STRINGSTRING
I79_000092 I79_000092 I79_002759 I79_002759 Trh Trh I79_000592 I79_000592 I79_001274 I79_001274 Znf384 Znf384 I79_001476 I79_001476 I79_001592 I79_001592 Prkce Prkce Rac1 Rac1 Abat Abat Frmd4a Frmd4a Pdx1 Pdx1 Ghrl Ghrl Gpr39 Gpr39 I79_003212 I79_003212 Gja1 Gja1 I79_025828 I79_025828 I79_025502 I79_025502 Arf6 Arf6 Apbb1 Apbb1 Pla2g6 Pla2g6 Irs2 Irs2 H671_3g10186 H671_3g10186 Arrb1 Arrb1 Tcf7l2 Tcf7l2 Osbp Osbp Phpt1 Phpt1 I79_023112 I79_023112 Lrrc8a Lrrc8a Rab34 Rab34 Exoc1 Exoc1 I79_022295 I79_022295 I79_022284 I79_022284 Atp13a2 Atp13a2 I79_022271 I79_022271 Jak2 Jak2 Pfkm Pfkm Hcar2 Hcar2 I79_020783 I79_020783 I79_020509 I79_020509 Tgfb1 Tgfb1 I79_020279 I79_020279 C2cd2l C2cd2l I79_020099 I79_020099 Myom1 Myom1 I79_019979 I79_019979 Mylk3 Mylk3 Myo18a Myo18a Stx4 Stx4 Nr1h2 Nr1h2 I79_018871 I79_018871 Tardbp Tardbp Apbb3 Apbb3 I79_018615 I79_018615 I79_018313 I79_018313 I79_018194 I79_018194 C1qtnf12 C1qtnf12 Gpr68 Gpr68 I79_017694 I79_017694 I79_017638 I79_017638 I79_017637 I79_017637 Nadk Nadk Eif1b Eif1b Tlr4 Tlr4 I79_017077 I79_017077 Trpm4 Trpm4 Pard6a Pard6a Hif1a Hif1a Kcnn4 Kcnn4 Nr0b2 Nr0b2 I79_015980 I79_015980 Adora2a Adora2a Ins Ins Oga Oga Wls Wls Ezr Ezr A1cf A1cf Lrp1 Lrp1 I79_014954 I79_014954 PPARG PPARG Gper1 Gper1 Rph3al Rph3al Doc2b Doc2b I79_013946 I79_013946 I79_013817 I79_013817 Ppard Ppard Sri Sri I79_012966 I79_012966 Vamp8 Vamp8 Acsl4 Acsl4 I79_011990 I79_011990 Gck Gck Abcg1 Abcg1 Glp1r Glp1r Glul-2 Glul-2 Ptpn23 Ptpn23 C1qtnf3 C1qtnf3 I79_010883 I79_010883 Mcu Mcu Golph3 Golph3 I79_010330 I79_010330 I79_010135 I79_010135 I79_010073 I79_010073 Oxct1 Oxct1 I79_009991 I79_009991 Vsnl1 Vsnl1 Vegfc Vegfc Serp1 Serp1 Glul Glul Tgfb3 Tgfb3 Tmed10 Tmed10 Exph5 Exph5 I79_008941 I79_008941 I79_008836 I79_008836 Gpld1 Gpld1 Pck2 Pck2 Baiap3 Baiap3 Sybu Sybu Ncoa6 Ncoa6 Ttn Ttn Sirt1 Sirt1 I79_007067 I79_007067 Rbp4 Rbp4 Lrrc3 Lrrc3 I79_006760 I79_006760 Glrx Glrx I79_006180 I79_006180 Igf1 Igf1 Sytl4 Sytl4 I79_005742 I79_005742 Fgb Fgb Fga Fga Capn10 Capn10 Ankrd1 Ankrd1 I79_004874 I79_004874 F2rl1 F2rl1 I79_004626 I79_004626 Golph3l Golph3l Sec24a Sec24a Psmd9 Psmd9 I79_004285 I79_004285 I79_004035 I79_004035 Blk Blk Slc30a8 Slc30a8 Pfkfb2 Pfkfb2 Myh10 Myh10 I79_000010 I79_000010 Ucn3 Ucn3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
I79_002759Neuroligin-2. (635 aa)
TrhPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (247 aa)
I79_000592Peripheral plasma membrane protein CASK; Belongs to the MAGUK family. (742 aa)
I79_001274Rap guanine nucleotide exchange factor 4. (761 aa)
Znf384Zinc finger protein 384. (612 aa)
I79_001476Collagenase 3. (300 aa)
I79_001592Protein kinase C epsilon type. (163 aa)
PrkceProtein kinase C epsilon type. (137 aa)
Rac1Ras-related C3 botulinum toxin substrate 1. (148 aa)
Abat4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa)
Frmd4aFERM domain-containing protein 4A. (738 aa)
Pdx1Pancreas/duodenum homeobox protein 1. (283 aa)
GhrlAppetite-regulating hormone. (100 aa)
Gpr39G-protein coupled receptor 39; Belongs to the G-protein coupled receptor 1 family. (289 aa)
I79_003212G-protein coupled receptor 39. (151 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
I79_025828Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (184 aa)
I79_025502Adenylate cyclase type 8. (333 aa)
Arf6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
