(17 nodes) Apoptotic process involved in morphogenesis network (Cricetulus griseus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	I79_007135	Homeobox protein Nkx-2.5. (223 aa)
	Bak1	Bcl-2-likeous antagonist/killer. (209 aa)
	I79_025795	Vitamin D3 receptor. (86 aa)
	Vdr	Vitamin D3 receptor. (372 aa)
	Wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	Lrp5	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1608 aa)
	Fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
	I79_017833	Lymphoid enhancer-binding factor 1. (276 aa)
	I79_015381	Protein scribble-like. (789 aa)
	Fzd5	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (616 aa)
	I79_003468	Bcl-2-like protein 11. (141 aa)
	Ppp2r1b	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa)
	Cryab	Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
	I79_004721	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa)
	Bmp7	Bone morphogenetic protein 7. (430 aa)
	I79_010622	Leucine-rich repeat-containing protein 1. (119 aa)
	Lrrc1	Leucine-rich repeat-containing protein 1. (167 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bak1	I79_003468	A1E3K4	G3H020	Bcl-2-likeous antagonist/killer.	Bcl-2-like protein 11.	0.916
Bmp7	Fgf4	G3HBL1	G3I4D8	Bone morphogenetic protein 7.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.409
Fgf4	Bmp7	G3I4D8	G3HBL1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 7.	0.409
Fzd5	Lrp5	G3HU61	G3I5B4	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.968
Fzd5	Wnt7b	G3HU61	G3ICH8	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.847
I79_003468	Bak1	G3H020	A1E3K4	Bcl-2-like protein 11.	Bcl-2-likeous antagonist/killer.	0.916
I79_010622	I79_015381	G3HIZ0	G3HWJ7	Leucine-rich repeat-containing protein 1.	Protein scribble-like.	0.699
I79_010622	Lrrc1	G3HIZ0	G3HIZ1	Leucine-rich repeat-containing protein 1.	Leucine-rich repeat-containing protein 1.	0.899
I79_015381	I79_010622	G3HWJ7	G3HIZ0	Protein scribble-like.	Leucine-rich repeat-containing protein 1.	0.699
I79_017833	Lrp5	G3I333	G3I5B4	Lymphoid enhancer-binding factor 1.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.506
Lrp5	Fzd5	G3I5B4	G3HU61	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.968
Lrp5	I79_017833	G3I5B4	G3I333	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Lymphoid enhancer-binding factor 1.	0.506
Lrp5	Wnt7b	G3I5B4	G3ICH8	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.912
Lrrc1	I79_010622	G3HIZ1	G3HIZ0	Leucine-rich repeat-containing protein 1.	Leucine-rich repeat-containing protein 1.	0.899
Wnt7b	Fzd5	G3ICH8	G3HU61	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.847
Wnt7b	Lrp5	G3ICH8	G3I5B4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.912