12 items (Cricetulus griseus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Map2k1	Dual specificity mitogen-activated protein kinase kinase 1. (101 aa)
	Ctnnb1	Catenin beta-1. (781 aa)
	I79_007641	Low-density lipoprotein receptor-related protein 6. (543 aa)
	Lrp6	Low-density lipoprotein receptor-related protein 6. (565 aa)
	I79_009500	Mitogen-activated protein kinase 1. (68 aa)
	Map2k2	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (380 aa)
	I79_016797	Dual specificity mitogen-activated protein kinase kinase 1. (129 aa)
	Tgfbr2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
	Mapk3	Mitogen-activated protein kinase. (408 aa)
	I79_006225	Sonic hedgehog protein. (226 aa)
	I79_006254	Bone morphogenetic protein 4. (406 aa)
	Wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ctnnb1	I79_006225	G3H996	G3H796	Catenin beta-1.	Sonic hedgehog protein.	0.553
Ctnnb1	I79_006254	G3H996	G3H7C4	Catenin beta-1.	Bone morphogenetic protein 4.	0.448
Ctnnb1	I79_007641	G3H996	G3HB26	Catenin beta-1.	Low-density lipoprotein receptor-related protein 6.	0.686
Ctnnb1	I79_009500	G3H996	G3HFY3	Catenin beta-1.	Mitogen-activated protein kinase 1.	0.529
Ctnnb1	Lrp6	G3H996	G3HB27	Catenin beta-1.	Low-density lipoprotein receptor-related protein 6.	0.686
Ctnnb1	Map2k2	G3H996	G3HSM1	Catenin beta-1.	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	0.445
Ctnnb1	Mapk3	G3H996	G3I4H1	Catenin beta-1.	Mitogen-activated protein kinase.	0.651
Ctnnb1	Tgfbr2	G3H996	G3GV87	Catenin beta-1.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.597
Ctnnb1	Wnt7b	G3H996	G3ICH8	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.520
I79_006225	Ctnnb1	G3H796	G3H996	Sonic hedgehog protein.	Catenin beta-1.	0.553
I79_006225	I79_006254	G3H796	G3H7C4	Sonic hedgehog protein.	Bone morphogenetic protein 4.	0.605
I79_006254	Ctnnb1	G3H7C4	G3H996	Bone morphogenetic protein 4.	Catenin beta-1.	0.448
I79_006254	I79_006225	G3H7C4	G3H796	Bone morphogenetic protein 4.	Sonic hedgehog protein.	0.605
I79_006254	Tgfbr2	G3H7C4	G3GV87	Bone morphogenetic protein 4.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.509
I79_007641	Ctnnb1	G3HB26	G3H996	Low-density lipoprotein receptor-related protein 6.	Catenin beta-1.	0.686
I79_007641	Wnt7b	G3HB26	G3ICH8	Low-density lipoprotein receptor-related protein 6.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.503
I79_009500	Ctnnb1	G3HFY3	G3H996	Mitogen-activated protein kinase 1.	Catenin beta-1.	0.529
I79_009500	I79_016797	G3HFY3	G3I0B8	Mitogen-activated protein kinase 1.	Dual specificity mitogen-activated protein kinase kinase 1.	0.868
I79_009500	Map2k1	G3HFY3	G3INJ6	Mitogen-activated protein kinase 1.	Dual specificity mitogen-activated protein kinase kinase 1.	0.899
I79_009500	Map2k2	G3HFY3	G3HSM1	Mitogen-activated protein kinase 1.	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	0.911