Apbb1Amyloid beta A4 protein-binding family B member 1. (530 aa)
Pla2g685 kDa calcium-independent phospholipase A2. (77 aa)
Irs2Insulin receptor substrate 2. (465 aa)
H671_3g10186Olfactory receptor. (320 aa)
Arrb1Beta-arrestin-1. (422 aa)
Tcf7l2Transcription factor 7-like 1. (73 aa)
OsbpOxysterol-binding protein; Belongs to the OSBP family. (736 aa)
Phpt114 kDa phosphohistidine phosphatase. (124 aa)
I79_023112Glutamine synthetase; Belongs to the glutamine synthetase family. (130 aa)
Lrrc8aLeucine-rich repeat-containing protein 8A. (810 aa)
Rab34Ras-related protein Rab-34. (259 aa)
Exoc1Exocyst complex component 1-like protein. (880 aa)
I79_022295Dynamin-1-like protein. (310 aa)
I79_022284Putative cation-transporting ATPase 13A2. (515 aa)
Atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (578 aa)
I79_022271Ras-related C3 botulinum toxin substrate 2. (178 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
PfkmATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
Hcar2Hydroxycarboxylic acid receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
I79_020783Transcription factor 7-like 2. (451 aa)
I79_020509Myomesin-1. (449 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
I79_020279Dynein light chain. (89 aa)
C2cd2lC2 domain-containing protein 2-like. (508 aa)
I79_020099C2 domain-containing protein 2-like. (218 aa)
Myom1Myomesin-1. (81 aa)
I79_019979Myomesin-1. (628 aa)
Mylk3Vacuolar protein sorting-associated protein 35. (1427 aa)
Myo18aMyosin-XVIIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2050 aa)
Stx4Syntaxin-4; Belongs to the syntaxin family. (298 aa)
Nr1h2Oxysterols receptor LXR-beta. (445 aa)
I79_018871TAR DNA-binding protein 43. (213 aa)
TardbpTAR DNA-binding protein 43. (199 aa)
Apbb3Amyloid beta A4 protein-binding family B member 3. (187 aa)
I79_018615DNA-binding protein RFX6. (582 aa)
I79_018313Anoctamin. (466 aa)
I79_018194Protein FAM132A. (127 aa)
C1qtnf12Protein FAM132A. (61 aa)
Gpr68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
I79_017694Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform. (178 aa)
I79_017638Transient receptor potential cation channel subfamily A member 1. (312 aa)
I79_017637Transient receptor potential cation channel subfamily A member 1. (291 aa)
NadkNAD kinase. (445 aa)
Eif1bRab effector MyRIP. (919 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
I79_017077Acetoacetyl-CoA synthetase. (634 aa)
Trpm4Transient receptor potential cation channel subfamily M member 4. (315 aa)
Pard6aPartitioning defective 6-like alpha. (264 aa)
Hif1aHypoxia-inducible factor 1 alpha. (820 aa)
Kcnn4Intermediate conductance calcium-activated potassium channel protein 4. (54 aa)
Nr0b2Nuclear receptor subfamily 0 group B member 2. (260 aa)
I79_015980Leptin receptor. (533 aa)
Adora2aAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
InsMultifunctional fusion protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver; Belongs to the ferritin family. (248 aa)
OgaBifunctional protein NCOAT. (842 aa)
WlsIntegral membrane protein GPR177. (166 aa)
EzrEzrin. (586 aa)
A1cfAPOBEC1 complementation factor. (1001 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
I79_014954Autophagy-related protein 7. (439 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Rph3alRab effector Noc2. (300 aa)
Doc2bDouble C2-like domain-containing protein beta. (413 aa)
I79_013946Long-chain-fatty-acid--CoA ligase 4. (289 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
