(43 nodes) Regulation of antigen receptor-mediated signaling pathway network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	Slc39a10	Zinc transporter ZIP10. (791 aa)
	Elf1	ETS-related transcription factor Elf-1. (616 aa)
	Phpt1	14 kDa phosphohistidine phosphatase. (124 aa)
	Prkch	Protein kinase C eta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (635 aa)
	Thy1	Thy-1 membrane glycoprotein. (147 aa)
	I79_023721	Leupaxin. (365 aa)
	I79_024695	Butyrophilin-like protein 2. (415 aa)
	Bcl10	B-cell lymphoma/leukemia 10. (232 aa)
	I79_016311	PRKC apoptosis WT1 regulator protein. (214 aa)
	Nfam1	NFAT activation molecule 1. (175 aa)
	Tespa1	Uncharacterized protein KIAA0748-like. (496 aa)
	Lyn	Tyrosine-protein kinase. (289 aa)
	I79_017561	Tyrosine-protein kinase Lyn. (101 aa)
	Ccr7	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	I79_018849	Serine/threonine-protein kinase D2. (513 aa)
	Kcnn4	Intermediate conductance calcium-activated potassium channel protein 4. (54 aa)
	CgPICR_011244	40S ribosomal protein S3. (94 aa)
	Rps3	40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (117 aa)
	Rela	Transcription factor p65. (546 aa)
	Cd81	Tetraspanin. (236 aa)
	Ezr	Ezrin. (586 aa)
	Cblb	E3 ubiquitin-protein ligase CBL-B. (984 aa)
	I79_012810	B-cell receptor CD22. (504 aa)
	I79_012384	Leukocyte common antigen. (962 aa)
	Ada	Adenosine deaminase. (363 aa)
	Ubash3a	Ubiquitin-associated and SH3 domain-containing protein A. (624 aa)
	Lck	Proto-oncogene tyrosine-protein kinase LCK. (158 aa)
	Lgals3	Galectin. (281 aa)
	Cmtm3	CKLF-like MARVEL transmembrane domain-containing protein 3. (184 aa)
	I79_005603	Putative ubiquitin carboxyl-terminal hydrolase CYLD. (730 aa)
	Prnp	Major prion protein; Belongs to the prion family. (254 aa)
	I79_004486	CD160 antigen. (151 aa)
	Laptm5	Lysosomal-associated transmembrane protein 5. (232 aa)
	Blk	Tyrosine-protein kinase. (500 aa)
	Serpinc1	Roquin; Belongs to the serpin family. (1418 aa)
	Ptprj	Receptor-type tyrosine-protein phosphatase eta. (1077 aa)
	Dgkz	Diacylglycerol kinase zeta. (112 aa)
	Gps2	G protein pathway suppressor 2. (327 aa)
	Dusp22	Dual specificity protein phosphatase 22. (197 aa)
	I79_001680	Caspase recruitment domain-containing protein 11. (1089 aa)
	Ptpn6	Tyrosine-protein phosphatase non-receptor type 6. (592 aa)
	I79_000959	CMRF35-like molecule 8. (295 aa)
	Foxp1	Forkhead box protein P1. (696 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bcl10	I79_001680	G3IMU1	G3GVE3	B-cell lymphoma/leukemia 10.	Caspase recruitment domain-containing protein 11.	0.968
Bcl10	Prkch	G3IMU1	G3HZ02	B-cell lymphoma/leukemia 10.	Protein kinase C eta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.424
Bcl10	Rela	G3IMU1	G3IDM9	B-cell lymphoma/leukemia 10.	Transcription factor p65.	0.575
Blk	Cblb	G3H0L5	G3HRG2	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL-B.	0.529
Blk	I79_012384	G3H0L5	G3HNP2	Tyrosine-protein kinase.	Leukocyte common antigen.	0.436
Blk	I79_012810	G3H0L5	G3HPU0	Tyrosine-protein kinase.	B-cell receptor CD22.	0.560
Blk	I79_023721	G3H0L5	G3IIP8	Tyrosine-protein kinase.	Leupaxin.	0.408
Blk	Ptpn6	G3H0L5	G3GUQ5	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type 6.	0.413
Cblb	Blk	G3HRG2	G3H0L5	E3 ubiquitin-protein ligase CBL-B.	Tyrosine-protein kinase.	0.529
Cblb	I79_017561	G3HRG2	G3I2D2	E3 ubiquitin-protein ligase CBL-B.	Tyrosine-protein kinase Lyn.	0.786
Cblb	Lck	G3HRG2	G3H943	E3 ubiquitin-protein ligase CBL-B.	Proto-oncogene tyrosine-protein kinase LCK.	0.967
Cblb	Lyn	G3HRG2	G3I2D1	E3 ubiquitin-protein ligase CBL-B.	Tyrosine-protein kinase.	0.786
Cblb	Ptpn6	G3HRG2	G3GUQ5	E3 ubiquitin-protein ligase CBL-B.	Tyrosine-protein phosphatase non-receptor type 6.	0.644
Cblb	Ubash3a	G3HRG2	G3HLD8	E3 ubiquitin-protein ligase CBL-B.	Ubiquitin-associated and SH3 domain-containing protein A.	0.626
Ccr7	I79_012384	G3I5N8	G3HNP2	C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family.	Leukocyte common antigen.	0.553
Cd81	I79_012810	G3HXZ3	G3HPU0	Tetraspanin.	B-cell receptor CD22.	0.537
CgPICR_011244	Rela	G3I607	G3IDM9	40S ribosomal protein S3.	Transcription factor p65.	0.573
I79_001680	Bcl10	G3GVE3	G3IMU1	Caspase recruitment domain-containing protein 11.	B-cell lymphoma/leukemia 10.	0.968
I79_001680	Prkch	G3GVE3	G3HZ02	Caspase recruitment domain-containing protein 11.	Protein kinase C eta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.609
I79_001680	Rela	G3GVE3	G3IDM9	Caspase recruitment domain-containing protein 11.	Transcription factor p65.	0.485