STRINGSTRING
Neo1 Neo1 Lyplal1 Lyplal1 I79_000445 I79_000445 Ube2j1 Ube2j1 I79_000900 I79_000900 I79_001046 I79_001046 Oprm1 Oprm1 Nos1 Nos1 SIRT4 SIRT4 Ndufaf2 Ndufaf2 Pkdcc Pkdcc Frmd4a Frmd4a Ghrl Ghrl Rptor Rptor Jagn1 Jagn1 I79_002454 I79_002454 Snx3 Snx3 Derl2 Derl2 Nr1h3 Nr1h3 Madd Madd Ptpmt1 Ptpmt1 Fkbp1b Fkbp1b Yod1 Yod1 I79_003549 I79_003549 Chp1 Chp1 Akap1 Akap1 Rab11fip1 Rab11fip1 Psmd9 Psmd9 I79_004244 I79_004244 Erp29 Erp29 I79_004339 I79_004339 Drd2 Drd2 I79_004403 I79_004403 I79_004628 I79_004628 F2r F2r I79_005107 I79_005107 I79_005696 I79_005696 I79_005742 I79_005742 Sytl4 Sytl4 Ghsr Ghsr I79_006005 I79_006005 CgPICR_019210 CgPICR_019210 I79_006703 I79_006703 Pfkl Pfkl Sumo3 Sumo3 I79_007339 I79_007339 I79_007441 I79_007441 I79_007548 I79_007548 ENY2 ENY2 Cdk5 Cdk5 Rsad2 Rsad2 I79_008584 I79_008584 IL12B IL12B I79_008932 I79_008932 Kcnb1 Kcnb1 I79_009077 I79_009077 Midn Midn I79_009371 I79_009371 Erlec1 Erlec1 Ppm1f Ppm1f Vsnl1 Vsnl1 Ndfip2 Ndfip2 Sfrp1 Sfrp1 I79_010155 I79_010155 I79_010194 I79_010194 Pde1c Pde1c Crhr2 Crhr2 Pkig Pkig I79_011940 I79_011940 I79_012163 I79_012163 Apoe Apoe I79_012722 I79_012722 I79_013556 I79_013556 I79_013773 I79_013773 I79_013817 I79_013817 Adtrp Adtrp Inpp5k Inpp5k Rhbdf2 Rhbdf2 Chga Chga Gopc Gopc Npff Npff Bard1 Bard1 Mtnr1a Mtnr1a Os9 Os9 Rab23 Rab23 I79_015809 I79_015809 I79_015904 I79_015904 Kcnq1 Kcnq1 Derl3 Derl3 Rab11fip5 Rab11fip5 I79_016038 I79_016038 Adipoq Adipoq Ppp2ca Ppp2ca Foxo1 Foxo1 Wwp2 Wwp2 Hnf4a Hnf4a IL1B IL1B Sergef Sergef I79_017352 I79_017352 Pim3 Pim3 I79_017834 I79_017834 Drd4 Drd4 Dph3 Dph3 Fam3d Fam3d Rangap1 Rangap1 Anxa5 Anxa5 Anxa1 Anxa1 Syt4 Syt4 Adra2a Adra2a Ei24 Ei24 Snx12 Snx12 Rest Rest Ucp3 Ucp3 Rhbdf1 Rhbdf1 Gdi1 Gdi1 I79_021283 I79_021283 Bag3 Bag3 H671_3g10030 H671_3g10030 Irs1 Irs1 I79_021835 I79_021835 I79_021836 I79_021836 I79_021837 I79_021837 I79_022343 I79_022343 I79_022515 I79_022515 I79_022888 I79_022888 Idh2 Idh2 Itgb1bp1 Itgb1bp1 I79_023475 I79_023475 Csk Csk I79_023892 I79_023892 I79_025031 I79_025031 I79_025512 I79_025512 Hadh Hadh I79_026075 I79_026075
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neo1Neogenin. (1405 aa)
Lyplal1Lysophospholipase-like protein 1. (195 aa)
I79_000445Fermitin family-like 1. (641 aa)
Ube2j1Ubiquitin-conjugating enzyme E2 J1. (303 aa)
I79_000900Acyl-protein thioesterase 1. (174 aa)
I79_001046Neurofibromin. (2164 aa)
Oprm1Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (394 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (1413 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (255 aa)
Ndufaf2Mimitin, mitochondrial. (168 aa)
PkdccProtein kinase-like protein SgK493. (252 aa)
Frmd4aFERM domain-containing protein 4A. (738 aa)
GhrlAppetite-regulating hormone. (100 aa)
RptorRegulatory-associated protein of mTOR. (1331 aa)
Jagn1Protein jagunal-like 1. (183 aa)
I79_002454Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (503 aa)
Snx3Sorting nexin-3. (118 aa)
Derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (113 aa)
Nr1h3Oxysterols receptor LXR-alpha. (402 aa)
MaddMAP kinase-activating death domain protein. (1585 aa)
