(56 nodes) Negative regulation of chemotaxis network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_016800	Cytochrome P450 19A1; Belongs to the cytochrome P450 family. (436 aa)
	I79_016618	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (470 aa)
	Aif1	Allograft inflammatory factor 1. (80 aa)
	I79_025170	Slit-like 2 protein. (345 aa)
	I79_024593	Uncharacterized protein. (194 aa)
	Sema4g	Semaphorin-4G; Belongs to the semaphorin family. (757 aa)
	Nrp1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	Sema4b	Semaphorin-4B; Belongs to the semaphorin family. (792 aa)
	I79_023328	Complement C5. (498 aa)
	Padi2	Protein-arginine deiminase type-2. (650 aa)
	Tnfaip6	Tumor necrosis factor-inducible gene 6 protein. (275 aa)
	Grem1	Gremlin-1. (117 aa)
	I79_021038	Plexin-A3. (334 aa)
	Plxna3	Plexin-A3. (656 aa)
	I79_000669	Semaphorin-5B. (979 aa)
	CgPICR_003438	C-C motif chemokine. (143 aa)
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	I79_003408	Slit-like 1 protein. (1482 aa)
	Sema4c	Semaphorin-4C; Belongs to the semaphorin family. (834 aa)
	Sema6c	Semaphorin-6C; Belongs to the semaphorin family. (331 aa)
	Sema5a	Semaphorin-5A. (1046 aa)
	Sema3b	Semaphorin-3B; Belongs to the semaphorin family. (749 aa)
	Sema3f	Semaphorin-3F; Belongs to the semaphorin family. (785 aa)
	Dusp1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	I79_007339	Protein NOV-like. (256 aa)
	I79_007709	SCO-spondin. (353 aa)
	I79_007744	Angiopoietin-2. (188 aa)
	Angpt2	Angiopoietin-2. (288 aa)
	Sema6b	Semaphorin-6B; Belongs to the semaphorin family. (823 aa)
	I79_008405	Tyrosine-protein kinase RYK. (141 aa)
	Sema7a	Semaphorin-7A; Belongs to the semaphorin family. (560 aa)
	Sema4a	Semaphorin-4A; Belongs to the semaphorin family. (761 aa)
	Gpr18	N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (331 aa)
	I79_010136	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (230 aa)
	Robo1	Roundabout-like 1. (129 aa)
	I79_010159	Roundabout-like 1. (1362 aa)
	Thbs1	Thrombospondin-1. (533 aa)
	H671_3g8622	Semaphorin-4D; Belongs to the semaphorin family. (833 aa)
	I79_011934	Semaphorin-6D. (150 aa)
	I79_011935	Semaphorin-6D; Belongs to the semaphorin family. (780 aa)
	I79_011943	Semaphorin-3C. (86 aa)
	Sema3c	Semaphorin-3C; Belongs to the semaphorin family. (493 aa)
	I79_012060	Roundabout-like 2. (1397 aa)
	Sema3a	Semaphorin-3A-like protein; Belongs to the semaphorin family. (758 aa)
	Sema3e	Semaphorin-3E; Belongs to the semaphorin family. (777 aa)
	I79_012498	Semaphorin-6A. (305 aa)
	Sema6a	Semaphorin-6A; Belongs to the semaphorin family. (503 aa)
	Sema3d	Semaphorin-3D; Belongs to the semaphorin family. (759 aa)
	Nbl1	Neuroblastoma suppressor of tumorigenicity 1-like protein. (178 aa)
	St6gal1	Beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (402 aa)
	Mmp28	Matrix metalloproteinase-28. (263 aa)
	I79_019777	Matrix metalloproteinase-28. (253 aa)
	Sema4f	Semaphorin-4F; Belongs to the semaphorin family. (751 aa)
	I79_018312	Tyrosine-protein kinase RYK. (163 aa)
	Coro1b	Coronin; Belongs to the WD repeat coronin family. (484 aa)
	Rin3	Ras and Rab interactor 3. (949 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aif1	CgPICR_003438	G3HZG7	G3GTT2	Allograft inflammatory factor 1.	C-C motif chemokine.	0.406
Angpt2	I79_007744	G3HBB9	G3HBB8	Angiopoietin-2.	Angiopoietin-2.	0.764
CgPICR_003438	Aif1	G3GTT2	G3HZG7	C-C motif chemokine.	Allograft inflammatory factor 1.	0.406
CgPICR_003438	Tnfaip6	G3GTT2	G3IDR6	C-C motif chemokine.	Tumor necrosis factor-inducible gene 6 protein.	0.403
H671_3g8622	I79_021038	G3HIA8	G3IBL2	Semaphorin-4D; Belongs to the semaphorin family.	Plexin-A3.	0.565
H671_3g8622	Nrp1	G3HIA8	G3HZ57	Semaphorin-4D; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.461
H671_3g8622	Plxna3	G3HIA8	G3IBL1	Semaphorin-4D; Belongs to the semaphorin family.	Plexin-A3.	0.565
I79_000669	I79_021038	G3GSQ1	G3IBL2	Semaphorin-5B.	Plexin-A3.	0.551
I79_000669	Nrp1	G3GSQ1	G3HZ57	Semaphorin-5B.	Neuropilin; Belongs to the neuropilin family.	0.748
I79_000669	Plxna3	G3GSQ1	G3IBL1	Semaphorin-5B.	Plexin-A3.	0.551
I79_003408	I79_010159	G3GZW0	G3HHQ3	Slit-like 1 protein.	Roundabout-like 1.	0.860
I79_003408	I79_012060	G3GZW0	G3HMT6	Slit-like 1 protein.	Roundabout-like 2.	0.917
I79_003408	Robo1	G3GZW0	G3HHQ2	Slit-like 1 protein.	Roundabout-like 1.	0.860
I79_003408	Sema4f	G3GZW0	G3I7U4	Slit-like 1 protein.	Semaphorin-4F; Belongs to the semaphorin family.	0.557
I79_007709	Nrp1	G3HB88	G3HZ57	SCO-spondin.	Neuropilin; Belongs to the neuropilin family.	0.510
I79_007744	Angpt2	G3HBB8	G3HBB9	Angiopoietin-2.	Angiopoietin-2.	0.764
I79_008405	I79_010136	G3HD31	G3HHN2	Tyrosine-protein kinase RYK.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.729
I79_008405	Wnt5a	G3HD31	G3GUT6	Tyrosine-protein kinase RYK.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.773
I79_010136	I79_008405	G3HHN2	G3HD31	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Tyrosine-protein kinase RYK.	0.729
I79_010136	I79_018312	G3HHN2	G3I4D5	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Tyrosine-protein kinase RYK.	0.729