(15 nodes) Forebrain morphogenesis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_006693	Intraflagellar transport protein 88-like. (533 aa)
	I79_003741	Dual oxidase 2. (1367 aa)
	Smo	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	I79_001046	Neurofibromin. (2164 aa)
	Hhex	Hematopoietically-expressed homeobox protein Hhex. (98 aa)
	I79_022486	GS homeobox 2. (100 aa)
	I79_019149	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
	I79_018586	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN. (345 aa)
	Npm3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
	Uchl5	Ubiquitin carboxyl-terminal hydrolase. (329 aa)
	Otx2	Homeobox protein OTX2. (289 aa)
	Sox2	Transcription factor SOX-2. (273 aa)
	Gak	Cyclin G-associated kinase. (1307 aa)
	I79_008642	Homeobox protein OTX1. (339 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gak	I79_018586	G3HEE4	G3I540	Cyclin G-associated kinase.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	0.569
Hhex	Otx2	G3IN11	G3HRU9	Hematopoietically-expressed homeobox protein Hhex.	Homeobox protein OTX2.	0.821
I79_001046	I79_018586	G3GTQ9	G3I540	Neurofibromin.	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	0.528
I79_006693	Smo	G3H8J1	G3GZ55	Intraflagellar transport protein 88-like.	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.593
I79_018586	Gak	G3I540	G3HEE4	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Cyclin G-associated kinase.	0.569
I79_018586	I79_001046	G3I540	G3GTQ9	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN.	Neurofibromin.	0.528
Otx2	Hhex	G3HRU9	G3IN11	Homeobox protein OTX2.	Hematopoietically-expressed homeobox protein Hhex.	0.821
Otx2	Sox2	G3HRU9	G3HJZ4	Homeobox protein OTX2.	Transcription factor SOX-2.	0.490
Smo	I79_006693	G3GZ55	G3H8J1	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Intraflagellar transport protein 88-like.	0.593
Smo	Wnt5a	G3GZ55	G3GUT6	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.510
Sox2	Otx2	G3HJZ4	G3HRU9	Transcription factor SOX-2.	Homeobox protein OTX2.	0.490
Wnt5a	Smo	G3GUT6	G3GZ55	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Smoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family.	0.510