(36 nodes) Nuclear androgen receptor binding network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Smarca4	Putative global transcription activator SNF2L4. (1614 aa)
	Rnf14	RBR-type E3 ubiquitin transferase. (420 aa)
	Foxh1	Forkhead box protein H1. (367 aa)
	I79_012926	Death domain-associated protein 6. (393 aa)
	Psmc3ip	Homologous-pairing protein 2-like. (217 aa)
	I79_010851	Lysine-specific demethylase 3A. (1232 aa)
	Kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (750 aa)
	I79_009902	Pre-mRNA-processing factor 6. (368 aa)
	I79_003898	RING finger protein 6. (477 aa)
	H671_3g8832	E3 ubiquitin-protein ligase. (169 aa)
	I79_003904	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific. (2318 aa)
	Arid5a	AT-rich interactive domain-containing protein 5A. (588 aa)
	Snw1	SNW domain-containing protein 1. (536 aa)
	Rnf4	RING finger protein 4. (128 aa)
	I79_006381	Lysine-specific demethylase 4C. (520 aa)
	Kdm4c	Lysine-specific demethylase 4C. (209 aa)
	I79_006552	WD repeat domain phosphoinositide-interacting protein 1. (444 aa)
	I79_006792	DUF1518 domain-containing protein. (200 aa)
	Ncoa3	Nuclear receptor coactivator 3. (1211 aa)
	Pkn1	Serine/threonine-protein kinase N1; Belongs to the G-protein coupled receptor 2 family. (1696 aa)
	Calr	Calreticulin. (417 aa)
	Ddx5	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (615 aa)
	I79_007385	E3 SUMO-protein ligase PIAS2. (116 aa)
	Pias2	E3 SUMO-protein ligase PIAS2. (157 aa)
	Prmt2	Protein arginine N-methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (445 aa)
	I79_024164	Tripartite motif-containing protein 68. (455 aa)
	Ar	Androgen receptor. (517 aa)
	I79_021114	Pre-mRNA-processing factor 6. (535 aa)
	Tcf21	Transcription factor 21. (179 aa)
	I79_019286	Androgen receptor. (295 aa)
	Daxx	Death domain-associated protein 6. (708 aa)
	Foxp1	Forkhead box protein P1. (696 aa)
	Tmf1	TATA element modulatory factor. (1094 aa)
	Foxp2	Forkhead box protein P2. (492 aa)
	Rnf6	E3 ubiquitin-protein ligase. (666 aa)
	Ep300	Histone acetyltransferase p300. (2415 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ar	Calr	G3IGU9	G3HCX8	Androgen receptor.	Calreticulin.	0.456
Ar	Daxx	G3IGU9	G3I6W2	Androgen receptor.	Death domain-associated protein 6.	0.466
Ar	Ep300	G3IGU9	G3I534	Androgen receptor.	Histone acetyltransferase p300.	0.658
Ar	I79_006381	G3IGU9	G3H7P5	Androgen receptor.	Lysine-specific demethylase 4C.	0.435
Ar	I79_006792	G3IGU9	G3H8T1	Androgen receptor.	DUF1518 domain-containing protein.	0.790
Ar	I79_019286	G3IGU9	G3I705	Androgen receptor.	Androgen receptor.	0.915
Ar	Kdm1a	G3IGU9	G3HIN6	Androgen receptor.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.770
Ar	Kdm4c	G3IGU9	G3H7P6	Androgen receptor.	Lysine-specific demethylase 4C.	0.435
Ar	Ncoa3	G3IGU9	G3H8T2	Androgen receptor.	Nuclear receptor coactivator 3.	0.790
Ar	Pkn1	G3IGU9	G3HD16	Androgen receptor.	Serine/threonine-protein kinase N1; Belongs to the G-protein coupled receptor 2 family.	0.582
Ar	Rnf14	G3IGU9	G3HYD1	Androgen receptor.	RBR-type E3 ubiquitin transferase.	0.661
Calr	Ar	G3HCX8	G3IGU9	Calreticulin.	Androgen receptor.	0.456
Calr	I79_019286	G3HCX8	G3I705	Calreticulin.	Androgen receptor.	0.456
Daxx	Ar	G3I6W2	G3IGU9	Death domain-associated protein 6.	Androgen receptor.	0.466
Daxx	I79_019286	G3I6W2	G3I705	Death domain-associated protein 6.	Androgen receptor.	0.457
Daxx	Rnf4	G3I6W2	G3I0J7	Death domain-associated protein 6.	RING finger protein 4.	0.519
Ddx5	Ep300	G3HCT4	G3I534	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Histone acetyltransferase p300.	0.679
Ddx5	I79_006792	G3HCT4	G3H8T1	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	DUF1518 domain-containing protein.	0.403
Ddx5	I79_009902	G3HCT4	G3HH07	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Pre-mRNA-processing factor 6.	0.653
Ddx5	I79_021114	G3HCT4	G3IBT1	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Pre-mRNA-processing factor 6.	0.653