Ptpmt1Protein-tyrosine phosphatase mitochondrial 1. (126 aa)
Fkbp1bPeptidylprolyl isomerase. (143 aa)
Yod1Ubiquitin thioesterase OTU1. (232 aa)
I79_003549D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (421 aa)
Chp1Calcium-binding protein p22. (195 aa)
Akap1A kinase anchor protein 1, mitochondrial. (524 aa)
Rab11fip1Rab11 family-interacting protein 1. (1089 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (222 aa)
I79_004244Tyrosine-protein phosphatase non-receptor type 11. (583 aa)
Erp29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (260 aa)
I79_004339Serine/threonine-protein phosphatase. (244 aa)
Drd2D(2) dopamine receptor. (274 aa)
I79_004403D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (187 aa)
I79_004628Phosphodiesterase. (786 aa)
F2rProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (396 aa)
I79_005107Phosphodiesterase. (620 aa)
I79_005696p130Cas-associated protein. (1144 aa)
I79_005742Synaptotagmin-like protein 4. (474 aa)
Sytl4Synaptotagmin-like protein 4. (150 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
I79_006005Melatonin receptor type 1B; Belongs to the G-protein coupled receptor 1 family. (240 aa)
CgPICR_019210Melatonin receptor type 1B. (112 aa)
I79_006703Acyl-protein thioesterase 1. (140 aa)
Pfkl6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (745 aa)
Sumo3Ubiquitin-conjugating enzyme E2 G2. (220 aa)
I79_007339Protein NOV-like. (256 aa)
I79_007441Syntaxin-binding protein 5-like. (435 aa)
I79_007548Angiopoietin-1. (112 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (131 aa)
Cdk5Cell division protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
Rsad2Radical S-adenosyl methionine domain-containing protein 2. (361 aa)
I79_008584Krueppel-like factor 7. (301 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
I79_008932Alpha-L-iduronidase. (625 aa)
Kcnb1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (706 aa)
I79_009077Potassium voltage-gated channel subfamily B member 1. (188 aa)
MidnMidnolin. (317 aa)
I79_009371Calcium-binding protein p22. (182 aa)
Erlec1Endoplasmic reticulum lectin 1. (483 aa)
Ppm1fProtein phosphatase 1F. (448 aa)
Vsnl1Visinin-like protein 1. (191 aa)
Ndfip2Uncharacterized protein. (140 aa)
Sfrp1Secreted frizzled-related protein 1. (104 aa)
I79_010155Sterol regulatory element-binding protein 1. (1050 aa)
I79_010194Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (387 aa)
Pde1cPhosphodiesterase. (583 aa)
Crhr2Corticotropin-releasing factor receptor 2; Belongs to the G-protein coupled receptor 2 family. (396 aa)
PkigcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (75 aa)
I79_011940Platelet glycoprotein 4; Belongs to the CD36 family. (348 aa)
I79_012163Etoposide-induced protein 2.4-like. (140 aa)
ApoeApolipoprotein E. (313 aa)
I79_012722Major urinary protein 5; Belongs to the calycin superfamily. Lipocalin family. (153 aa)
I79_013556Fibrillin-1. (2698 aa)
I79_013773cGMP-inhibited 3',5'-cyclic phosphodiesterase B. (265 aa)
I79_013817NAD-dependent deacetylase sirtuin-6. (334 aa)
AdtrpUncharacterized protein C6orf105-like. (148 aa)
Inpp5kInositol polyphosphate 5-phosphatase K. (451 aa)