SriSorcin. (117 aa)
I79_012966Anoctamin. (532 aa)
Vamp8Vesicle-associated membrane protein 8. (101 aa)
Acsl4Long-chain-fatty-acid--CoA ligase 4. (274 aa)
I79_011990Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (220 aa)
GckPhosphotransferase. (465 aa)
Abcg1ATP-binding cassette sub-family G member 1. (647 aa)
Glp1rGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (437 aa)
Glul-2Glutamine synthetase. (373 aa)
Ptpn23Tyrosine-protein phosphatase non-receptor type 23. (1639 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
I79_010883Gastric inhibitory polypeptide. (205 aa)
McuCoiled-coil domain-containing protein 109A. (219 aa)
Golph3Golgi phosphoprotein 3. (223 aa)
I79_010330Hepatocyte nuclear factor 1-alpha. (668 aa)
I79_010135ADP-ribosylation factor 1. (72 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
Oxct1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (520 aa)
I79_009991ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (152 aa)
Vsnl1Visinin-like protein 1. (191 aa)
VegfcVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
Serp1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa)
GlulGlutamine synthetase; Belongs to the glutamine synthetase family. (297 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
Tmed10Transmembrane emp24 domain-containing protein 10; Belongs to the EMP24/GP25L family. (130 aa)
Exph5Exophilin-5. (506 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
I79_008836Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (117 aa)
Gpld1Phosphatidylinositol-glycan-specific phospholipase D. (778 aa)
Pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
Baiap3BAI1-associated protein 3. (1140 aa)
SybuSyntabulin. (523 aa)
Ncoa6Nuclear receptor coactivator 6. (1843 aa)
TtnTitin. (32000 aa)
Sirt1NAD-dependent deacetylase sirtuin-1. (554 aa)
I79_007067Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1107 aa)
Rbp4Retinol-binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (338 aa)
Lrrc3Transient receptor potential cation channel subfamily M member 2. (1604 aa)
I79_006760ADP-ribosylation factor 1. (168 aa)
GlrxGlutaredoxin-1. (106 aa)
I79_006180Neuroendocrine convertase 1; Belongs to the peptidase S8 family. (627 aa)
Igf1Insulin-like growth factor I. (75 aa)
Sytl4Synaptotagmin-like protein 4. (150 aa)
I79_005742Synaptotagmin-like protein 4. (474 aa)
FgbFibrinogen beta chain. (407 aa)
FgaFibrinogen alpha chain. (1209 aa)
Capn10Calpain-10; Belongs to the peptidase C2 family. (722 aa)
Ankrd1Ankyrin repeat domain-containing protein 1. (319 aa)
I79_004874Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (778 aa)
F2rl1Proteinase-activated receptor 2. (374 aa)
I79_004626Dynein light chain. (54 aa)
Golph3lGolgi phosphoprotein 3-like. (285 aa)
Sec24aProtein transport protein Sec24A. (837 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (222 aa)
I79_004285p2X purinoceptor 7. (805 aa)
I79_004035Disintegrin and metalloproteinase domain-containing protein 9. (1196 aa)
BlkTyrosine-protein kinase. (500 aa)
Slc30a8Zinc transporter 8. (285 aa)
Pfkfb26-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2. (784 aa)
Myh10Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1976 aa)
I79_000010Protein kinase C. (566 aa)
Ucn3Urocortin-3. (162 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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