(40 nodes) Positive regulation of calcium-mediated signaling network (Cricetulus griseus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cib1	Calcium and integrin-binding protein 1. (191 aa)
	Plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
	Cdh13	Cadherin-13. (377 aa)
	I79_000473	Transmembrane protein 110. (204 aa)
	I79_000474	Transmembrane protein 110. (86 aa)
	Cd4	T-cell surface glycoprotein CD4. (447 aa)
	Lmcd1	LIM and cysteine-rich domains protein 1. (332 aa)
	Hint1	Histidine triad nucleotide-binding protein 1. (97 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (688 aa)
	I79_005719	Neurogenic differentiation factor 2. (352 aa)
	Igf1	Insulin-like growth factor I. (75 aa)
	I79_006472	Polypyrimidine tract-binding protein 1. (119 aa)
	Ptbp1	Polypyrimidine tract-binding protein 1. (528 aa)
	Exoc4	Exocyst complex component 4. (508 aa)
	I79_009921	Exocyst complex component 4. (445 aa)
	Sppl3	Signal peptide peptidase-like 3. (347 aa)
	Syk	Tyrosine-protein kinase. (611 aa)
	Cd8a	T-cell surface glycoprotein CD8 alpha chain. (144 aa)
	Ada	Adenosine deaminase. (363 aa)
	Ikzf4	Receptor protein-tyrosine kinase. (1902 aa)
	L1cam	Neural cell adhesion molecule L1. (1287 aa)
	I79_014451	Pro-neuregulin-1, membrane-bound isoform. (639 aa)
	Slc9a1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (821 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	CgPICR_003405	C-C motif chemokine. (98 aa)
	I79_005170	Uncharacterized protein. (92 aa)
	CgPICR_014162	Polypyrimidine tract-binding protein 1. (575 aa)
	Akap6	A-kinase anchor protein 6. (1368 aa)
	I79_022034	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1150 aa)
	I79_023431	Polypyrimidine tract-binding protein 1. (323 aa)
	Cherp	Calcium homeostasis endoplasmic reticulum protein. (125 aa)
	I79_024079	Calmodulin-binding transcription activator 1. (402 aa)
	I79_024147	Adenosine A3 receptor; Belongs to the G-protein coupled receptor 1 family. (275 aa)
	I79_024241	Calmodulin-binding transcription activator 1. (877 aa)
	I79_024406	A-kinase anchor protein 6. (211 aa)
	Itgal	Integrin alpha-L; Belongs to the integrin alpha chain family. (699 aa)
	Chp2	Calcineurin B-likeous protein 2. (196 aa)
	I79_025274	Integrin alpha-L. (331 aa)
	I79_004399	Neural cell adhesion molecule 1. (1071 aa)
	I79_004087	Tyrosine-protein kinase. (593 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ada	Cd4	G3HLR7	G3GUN9	Adenosine deaminase.	T-cell surface glycoprotein CD4.	0.527
Akap6	I79_024406	G3IAI2	G3IKK3	A-kinase anchor protein 6.	A-kinase anchor protein 6.	0.921
Cd4	Ada	G3GUN9	G3HLR7	T-cell surface glycoprotein CD4.	Adenosine deaminase.	0.527
Cd4	Cd8a	G3GUN9	G3HJJ9	T-cell surface glycoprotein CD4.	T-cell surface glycoprotein CD8 alpha chain.	0.981
Cd4	CgPICR_003405	G3GUN9	G3I640	T-cell surface glycoprotein CD4.	C-C motif chemokine.	0.617
Cd4	I79_004087	G3GUN9	G3H1Q5	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.743
Cd4	I79_004399	G3GUN9	G3H2I6	T-cell surface glycoprotein CD4.	Neural cell adhesion molecule 1.	0.410
Cd4	I79_025274	G3GUN9	G3IMX0	T-cell surface glycoprotein CD4.	Integrin alpha-L.	0.421
Cd4	Igf1	G3GUN9	G3H672	T-cell surface glycoprotein CD4.	Insulin-like growth factor I.	0.589
Cd4	Itgal	G3GUN9	G3IKR2	T-cell surface glycoprotein CD4.	Integrin alpha-L; Belongs to the integrin alpha chain family.	0.421
Cd4	Syk	G3GUN9	G3HIA4	T-cell surface glycoprotein CD4.	Tyrosine-protein kinase.	0.754
Cd4	Tnf	G3GUN9	G3HZG9	T-cell surface glycoprotein CD4.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.884
Cd8a	Cd4	G3HJJ9	G3GUN9	T-cell surface glycoprotein CD8 alpha chain.	T-cell surface glycoprotein CD4.	0.981
Cd8a	I79_004087	G3HJJ9	G3H1Q5	T-cell surface glycoprotein CD8 alpha chain.	Tyrosine-protein kinase.	0.653
Cd8a	I79_004399	G3HJJ9	G3H2I6	T-cell surface glycoprotein CD8 alpha chain.	Neural cell adhesion molecule 1.	0.570
Cd8a	Syk	G3HJJ9	G3HIA4	T-cell surface glycoprotein CD8 alpha chain.	Tyrosine-protein kinase.	0.434
Cd8a	Tnf	G3HJJ9	G3HZG9	T-cell surface glycoprotein CD8 alpha chain.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.695
CgPICR_003405	Cd4	G3I640	G3GUN9	C-C motif chemokine.	T-cell surface glycoprotein CD4.	0.617
CgPICR_003405	Tnf	G3I640	G3HZG9	C-C motif chemokine.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.771
Chp2	Slc9a1	G3ILP8	G3HYP1	Calcineurin B-likeous protein 2.	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	0.907