STRINGSTRING
Il22ra2 Il22ra2 Tnfaip3 Tnfaip3 I79_001429 I79_001429 Tnfrsf1a Tnfrsf1a I79_024593 I79_024593 Tnfrsf1b Tnfrsf1b Serpinf1 Serpinf1 I79_023695 I79_023695 Rora Rora Ppara Ppara I79_022390 I79_022390 Lrfn5 Lrfn5 Alox5 Alox5 Tnfaip6 Tnfaip6 I79_020667 I79_020667 Nlrx1 Nlrx1 Socs5 Socs5 Mylk3 Mylk3 Apoa1 Apoa1 Gpr17 Gpr17 Npy5r Npy5r Nr1d1 Nr1d1 Adcyap1 Adcyap1 I79_018194 I79_018194 C1qtnf12 C1qtnf12 I79_016800 I79_016800 H671_7g18521 H671_7g18521 LDLR LDLR I79_026091 I79_026091 I79_025745 I79_025745 I79_025690 I79_025690 Nfkb1 Nfkb1 I79_025482 I79_025482 I79_025295 I79_025295 I79_025170 I79_025170 Nlrc3 Nlrc3 Adipoq Adipoq Nlrp6 Nlrp6 Adora2a Adora2a I79_015366 I79_015366 I79_015056 I79_015056 I79_015046 I79_015046 I79_015010 I79_015010 PPARG PPARG Gper1 Gper1 Pla2g5 Pla2g5 IL2 IL2 Abr Abr Psma1 Psma1 Ppard Ppard I79_013440 I79_013440 Git1 Git1 Rb1 Rb1 Ier3 Ier3 Macir Macir I79_012868 I79_012868 Hgf Hgf Apoe Apoe Pbk Pbk Foxp3 Foxp3 Bcr Bcr Ada Ada Grn Grn I79_011219 I79_011219 C1qtnf3 C1qtnf3 Gpr31 Gpr31 Zfp36 Zfp36 Cx3cl1 Cx3cl1 Mvk Mvk Acod1 Acod1 I79_010073 I79_010073 Syt11 Syt11 Ptgis Ptgis Cd276 Cd276 IL12B IL12B I79_008148 I79_008148 I79_007986 I79_007986 Ash1l Ash1l Il10 Il10 Otulin Otulin I79_007339 I79_007339 I79_006981 I79_006981 Smad3 Smad3 Gpx1 Gpx1 Ets1 Ets1 Ghsr Ghsr Acp5 Acp5 Igf1 Igf1 Cdh5 Cdh5 Nod2 Nod2 I79_005603 I79_005603 Uaca Uaca Adora1 Adora1 Socs3 Socs3 Psmb4 Psmb4 Tnfaip8l2 Tnfaip8l2 Npy Npy Isl1 Isl1 I79_004199 I79_004199 Nr1d2 Nr1d2 Tyro3 Tyro3 Mfhas1 Mfhas1 Nr1h3 Nr1h3 Mdk Mdk Nt5e Nt5e I79_000272 I79_000272 Foxf1 Foxf1 Dusp10 Dusp10 Gata3 Gata3 Gps2 Gps2 Ghrl Ghrl Pla2g10 Pla2g10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Il22ra2Interleukin-22 receptor subunit alpha-2. (239 aa)
Tnfaip3Tumor necrosis factor, alpha-induced protein 3. (776 aa)
I79_001429Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (500 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
I79_024593Uncharacterized protein. (194 aa)
Tnfrsf1bTumor necrosis factor receptor superfamily member 1B. (477 aa)
Serpinf1Pigment epithelium-derived factor; Belongs to the serpin family. (94 aa)
I79_023695Malignant fibrous histiocytoma-amplified sequence 1-like. (200 aa)
RoraNuclear receptor ROR-alpha. (959 aa)
PparaPeroxisome proliferator-activated receptor alpha. (393 aa)
I79_022390Peroxisome proliferator-activated receptor alpha. (110 aa)
Lrfn5Leucine-rich repeat and fibronectin type-III domain-containing protein 5. (770 aa)
Alox5Arachidonate 5-lipoxygenase. (674 aa)
Tnfaip6Tumor necrosis factor-inducible gene 6 protein. (275 aa)
I79_020667Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (256 aa)
Nlrx1NLR family member X1. (2478 aa)
Socs5Suppressor of cytokine signaling 5. (530 aa)
Mylk3Vacuolar protein sorting-associated protein 35. (1427 aa)
Apoa1Apolipoprotein A-I. (264 aa)
Gpr17Uracil nucleotide/cysteinyl leukotriene receptor; Belongs to the G-protein coupled receptor 1 family. (339 aa)
Npy5rNeuropeptide Y receptor type 5-like protein. (466 aa)
Nr1d1Nuclear receptor subfamily 1 group D member 1. (508 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide-like protein. (176 aa)
I79_018194Protein FAM132A. (127 aa)
C1qtnf12Protein FAM132A. (61 aa)
I79_016800Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (436 aa)
H671_7g18521Pyrin-like protein. (685 aa)
LDLRLow-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
I79_026091Pigment epithelium-derived factor; Belongs to the serpin family. (58 aa)
I79_025745Nuclear receptor subfamily 1 group D member 1. (226 aa)
I79_025690Malignant fibrous histiocytoma-amplified sequence 1. (391 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit. (509 aa)
I79_025482Nuclear factor NF-kappa-B p105 subunit. (144 aa)
I79_025295NACHT, LRR and PYD domains-containing protein 12. (91 aa)
I79_025170Slit-like 2 protein. (345 aa)
Nlrc3Protein NLRC3. (975 aa)
AdipoqAdiponectin. (248 aa)
Nlrp6NACHT, LRR and PYD domains-containing protein 6. (995 aa)
