(35 nodes) Positive chemotaxis network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Sema5a	Semaphorin-5A. (1046 aa)
	Colec10	Collectin-10. (277 aa)
	I79_007063	Hepatocyte growth factor receptor. (1222 aa)
	I79_007548	Angiopoietin-1. (112 aa)
	Tsc2	Tuberin. (1546 aa)
	Pgf	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (154 aa)
	Vegfc	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
	I79_009992	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (259 aa)
	Cx3cl1	Fractalkine. (335 aa)
	I79_010622	Leucine-rich repeat-containing protein 1. (119 aa)
	Lrrc1	Leucine-rich repeat-containing protein 1. (167 aa)
	Hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
	I79_013970	Plexin-B3. (1806 aa)
	Lrp1	Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
	I79_015381	Protein scribble-like. (789 aa)
	Npm3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
	Nrp1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	Pdgfb	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (205 aa)
	I79_018349	Coronin-1A. (143 aa)
	CgPICR_003405	C-C motif chemokine. (98 aa)
	I79_019149	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
	Vegfb	Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (150 aa)
	I79_019773	Protein S100-A15A. (108 aa)
	Ccl5	C-C motif chemokine. (91 aa)
	Fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	I79_021283	Angiopoietin-1. (298 aa)
	Wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	Scg2	Secretogranin-2. (763 aa)
	I79_001239	Low-density lipoprotein receptor-related protein 2. (4664 aa)
	Ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (258 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	Ptprj	Receptor-type tyrosine-protein phosphatase eta. (1077 aa)
	Alkbh1	Alkylated DNA repair protein alkB-like 1. (258 aa)
	Lgals3	Galectin. (281 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccl5	CgPICR_003405	G3I8B1	G3I640	C-C motif chemokine.	C-C motif chemokine.	0.961
Ccl5	Cx3cl1	G3I8B1	G3HIL2	C-C motif chemokine.	Fractalkine.	0.792
Ccl5	Lgals3	G3I8B1	G3H7B3	C-C motif chemokine.	Galectin.	0.566
CgPICR_003405	Ccl5	G3I640	G3I8B1	C-C motif chemokine.	C-C motif chemokine.	0.961
CgPICR_003405	Cx3cl1	G3I640	G3HIL2	C-C motif chemokine.	Fractalkine.	0.598
Cx3cl1	Ccl5	G3HIL2	G3I8B1	Fractalkine.	C-C motif chemokine.	0.792
Cx3cl1	CgPICR_003405	G3HIL2	G3I640	Fractalkine.	C-C motif chemokine.	0.598
Fgf7	Hgf	G3IAS3	G3HPQ5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.786
Fgf7	I79_006254	G3IAS3	G3H7C4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.528
Fgf7	I79_007063	G3IAS3	G3H9I9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hepatocyte growth factor receptor.	0.416
Fgf7	I79_007548	G3IAS3	G3HAT9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Angiopoietin-1.	0.538
Fgf7	I79_021283	G3IAS3	G3IC93	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Angiopoietin-1.	0.538
Fgf7	Nrp1	G3IAS3	G3HZ57	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neuropilin; Belongs to the neuropilin family.	0.734
Fgf7	Pdgfb	G3IAS3	G3I2J0	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.495
Fgf7	Pgf	G3IAS3	G3HFQ6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.405
Fgf7	Wnt5a	G3IAS3	G3GUT6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
Hgf	Fgf7	G3HPQ5	G3IAS3	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.786
Hgf	I79_007063	G3HPQ5	G3H9I9	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor receptor.	0.990
Hgf	I79_007548	G3HPQ5	G3HAT9	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Angiopoietin-1.	0.473
Hgf	I79_013970	G3HPQ5	G3HSX1	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Plexin-B3.	0.400