(22 nodes) Intestinal epithelial cell differentiation network (Cricetulus griseus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Src	Tyrosine-protein kinase. (536 aa)
	Tyms	Thymidylate synthase-like protein. (307 aa)
	Yipf6	Protein YIPF. (235 aa)
	Sav1	Protein salvador-like 1. (210 aa)
	Dicer1	Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1907 aa)
	Hif1a	Hypoxia-inducible factor 1 alpha. (820 aa)
	Nkx3-2	Homeobox protein Nkx-3.2. (261 aa)
	Prdm1	PR domain zinc finger protein 1. (825 aa)
	I79_015041	Thymidylate synthase. (192 aa)
	Fzd5	Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (616 aa)
	Spdef	SAM pointed domain-containing Ets transcription factor. (325 aa)
	Cdh1	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (744 aa)
	C1galt1	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1. (279 aa)
	Il6st	Interleukin-6 receptor subunit beta. (914 aa)
	Ptk6	Tyrosine-protein kinase. (450 aa)
	Gata5	Transcription factor GATA-5. (406 aa)
	Cbfa2t2	Protein CBFA2T2. (574 aa)
	Klf5	Krueppel-like factor 5. (366 aa)
	Nkx3-1	Homeobox protein Nkx-3.1. (187 aa)
	I79_001484	65 kDa Yes-associated protein. (257 aa)
	Tigar	Putative fructose-2,6-bisphosphatase TIGAR. (266 aa)
	I79_000973	Transcription factor SOX-10. (360 aa)

Your Current Organism:

Cricetulus griseus

NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdh1	I79_000973	G3HKU8	G3GTI9	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Transcription factor SOX-10.	0.403
Cdh1	Src	G3HKU8	G3GXX7	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Tyrosine-protein kinase.	0.689
Gata5	I79_000973	G3HGW9	G3GTI9	Transcription factor GATA-5.	Transcription factor SOX-10.	0.605
Hif1a	Ptk6	G3HZ04	G3HGZ0	Hypoxia-inducible factor 1 alpha.	Tyrosine-protein kinase.	0.519
Hif1a	Src	G3HZ04	G3GXX7	Hypoxia-inducible factor 1 alpha.	Tyrosine-protein kinase.	0.558
I79_000973	Cdh1	G3GTI9	G3HKU8	Transcription factor SOX-10.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.403
I79_000973	Gata5	G3GTI9	G3HGW9	Transcription factor SOX-10.	Transcription factor GATA-5.	0.605
I79_001484	Sav1	G3GUW0	G3IDP2	65 kDa Yes-associated protein.	Protein salvador-like 1.	0.798
I79_001484	Src	G3GUW0	G3GXX7	65 kDa Yes-associated protein.	Tyrosine-protein kinase.	0.654
Il6st	Src	G3HHX0	G3GXX7	Interleukin-6 receptor subunit beta.	Tyrosine-protein kinase.	0.403
Ptk6	Hif1a	G3HGZ0	G3HZ04	Tyrosine-protein kinase.	Hypoxia-inducible factor 1 alpha.	0.519
Ptk6	Src	G3HGZ0	G3GXX7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.577
Sav1	I79_001484	G3IDP2	G3GUW0	Protein salvador-like 1.	65 kDa Yes-associated protein.	0.798
Src	Cdh1	G3GXX7	G3HKU8	Tyrosine-protein kinase.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.689
Src	Hif1a	G3GXX7	G3HZ04	Tyrosine-protein kinase.	Hypoxia-inducible factor 1 alpha.	0.558
Src	I79_001484	G3GXX7	G3GUW0	Tyrosine-protein kinase.	65 kDa Yes-associated protein.	0.654
Src	Il6st	G3GXX7	G3HHX0	Tyrosine-protein kinase.	Interleukin-6 receptor subunit beta.	0.403
Src	Ptk6	G3GXX7	G3HGZ0	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.577