STRINGSTRING
I79_009030 I79_009030 I79_000092 I79_000092 Prox1 Prox1 I79_000120 I79_000120 I79_000238 I79_000238 Jag1 Jag1 Tbx5 Tbx5 Tbx3 Tbx3 I79_001239 I79_001239 Wnt5a Wnt5a Tgfbr2 Tgfbr2 I79_001955 I79_001955 I79_001957 I79_001957 I79_002290 I79_002290 Bmpr2 Bmpr2 Smo Smo Msx2 Msx2 Nog Nog Isl1 Isl1 Gja5 Gja5 I79_006254 I79_006254 Tgfbr1 Tgfbr1 Vangl2 Vangl2 I79_006693 I79_006693 I79_006745 I79_006745 Smad6 Smad6 Tbx2 Tbx2 I79_007135 I79_007135 I79_007693 I79_007693 Bmp7 Bmp7 Nfatc1 Nfatc1 Nrp2 Nrp2 Tgfbr3 Tgfbr3 Fgfrl1 Fgfrl1 I79_009001 I79_009001 Robo1 Robo1 I79_010159 I79_010159 Acvr1 Acvr1 I79_010686 I79_010686 I79_010687 I79_010687 I79_010688 I79_010688 I79_010689 I79_010689 Mks1 Mks1 Nsd2 Nsd2 Fzd1 Fzd1 Fzd2 Fzd2 I79_011789 I79_011789 I79_011943 I79_011943 Sema3c Sema3c I79_012060 I79_012060 Heyl Heyl Notch2 Notch2 I79_012814 I79_012814 I79_012815 I79_012815 Chd7 Chd7 Smad7 Smad7 Aplnr Aplnr Smad4 Smad4 Wnt11 Wnt11 I79_015033 I79_015033 I79_015223 I79_015223 I79_015503 I79_015503 Npm3 Npm3 Nrp1 Nrp1 Dvl3 Dvl3 Tbx20 Tbx20 I79_019149 I79_019149 I79_019338 I79_019338 Hey2 Hey2 Rbpj Rbpj I79_021563 I79_021563 Sav1 Sav1 Pitx2 Pitx2 Fgfr2 Fgfr2 Rbm15 Rbm15 I79_024593 I79_024593 I79_024810 I79_024810 I79_025170 I79_025170
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I79_009030T-box transcription factor TBX1. (293 aa)
I79_000092Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Prox1Prospero homeobox protein 1. (738 aa)
I79_000120Bone morphogenetic protein 5. (260 aa)
I79_000238Zinc finger protein ZFPM1. (744 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1186 aa)
Tbx5T-box transcription factor TBX5. (518 aa)
Tbx3T-box transcription factor TBX3. (709 aa)
I79_001239Low-density lipoprotein receptor-related protein 2. (4664 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
I79_001955Slit-like 3 protein. (566 aa)
I79_001957Slit-like 3 protein. (751 aa)
I79_002290Egl nine-like 1. (183 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SmoSmoothened-like; Belongs to the G-protein coupled receptor Fz/Smo family. (984 aa)
Msx2Homeobox protein MSX-2. (267 aa)
NogNoggin. (117 aa)
Isl1Insulin gene enhancer protein ISL-1. (257 aa)
Gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
I79_006254Bone morphogenetic protein 4. (406 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (401 aa)
Vangl2Vang-like protein. (521 aa)
I79_006693Intraflagellar transport protein 88-like. (533 aa)
I79_006745Mothers against decapentaplegic-like 6. (71 aa)
Smad6Mothers against decapentaplegic-like 6. (174 aa)
Tbx2T-box transcription factor TBX2. (234 aa)
I79_007135Homeobox protein Nkx-2.5. (223 aa)
I79_007693Nitric oxide synthase; Produces nitric oxide (NO). (1129 aa)
Bmp7Bone morphogenetic protein 7. (430 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (203 aa)
Nrp2Neuropilin; Belongs to the neuropilin family. (909 aa)
Tgfbr3TGF-beta receptor type III. (849 aa)
Fgfrl1Fibroblast growth factor receptor-like 1. (503 aa)
I79_009001Zinc finger protein ZFPM2. (718 aa)
Robo1Roundabout-like 1. (129 aa)
I79_010159Roundabout-like 1. (1362 aa)
Acvr1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
I79_010686Dynein heavy chain 11, axonemal. (1291 aa)
I79_010687Dynein beta chain, ciliary. (610 aa)
I79_010688Dynein heavy chain 11, axonemal. (1168 aa)
I79_010689Dynein heavy chain 11, axonemal. (275 aa)
Mks1Meckel syndrome type 1 protein-like. (561 aa)
Nsd2Putative histone-lysine N-methyltransferase NSD2. (1344 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (514 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (522 aa)
I79_011789DNA-binding protein inhibitor ID-2. (185 aa)
I79_011943Semaphorin-3C. (86 aa)
Sema3cSemaphorin-3C; Belongs to the semaphorin family. (493 aa)
I79_012060Roundabout-like 2. (1397 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein. (300 aa)
Notch2Neurogenic locus notch-like protein 2. (1521 aa)
I79_012814Chromodomain-helicase-DNA-binding protein 7. (100 aa)
I79_012815Chromodomain-helicase-DNA-binding protein 7. (150 aa)
Chd7Chromodomain-helicase-DNA-binding protein 7. (615 aa)
Smad7Mothers against decapentaplegic-like 7. (256 aa)
AplnrApelin receptor; Belongs to the G-protein coupled receptor 1 family. (377 aa)
Smad4Mothers against decapentaplegic-like 4. (259 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
I79_015033Hairy/enhancer-of-split related with YRPW motif protein 1. (199 aa)
I79_015223Neurogenic locus notch-like protein 2. (248 aa)
I79_015503Transcription factor HES-1. (92 aa)
Npm3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (337 aa)
Nrp1Neuropilin; Belongs to the neuropilin family. (923 aa)
Dvl3Segment polarity protein dishevelled-like DVL-3. (503 aa)
Tbx20T-box transcription factor TBX20. (445 aa)
I79_019149Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (132 aa)
I79_019338Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (276 aa)
RbpjRecombining binding protein suppressor of hairless-like protein. (486 aa)
I79_021563Dynein heavy chain 11, axonemal. (119 aa)
Sav1Protein salvador-like 1. (210 aa)
Pitx2Homeobox protein. (322 aa)
Fgfr2Fibroblast growth factor receptor 2. (659 aa)
Rbm15Putative RNA-binding protein 15. (912 aa)
I79_024593Uncharacterized protein. (194 aa)
I79_024810Cryptic protein. (69 aa)
I79_025170Slit-like 2 protein. (345 aa)
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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