44 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I79_002099	Vascular endothelial growth factor receptor 1. (115 aa)
	Slc7a5	Large neutral amino acids transporter small subunit 1. (506 aa)
	I79_001046	Neurofibromin. (2164 aa)
	Atxn1	Ataxin-1. (790 aa)
	Pmp22	Peripheral myelin protein 22. (92 aa)
	I79_002693	Netrin-1. (252 aa)
	Hvcn1	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (511 aa)
	Cers2	LAG1 longevity assurance-like 2 protein. (380 aa)
	Igf1	Insulin-like growth factor I. (75 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	Ptn	Pleiotrophin. (168 aa)
	E2f1	Transcription factor E2F1. (367 aa)
	I79_008941	Receptor protein-tyrosine kinase. (962 aa)
	Vegfc	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (346 aa)
	Prkci	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (560 aa)
	Rnf10	RING finger protein 10. (759 aa)
	Gfap	Glial fibrillary acidic protein; Belongs to the intermediate filament family. (427 aa)
	H671_3g9857	Tumor necrosis factor receptor superfamily member 6-like protein. (170 aa)
	Fas	Tumor necrosis factor receptor superfamily member 6. (124 aa)
	Rb1	Retinoblastoma-associated protein. (302 aa)
	I79_014451	Pro-neuregulin-1, membrane-bound isoform. (639 aa)
	I79_014474	Cyclic AMP-responsive element-binding protein 1. (325 aa)
	I79_015109	Interleukin-6. (174 aa)
	I79_015503	Transcription factor HES-1. (92 aa)
	Tspo	Translocator protein. (169 aa)
	Ascl2	Achaete-scute-like 2. (193 aa)
	Prkch	Protein kinase C eta type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (635 aa)
	Dicer1	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (234 aa)
	Lta	Lymphotoxin-alpha; Belongs to the tumor necrosis factor family. (202 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
	I79_017352	ATP-binding cassette transporter sub-family C member 8. (2352 aa)
	Ski	Ski oncogene. (636 aa)
	Lyn	Tyrosine-protein kinase. (289 aa)
	I79_017561	Tyrosine-protein kinase Lyn. (101 aa)
	Sox10	Transcription factor SOX-10. (466 aa)
	Adcyap1	Pituitary adenylate cyclase-activating polypeptide-like protein. (176 aa)
	Ptk2	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1027 aa)
	Mtor	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2520 aa)
	Idh2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
	Mfn2	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	CgPICR_008504	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like protein. (326 aa)
	Myc	Myc proto-oncogene protein. (281 aa)
	I79_026075	Isocitrate dehydrogenase [NADP], mitochondrial. (123 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ascl2	I79_014474	G3HXZ6	G3HU68	Achaete-scute-like 2.	Cyclic AMP-responsive element-binding protein 1.	0.463
Ascl2	I79_015503	G3HXZ6	G3HWY8	Achaete-scute-like 2.	Transcription factor HES-1.	0.596
CgPICR_008504	Rb1	G3IJ56	G3HR86	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit-like protein.	Retinoblastoma-associated protein.	0.634
Dicer1	I79_014474	G3HZ70	G3HU68	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.	Cyclic AMP-responsive element-binding protein 1.	0.480
E2f1	Myc	G3HAM7	G3IP28	Transcription factor E2F1.	Myc proto-oncogene protein.	0.721
E2f1	Rb1	G3HAM7	G3HR86	Transcription factor E2F1.	Retinoblastoma-associated protein.	0.999
Fas	Tnf	G3HQY4	G3HZG9	Tumor necrosis factor receptor superfamily member 6.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.605
Gfap	I79_015109	G3HLL7	G3HVW6	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Interleukin-6.	0.654
Gfap	IL1B	G3HLL7	G3I1B0	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.567
Gfap	Igf1	G3HLL7	G3H672	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Insulin-like growth factor I.	0.497
Gfap	Sox10	G3HLL7	G3I510	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Transcription factor SOX-10.	0.439
Gfap	Tnf	G3HLL7	G3HZG9	Glial fibrillary acidic protein; Belongs to the intermediate filament family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.413
H671_3g9857	Tnf	G3HQY3	G3HZG9	Tumor necrosis factor receptor superfamily member 6-like protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.605
Hvcn1	Rb1	G3H298	G3HR86	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	Retinoblastoma-associated protein.	0.634
I79_001046	I79_008941	G3GTQ9	G3HEF7	Neurofibromin.	Receptor protein-tyrosine kinase.	0.436
I79_002099	I79_017561	G3GWH4	G3I2D2	Vascular endothelial growth factor receptor 1.	Tyrosine-protein kinase Lyn.	0.407
I79_002099	Lyn	G3GWH4	G3I2D1	Vascular endothelial growth factor receptor 1.	Tyrosine-protein kinase.	0.407
I79_002099	Ptk2	G3GWH4	G3I7E2	Vascular endothelial growth factor receptor 1.	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.448
I79_002099	Vegfc	G3GWH4	G3HGL6	Vascular endothelial growth factor receptor 1.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.911
I79_002693	Ptk2	G3GY38	G3I7E2	Netrin-1.	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.487