STRINGSTRING
I79_004031 I79_004031 I79_005449 I79_005449 I79_005944 I79_005944 Il1rl1 Il1rl1 Lpl Lpl Ets1 Ets1 Il17ra Il17ra Hyal2 Hyal2 Ednra Ednra Zp3 Zp3 Serpine1 Serpine1 I79_007297 I79_007297 I79_007841 I79_007841 C3 C3 Cd47 Cd47 I79_008639 I79_008639 I79_008640 I79_008640 I79_008941 I79_008941 C2cd4c C2cd4c Abcc1 Abcc1 Ido1 Ido1 Tnfsf11 Tnfsf11 I79_010073 I79_010073 Trpv4 Trpv4 Cx3cl1 Cx3cl1 I79_010620 I79_010620 Hspd1 Hspd1 Grn Grn I79_011711 I79_011711 I79_011712 I79_011712 Aoc3 Aoc3 Ifi35 Ifi35 App App Ninj1 Ninj1 Vamp8 Vamp8 Nfkbiz Nfkbiz Vamp7 Vamp7 I79_015046 I79_015046 I79_015109 I79_015109 CgPICR_014700 CgPICR_014700 I79_015458 I79_015458 Cd81 Cd81 CgPICR_015958 CgPICR_015958 I79_016228 I79_016228 Napepld Napepld Ager Ager I79_016423 I79_016423 Tnf Tnf Lta Lta Tradd Tradd Pde2a Pde2a H671_7g18521 H671_7g18521 I79_016754 I79_016754 Osm Osm Tlr4 Tlr4 IL1B IL1B H671_3g9603 H671_3g9603 Pla2g3 Pla2g3 Nfkbia Nfkbia Fabp4 Fabp4 Kars1 Kars1 Il33 Il33 Lgals2 Lgals2 Lgals1 Lgals1 Ccr7 Ccr7 Nlrp10 Nlrp10 CgPICR_003405 CgPICR_003405 I79_019042 I79_019042 Npy5r Npy5r Pdcd4 Pdcd4 I79_019425 I79_019425 Ctsc Ctsc Ccdc142 Ccdc142 I79_019770 I79_019770 Ccl5 Ccl5 I79_020009 I79_020009 H671_5g14804 H671_5g14804 Sucnr1 Sucnr1 Adam8 Adam8 IL16 IL16 I79_021835 I79_021835 I79_021836 I79_021836 I79_021837 I79_021837 Ripk1 Ripk1 Jak2 Jak2 Park7 Park7 I79_022300 I79_022300 Setd4 Setd4 Nppa Nppa Tlr3 Tlr3 I79_024147 I79_024147 I79_024210 I79_024210 I79_024407 I79_024407 Nmi Nmi Nlrp6 Nlrp6 I79_025549 I79_025549 I79_025994 I79_025994 LDLR LDLR Plcg2 Plcg2 I79_000677 I79_000677 Ccl1 Ccl1 Tnfrsf1a Tnfrsf1a Wnt5a Wnt5a I79_001465 I79_001465 Alox5ap Alox5ap Pla2g4a Pla2g4a Ptgs2 Ptgs2 Cdk19 Cdk19 I79_002817 I79_002817 I79_002818 I79_002818 I79_002819 I79_002819 I79_002821 I79_002821 Mdk Mdk Cd28 Cd28 Tlr9 Tlr9 Tnfsf4 Tnfsf4 I79_003972 I79_003972 Il18 Il18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_004031Fibroblast growth factor receptor. (731 aa)
I79_005449TNFAIP3-interacting protein 1. (623 aa)
I79_005944Interleukin-1 receptor-like 1. (218 aa)
Il1rl1Interleukin-1 receptor-like 1. (331 aa)
LplLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (450 aa)
Ets1Protein C-ets-1. (257 aa)
Il17raInterleukin-17 receptor A. (865 aa)
Hyal2Hyaluronidase. (359 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
Zp3Zona pellucida sperm-binding protein 3. (403 aa)
Serpine1Plasminogen activator inhibitor 1; Belongs to the serpin family. (270 aa)
I79_007297Plasminogen activator inhibitor 1; Belongs to the serpin family. (108 aa)
I79_007841Z-DNA-binding protein 1. (235 aa)
C3Complement C3. (1626 aa)
Cd47Leukocyte surface antigen CD47. (268 aa)
I79_008639NF-kappa-B inhibitor alpha. (52 aa)
I79_008640NF-kappa-B inhibitor alpha. (90 aa)
I79_008941Receptor protein-tyrosine kinase. (962 aa)
C2cd4cNuclear-localized factor 3. (509 aa)
Abcc1Multidrug resistance-associated protein 1. (146 aa)
Ido1Indoleamine 2,3-dioxygenase 1. (567 aa)
Tnfsf11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (199 aa)
I79_010073Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (511 aa)
Trpv4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
Cx3cl1Fractalkine. (335 aa)
I79_010620Alpha-synuclein; Belongs to the synuclein family. (166 aa)
Hspd160 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (526 aa)
GrnGranulins. (592 aa)
I79_011711Signal transducer and activator of transcription 5B. (274 aa)
I79_011712Signal transducer and activator of transcription. (793 aa)
Aoc3Amine oxidase. (763 aa)
Ifi35Interferon-induced 35 kDa protein-like. (286 aa)
AppAmyloid beta A4 protein. (433 aa)
Ninj1Ninjurin-1. (102 aa)
Vamp8Vesicle-associated membrane protein 8. (101 aa)
NfkbizNF-kappa-B inhibitor zeta. (410 aa)
Vamp7Vesicle-associated membrane protein 7-like isoform 1; Belongs to the synaptobrevin family. (220 aa)
I79_015046Low-density lipoprotein receptor. (160 aa)
I79_015109Interleukin-6. (174 aa)
CgPICR_014700C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
I79_015458C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (337 aa)
Cd81Tetraspanin. (236 aa)
CgPICR_015958D-dopachrome decarboxylase. (118 aa)
I79_016228Tau-tubulin kinase 1. (1400 aa)