Rhbdf2Rhomboid family member 2. (238 aa)
ChgaChromogranin-A. (434 aa)
GopcGolgi-associated PDZ and coiled-coil motif-containing protein. (424 aa)
NpffFMRFamide-related peptides. (132 aa)
Bard1BRCA1-associated RING domain protein 1. (670 aa)
Mtnr1aMelatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (353 aa)
Os9Protein OS-9-like isoform 1. (669 aa)
Rab23Ras-related protein Rab-23. (236 aa)
I79_0158093-hydroxy-3-methylglutaryl-coenzyme A reductase. (931 aa)
I79_015904Potassium voltage-gated channel subfamily KQT member 1. (216 aa)
Kcnq1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (308 aa)
Derl3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (102 aa)
Rab11fip5Rab11 family-interacting protein 5. (1353 aa)
I79_016038Rab11 family-interacting protein 5. (51 aa)
AdipoqAdiponectin. (248 aa)
Ppp2caSerine/threonine-protein phosphatase. (303 aa)
Foxo1Forkhead box protein O1. (469 aa)
Wwp2E3 ubiquitin-protein ligase. (870 aa)
Hnf4aHepatocyte nuclear factor 4-alpha. (464 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
SergefSecretion-regulating guanine nucleotide exchange factor. (97 aa)
I79_017352ATP-binding cassette transporter sub-family C member 8. (2352 aa)
Pim3Serine/threonine-protein kinase Pim-3. (89 aa)
I79_017834Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial. (273 aa)
Drd4D(4) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
Dph3Putative DPH3 like protein. (82 aa)
Fam3dProtein FAM3D. (185 aa)
Rangap1Ran GTPase-activating protein 1. (586 aa)
Anxa5Annexin. (321 aa)
Anxa1Annexin. (346 aa)
Syt4Synaptotagmin-4. (243 aa)
Adra2aAlpha-2A adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (418 aa)
Ei24Etoposide-induced protein 2.4-like. (341 aa)
Snx12Sorting nexin-12. (162 aa)
RestRE1-silencing transcription factor. (1047 aa)
Ucp3Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (650 aa)
Rhbdf1Rhomboid family member 1. (856 aa)
Gdi1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (425 aa)
I79_021283Angiopoietin-1. (298 aa)
Bag3BAG family molecular chaperone regulator 3. (571 aa)
H671_3g10030Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (204 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
I79_021835Leucine-rich repeat serine/threonine-protein kinase 2. (354 aa)
I79_021836Leucine-rich repeat serine/threonine-protein kinase 2. (1184 aa)
I79_021837Leucine-rich repeat serine/threonine-protein kinase 2. (441 aa)
I79_022343UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1444 aa)
I79_022515Serine/threonine-protein phosphatase. (325 aa)
I79_022888Calcium-binding protein p22. (54 aa)
Idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
Itgb1bp1Integrin beta-1-binding protein 1. (199 aa)
I79_023475Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform. (81 aa)
CskTyrosine-protein kinase. (450 aa)
I79_023892TBC1 domain family member 1. (817 aa)
I79_025031TBC1 domain family member 1. (232 aa)
I79_025512Urotensin-2. (88 aa)
HadhHydroxyacyl-coenzyme A dehydrogenase, mitochondrial. (116 aa)
I79_026075Isocitrate dehydrogenase [NADP], mitochondrial. (123 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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