(22 nodes) Positive regulation of type I interferon-mediated signaling pathway network (Cricetulus griseus)

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Your Input:
	Wnt5a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
	Mmp12	Macrophage metalloelastase. (464 aa)
	I79_007070	Serine/threonine-protein kinase TBK1. (271 aa)
	I79_007301	Tripartite motif-containing protein 56. (1274 aa)
	Ikbke	Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (640 aa)
	I79_007841	Z-DNA-binding protein 1. (235 aa)
	I79_010477	Protein NLRC5. (1513 aa)
	I79_025191	Tripartite motif-containing protein 6. (212 aa)
	I79_023356	Ubiquitin carboxyl-terminal hydrolase 29; Belongs to the peptidase C19 family. (325 aa)
	I79_023355	Ubiquitin carboxyl-terminal hydrolase 29; Belongs to the peptidase C19 family. (535 aa)
	I79_023218	Interferon regulatory factor 3. (377 aa)
	I79_022189	Tripartite motif-containing protein 6. (488 aa)
	Ube2k	Ubiquitin-conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	I79_019922	Serine/threonine-protein kinase TBK1. (421 aa)
	H671_3g9402	Interferon regulatory factor 7. (473 aa)
	Rnf185	RING finger protein 185. (134 aa)
	I79_017064	Tripartite motif-containing protein 6. (58 aa)
	I79_015466	Ubiquitin carboxyl-terminal hydrolase 27. (176 aa)
	Sting1	Transmembrane protein 173. (315 aa)
	Fadd	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	Usp27x	Ubiquitin carboxyl-terminal hydrolase 27; Belongs to the peptidase C19 family. (438 aa)
	I79_011011	E3 ubiquitin-protein ligase TRIM 41. (258 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Fadd	I79_007070	G3HQ71	G3H9J6	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Serine/threonine-protein kinase TBK1.	0.421
Fadd	I79_007841	G3HQ71	G3HBK7	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Z-DNA-binding protein 1.	0.429
Fadd	I79_019922	G3HQ71	G3I8P6	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Serine/threonine-protein kinase TBK1.	0.421
H671_3g9402	I79_007070	G3I3F9	G3H9J6	Interferon regulatory factor 7.	Serine/threonine-protein kinase TBK1.	0.605
H671_3g9402	I79_007841	G3I3F9	G3HBK7	Interferon regulatory factor 7.	Z-DNA-binding protein 1.	0.581
H671_3g9402	I79_019922	G3I3F9	G3I8P6	Interferon regulatory factor 7.	Serine/threonine-protein kinase TBK1.	0.605
H671_3g9402	I79_023218	G3I3F9	G3IHC9	Interferon regulatory factor 7.	Interferon regulatory factor 3.	0.903
H671_3g9402	Ikbke	G3I3F9	G3HAZ5	Interferon regulatory factor 7.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	0.728
H671_3g9402	Sting1	G3I3F9	G3HVI0	Interferon regulatory factor 7.	Transmembrane protein 173.	0.528
I79_007070	Fadd	G3H9J6	G3HQ71	Serine/threonine-protein kinase TBK1.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.421
I79_007070	H671_3g9402	G3H9J6	G3I3F9	Serine/threonine-protein kinase TBK1.	Interferon regulatory factor 7.	0.605
I79_007070	I79_007841	G3H9J6	G3HBK7	Serine/threonine-protein kinase TBK1.	Z-DNA-binding protein 1.	0.605
I79_007070	I79_019922	G3H9J6	G3I8P6	Serine/threonine-protein kinase TBK1.	Serine/threonine-protein kinase TBK1.	0.899
I79_007070	I79_023218	G3H9J6	G3IHC9	Serine/threonine-protein kinase TBK1.	Interferon regulatory factor 3.	0.933
I79_007070	Ikbke	G3H9J6	G3HAZ5	Serine/threonine-protein kinase TBK1.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	0.945
I79_007070	Sting1	G3H9J6	G3HVI0	Serine/threonine-protein kinase TBK1.	Transmembrane protein 173.	0.953
I79_007301	Sting1	G3HA59	G3HVI0	Tripartite motif-containing protein 56.	Transmembrane protein 173.	0.662
I79_007841	Fadd	G3HBK7	G3HQ71	Z-DNA-binding protein 1.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.429
I79_007841	H671_3g9402	G3HBK7	G3I3F9	Z-DNA-binding protein 1.	Interferon regulatory factor 7.	0.581
I79_007841	I79_007070	G3HBK7	G3H9J6	Z-DNA-binding protein 1.	Serine/threonine-protein kinase TBK1.	0.605