STRINGSTRING
Acvr1 Acvr1 Acvr1b Acvr1b Snx25 Snx25 Mstn Mstn Bmp3 Bmp3 I79_023775 I79_023775 Grem1 Grem1 Acvrl1 Acvrl1 Tgfb1 Tgfb1 Inha Inha Gdf3 Gdf3 Csnk2b Csnk2b Twsg1 Twsg1 Acvr2a Acvr2a Inhbe Inhbe Inhbc Inhbc Lrp1 Lrp1 PPARG PPARG Inhba Inhba I79_014841 I79_014841 CgPICR_010134 CgPICR_010134 Smad4 Smad4 I79_013902 I79_013902 Gdf11 Gdf11 Smad7 Smad7 Bmp15 Bmp15 I79_012218 I79_012218 Bmp10 Bmp10 I79_010224 I79_010224 I79_009834 I79_009834 Tgfb3 Tgfb3 Hfe Hfe Bmp6 Bmp6 Sdcbp Sdcbp Bmp7 Bmp7 Pmepa1 Pmepa1 I79_007514 I79_007514 Smad6 Smad6 I79_006745 I79_006745 Dkk1 Dkk1 Tgfbr1 Tgfbr1 I79_006254 I79_006254 Nodal Nodal I79_005909 I79_005909 Rbpms Rbpms I79_005100 I79_005100 Gdf9 Gdf9 Nog Nog Bmpr2 Bmpr2 Emilin1 Emilin1 Tgfbr2 Tgfbr2 Bmp2 Bmp2 I79_000120 I79_000120 I79_000092 I79_000092
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Acvr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (373 aa)
Snx25Sorting nexin-25. (839 aa)
MstnGrowth/differentiation factor 8. (295 aa)
Bmp3Bone morphogenetic protein 3. (487 aa)
I79_023775Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (256 aa)
Grem1Gremlin-1. (117 aa)
Acvrl1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (776 aa)
Tgfb1Transforming growth factor beta-1. (237 aa)
InhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (367 aa)
Gdf3Growth/differentiation factor 3. (361 aa)
Csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
Twsg1Twisted gastrulation protein-like 1. (222 aa)
Acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
InhbeInhibin beta E chain. (350 aa)
InhbcInhibin beta C chain. (352 aa)
Lrp1Prolow-density lipoprotein receptor-related protein 1. (2217 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (402 aa)
InhbaInhibin beta A chain-like protein. (424 aa)
I79_014841Left-right determination factor. (368 aa)
CgPICR_010134Left-right determination factor. (365 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
I79_013902Uncharacterized protein C18orf1-like. (259 aa)
Gdf11Growth/differentiation factor 11. (268 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
Bmp15Bone morphogenetic protein 15. (369 aa)
I79_012218Succinyl-CoA:3-ketoacid-coenzyme A transferase 2A, mitochondrial. (445 aa)
Bmp10Bone morphogenetic protein 10. (399 aa)
I79_010224BMP-binding endothelial regulator protein. (371 aa)
I79_009834Disabled-like 2. (705 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
HfeHereditary hemochromatosis protein-like; Belongs to the MHC class I family. (306 aa)
Bmp6Bone morphogenetic protein 6. (296 aa)
SdcbpSyntenin-1. (298 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Pmepa1Transmembrane prostate androgen-induced protein. (222 aa)
I79_007514Growth/differentiation factor 5. (253 aa)
Smad6Mothers against decapentaplegic-like 6. (174 aa)
I79_006745Mothers against decapentaplegic-like 6. (71 aa)
Dkk1Dickkopf-related protein 1. (269 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
NodalNodal. (309 aa)
I79_005909Peptidyl-prolyl cis-trans isomerase. (242 aa)
RbpmsRNA-binding protein with multiple splicing. (116 aa)
I79_005100Growth/differentiation factor 15. (96 aa)
Gdf9Growth/differentiation factor 9. (258 aa)
NogNoggin. (117 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
Emilin1EMILIN-1. (1017 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
Bmp2Bone morphogenetic protein 2. (272 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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