Adora2aAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
I79_015366Sharpin. (377 aa)
I79_015056Neuronal acetylcholine receptor subunit alpha-7. (412 aa)
I79_015046Low-density lipoprotein receptor. (160 aa)
I79_015010Putative E3 ubiquitin-protein ligase makorin-2. (377 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
Gper1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa)
Pla2g5Phospholipase A(2). (137 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
AbrActive breakpoint cluster region-related protein. (769 aa)
Psma1Proteasome subunit alpha type. (263 aa)
PpardPeroxisome proliferator-activated receptor delta. (440 aa)
I79_013440Calcitonin gene-related peptide type 1 receptor. (426 aa)
Git1ARF GTPase-activating protein GIT1. (809 aa)
Rb1Retinoblastoma-associated protein. (302 aa)
Ier3Radiation-inducible immediate-early gene IEX-1. (160 aa)
MacirUPF0684 protein C5orf30-like. (207 aa)
I79_012868Acyloxyacyl hydrolase. (185 aa)
HgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
ApoeApolipoprotein E. (313 aa)
PbkLymphokine-activated killer T-cell-originated protein kinase. (323 aa)
Foxp3Forkhead box protein P3. (428 aa)
BcrBreakpoint cluster region protein. (1193 aa)
AdaAdenosine deaminase. (363 aa)
GrnGranulins. (592 aa)
I79_011219Vitamin K-dependent protein C. (381 aa)
C1qtnf3Complement C1q tumor necrosis factor-related protein 3. (319 aa)
Gpr31Putative G-protein coupled receptor 31; Belongs to the G-protein coupled receptor 1 family. (319 aa)
Zfp36Tristetraproline. (315 aa)
Cx3cl1Fractalkine. (335 aa)
MvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (389 aa)
Acod1Immune-responsive gene 1 protein. (290 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
Syt11Synaptotagmin-11. (111 aa)
PtgisProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (501 aa)
Cd276CD276 antigen. (316 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
I79_008148Glutathione peroxidase 2. (151 aa)
I79_007986Putative histone-lysine N-methyltransferase ASH1L. (455 aa)
Ash1lPutative histone-lysine N-methyltransferase ASH1L. (1546 aa)
Il10Interleukin-10. (178 aa)
OtulinProtein FAM105B. (298 aa)
I79_007339Protein NOV-like. (256 aa)
I79_006981G-protein coupled receptor 120. (318 aa)
Smad3Mothers against decapentaplegic homolog. (363 aa)
Gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
Ets1Protein C-ets-1. (257 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Acp5Tartrate-resistant acid phosphatase type 5. (330 aa)
Igf1Insulin-like growth factor I. (75 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (763 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2. (989 aa)
I79_005603Putative ubiquitin carboxyl-terminal hydrolase CYLD. (730 aa)
UacaUveal autoantigen with coiled-coil domains and ankyrin repeats. (1396 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
Socs3Suppressor of cytokine signaling 3. (225 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Tnfaip8l2Tumor necrosis factor, alpha-induced protein 8-like protein 2. (184 aa)
NpyNeuropeptide Y. (148 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
I79_004199Acid sphingomyelinase-like phosphodiesterase 3b. (392 aa)
Nr1d2Nuclear receptor subfamily 1 group D member 2. (265 aa)
Tyro3Tyrosine-protein kinase receptor TYRO3. (816 aa)
Mfhas1Malignant fibrous histiocytoma-amplified sequence 1-like. (1025 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
MdkMidkine. (160 aa)
Nt5e5'-nucleotidase; Belongs to the 5'-nucleotidase family. (556 aa)
I79_000272WAP four-disulfide core domain protein 1. (275 aa)
Foxf1Forkhead box protein F1. (320 aa)
Dusp10Dual specificity protein phosphatase 10. (482 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3. (443 aa)
Gps2G protein pathway suppressor 2. (327 aa)
GhrlAppetite-regulating hormone. (100 aa)
Pla2g10Phospholipase A(2). (140 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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