding protein 3. (624 aa)
Gpr55Putative G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (332 aa)
I79_024370Microphthalmia-associated transcription factor. (185 aa)
Tph1Tryptophan 5-hydroxylase 1. (115 aa)
I79_024533Tryptophan 5-hydroxylase 1. (131 aa)
UmodUromodulin. (618 aa)
Capn1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (740 aa)
I79_025428Secreted phosphoprotein 24. (97 aa)
I79_025795Vitamin D3 receptor. (86 aa)
Rspo3R-spondin-3. (81 aa)
DbhDopamine beta-hydroxylase. (117 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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