NapepldN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D. (236 aa)
AgerAdvanced glycosylation end product-specific receptor. (334 aa)
I79_016423Advanced glycosylation end product-specific receptor. (65 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
LtaLymphotoxin-alpha; Belongs to the tumor necrosis factor family. (202 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein. (306 aa)
Pde2acGMP-dependent 3',5'-cyclic phosphodiesterase; Belongs to the cyclic nucleotide phosphodiesterase family. (216 aa)
H671_7g18521Pyrin-like protein. (685 aa)
I79_016754NACHT, LRR and PYD domains-containing protein 1. (382 aa)
OsmOncostatin-M. (222 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
H671_3g960360 kDa heat shock protein, mitochondrial. (141 aa)
Pla2g3Group 3 secretory phospholipase A2. (398 aa)
NfkbiaNF-kappa-B inhibitor alpha. (224 aa)
Fabp4Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
Kars1Lysine--tRNA ligase. (626 aa)
Il33Interleukin-33. (217 aa)
Lgals2Galectin. (174 aa)
Lgals1Galectin. (135 aa)
Ccr7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
Nlrp10NACHT, LRR and PYD domains-containing protein 10. (675 aa)
CgPICR_003405C-C motif chemokine. (98 aa)
I79_01904260 kDa heat shock protein, mitochondrial. (169 aa)
Npy5rNeuropeptide Y receptor type 5-like protein. (466 aa)
Pdcd4Programmed cell death protein 4. (469 aa)
I79_019425Apoptosis-associated speck-like protein containing a CARD. (192 aa)
CtscDipeptidyl-peptidase 1; Belongs to the peptidase C1 family. (483 aa)
Ccdc142Coiled-coil domain-containing protein 142. (723 aa)
I79_019770Protein S100; Belongs to the S-100 family. (124 aa)
Ccl5C-C motif chemokine. (91 aa)
I79_020009Phosphodiesterase. (597 aa)
H671_5g14804Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1012 aa)
Sucnr1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (244 aa)
Adam8Disintegrin and metalloproteinase domain-containing protein 8. (936 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1017 aa)
I79_021835Leucine-rich repeat serine/threonine-protein kinase 2. (354 aa)
I79_021836Leucine-rich repeat serine/threonine-protein kinase 2. (1184 aa)
I79_021837Leucine-rich repeat serine/threonine-protein kinase 2. (441 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (655 aa)
Jak2Tyrosine-protein kinase. (1122 aa)
Park7Protein DJ-1. (189 aa)
I79_02230060 kDa heat shock protein, mitochondrial. (252 aa)
Setd4SET domain-containing protein 4. (123 aa)
NppaAtrial natriuretic factor. (362 aa)
Tlr3Toll-like receptor 3. (164 aa)
I79_024147Adenosine A3 receptor; Belongs to the G-protein coupled receptor 1 family. (275 aa)
I79_024210Nuclear protein 1. (103 aa)
I79_02440760 kDa heat shock protein, mitochondrial. (214 aa)
NmiN-myc-interactor. (303 aa)
Nlrp6NACHT, LRR and PYD domains-containing protein 6. (995 aa)
I79_025549WNT1-inducible-signaling pathway protein 1. (274 aa)
I79_025994WNT1-inducible-signaling pathway protein 1. (136 aa)
LDLRLow-density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family. (862 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
I79_000677Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (415 aa)
Ccl1C-C motif chemokine 1. (91 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (355 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
I79_001465Interleukin-17 receptor B. (409 aa)
Alox5apArachidonate 5-lipoxygenase-activating protein. (161 aa)
Pla2g4aPhospholipase A2. (749 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Cdk19Cell division cycle 2-like protein kinase 6. (404 aa)
I79_002817NACHT, LRR and PYD domains-containing protein 1. (1176 aa)
I79_002818NACHT, LRR and PYD domains-containing protein 1. (1063 aa)
I79_002819NACHT, LRR and PYD domains-containing protein 1. (866 aa)
I79_002821NACHT, LRR and PYD domains-containing protein 1. (422 aa)
MdkMidkine. (160 aa)
Cd28T-cell-specific surface glycoprotein CD28. (100 aa)
Tlr9Toll-like receptor 9. (1239 aa)
Tnfsf4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (185 aa)
I79_00397260 kDa heat shock protein, mitochondrial; Belongs to the TCP-1 chaperonin family. (104 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (196 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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