(52 nodes) Release of sequestered calcium ion into cytosol network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Xcr1	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family. (322 aa)
	I79_015458	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (337 aa)
	I79_015475	Mucolipin-1. (532 aa)
	Itpr2	Inositol 1,4,5-trisphosphate receptor type 2. (470 aa)
	Htr2c	5-hydroxytryptamine receptor 2C. (317 aa)
	I79_017637	Transient receptor potential cation channel subfamily A member 1. (291 aa)
	I79_017638	Transient receptor potential cation channel subfamily A member 1. (312 aa)
	I79_018131	5-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (237 aa)
	Htr2a	5-hydroxytryptamine receptor 2A. (264 aa)
	CgPICR_003405	C-C motif chemokine. (98 aa)
	Slc8b1	Sodium/potassium/calcium exchanger 6; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (482 aa)
	Tpcn1	Two pore calcium channel protein 1. (372 aa)
	I79_019230	Inositol 1,4,5-trisphosphate receptor type 3. (836 aa)
	Rasa3	Ras GTPase-activating protein 3. (789 aa)
	Mcoln2	Mucolipin-2. (151 aa)
	I79_020737	Platelet glycoprotein V. (355 aa)
	Mcoln3	Mucolipin-3. (553 aa)
	I79_022311	Two pore calcium channel protein 2. (227 aa)
	Tpcn2	Two pore calcium channel protein 2. (338 aa)
	I79_024483	Polycystin-2. (192 aa)
	I79_024744	5-hydroxytryptamine receptor 2B. (407 aa)
	I79_025625	Polycystin-2. (318 aa)
	Plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1199 aa)
	H671_2g5863	Trimeric intracellular cation channel type B-like protein. (176 aa)
	Gp1ba	Platelet glycoprotein Ib alpha chain. (446 aa)
	H671_5g14837	Tumor necrosis factor ligand superfamily member 6-like isoform 1; Belongs to the tumor necrosis factor family. (192 aa)
	Fkbp1b	Peptidylprolyl isomerase. (143 aa)
	I79_004285	p2X purinoceptor 7. (805 aa)
	Drd2	D(2) dopamine receptor. (274 aa)
	I79_004403	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
	F2r	Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (396 aa)
	I79_004653	Inositol 1,4,5-trisphosphate receptor type 1. (2569 aa)
	I79_005170	Uncharacterized protein. (92 aa)
	Cherp	Calcium homeostasis endoplasmic reticulum protein. (125 aa)
	Fkbp1a	Peptidylprolyl isomerase. (79 aa)
	I79_006143	Inhibitor of Bruton tyrosine kinase. (1086 aa)
	Lrrc3	Transient receptor potential cation channel subfamily M member 2. (1604 aa)
	Lck	Proto-oncogene tyrosine-protein kinase LCK. (158 aa)
	I79_008828	Lymphotactin. (114 aa)
	Gp9	Platelet glycoprotein IX. (177 aa)
	I79_010444	Ryanodine receptor 3. (85 aa)
	Ryr3	Ryanodine receptor 3. (172 aa)
	I79_010748	Ryanodine receptor 1. (1261 aa)
	I79_010749	Ryanodine receptor 1. (1965 aa)
	Letm1	LETM1 and EF-hand domain-containing protein 1, mitochondrial. (700 aa)
	Glp1r	Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (437 aa)
	Ccl21	C-C motif chemokine 21a. (148 aa)
	Ccl19	C-C motif chemokine. (117 aa)
	I79_012384	Leukocyte common antigen. (962 aa)
	I79_012424	Ryanodine receptor 2. (2535 aa)
	I79_012425	Ryanodine receptor 2. (2233 aa)
	Ddit3	DNA damage-inducible transcript 3. (167 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccl19	Ccl21	G3HN20	G3HN19	C-C motif chemokine.	C-C motif chemokine 21a.	0.990
Ccl19	CgPICR_003405	G3HN20	G3I640	C-C motif chemokine.	C-C motif chemokine.	0.571
Ccl19	I79_012384	G3HN20	G3HNP2	C-C motif chemokine.	Leukocyte common antigen.	0.455
Ccl19	I79_015458	G3HN20	G3HWU5	C-C motif chemokine.	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.879
Ccl19	Xcr1	G3HN20	G3HWT9	C-C motif chemokine.	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.714
Ccl21	Ccl19	G3HN19	G3HN20	C-C motif chemokine 21a.	C-C motif chemokine.	0.990
Ccl21	I79_015458	G3HN19	G3HWU5	C-C motif chemokine 21a.	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.829
Ccl21	Xcr1	G3HN19	G3HWT9	C-C motif chemokine 21a.	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.705
CgPICR_003405	Ccl19	G3I640	G3HN20	C-C motif chemokine.	C-C motif chemokine.	0.571
CgPICR_003405	I79_015458	G3I640	G3HWU5	C-C motif chemokine.	C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.980
CgPICR_003405	Xcr1	G3I640	G3HWT9	C-C motif chemokine.	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.733
Ddit3	I79_012384	G3HW45	G3HNP2	DNA damage-inducible transcript 3.	Leukocyte common antigen.	0.412
Drd2	I79_004403	G3H2I9	G3H2J0	D(2) dopamine receptor.	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.926
Fkbp1a	I79_010444	G3H6Y5	G3HIH4	Peptidylprolyl isomerase.	Ryanodine receptor 3.	0.667
Fkbp1a	I79_010748	G3H6Y5	G3HJA6	Peptidylprolyl isomerase.	Ryanodine receptor 1.	0.848
Fkbp1a	I79_010749	G3H6Y5	G3HJA7	Peptidylprolyl isomerase.	Ryanodine receptor 1.	0.848
Fkbp1a	I79_012424	G3H6Y5	G3HNS9	Peptidylprolyl isomerase.	Ryanodine receptor 2.	0.785
Fkbp1a	I79_012425	G3H6Y5	G3HNT1	Peptidylprolyl isomerase.	Ryanodine receptor 2.	0.785
Fkbp1a	Ryr3	G3H6Y5	G3HIH5	Peptidylprolyl isomerase.	Ryanodine receptor 3.	0.667
Fkbp1b	I79_010444	G3GZP2	G3HIH4	Peptidylprolyl isomerase.	Ryanodine receptor 3.	0.659